Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Alice, Meng"'
Autor:
Alexandre Champroux, Yang Tang, David A. Dickson, Alice Meng, Anne Harrington, Lucy Liaw, Matteo Marzi, Francesco Nicassio, Thorsten M. Schlaeger, Larry A. Feig
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTThe transgenerational effects of exposing male mice to chronic social instability (CSI) stress are associated with decreased sperm levels of multiple members of the miR-34/449 family that persist after their mating through preimplantation emb
Externí odkaz:
https://doaj.org/article/cdd068c54c754aedaf907f3afdbfdc14
Autor:
Pratiti Bandopadhayay, Federica Piccioni, Ryan O’Rourke, Patricia Ho, Elizabeth M. Gonzalez, Graham Buchan, Kenin Qian, Gabrielle Gionet, Emily Girard, Margo Coxon, Matthew G. Rees, Lisa Brenan, Frank Dubois, Ofer Shapira, Noah F. Greenwald, Melanie Pages, Amanda Balboni Iniguez, Brenton R. Paolella, Alice Meng, Claire Sinai, Giovanni Roti, Neekesh V. Dharia, Amanda Creech, Benjamin Tanenbaum, Prasidda Khadka, Adam Tracy, Hong L. Tiv, Andrew L. Hong, Shannon Coy, Rumana Rashid, Jia-Ren Lin, Glenn S. Cowley, Fred C. Lam, Amy Goodale, Yenarae Lee, Kathleen Schoolcraft, Francisca Vazquez, William C. Hahn, Aviad Tsherniak, James E. Bradner, Michael B. Yaffe, Till Milde, Stefan M. Pfister, Jun Qi, Monica Schenone, Steven A. Carr, Keith L. Ligon, Mark W. Kieran, Sandro Santagata, James M. Olson, Prafulla C. Gokhale, Jacob D. Jaffe, David E. Root, Kimberly Stegmaier, Cory M. Johannessen, Rameen Beroukhim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
BET-bromodomain inhibitors could be used to treat medulloblastoma tumors with Myc amplifications. Here, the authors show that both the response and resistance to BET inhibitors in mice is mediated by bHLH/homeobox transcription factors.
Externí odkaz:
https://doaj.org/article/f1ab52ee34d04a798436204eedf97a8a
Autor:
Patricia R. Goodwin, Alice Meng, Jessie Moore, Michael Hobin, Tudor A. Fulga, David Van Vactor, Leslie C. Griffith
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3776-3786 (2018)
Summary: To discover microRNAs that regulate sleep, we performed a genetic screen using a library of miRNA sponge-expressing flies. We identified 25 miRNAs that regulate baseline sleep; 17 were sleep-promoting and 8 promoted wake. We identified one m
Externí odkaz:
https://doaj.org/article/d1eeba5feae442a084db8d9f86b34512
Autor:
Renea A. Taylor, Michael Fraser, Julie Livingstone, Shadrielle Melijah G. Espiritu, Heather Thorne, Vincent Huang, Winnie Lo, Yu-Jia Shiah, Takafumi N. Yamaguchi, Ania Sliwinski, Sheri Horsburgh, Alice Meng, Lawrence E. Heisler, Nancy Yu, Fouad Yousif, Melissa Papargiris, Mitchell G. Lawrence, Lee Timms, Declan G. Murphy, Mark Frydenberg, Julia F. Hopkins, Damien Bolton, David Clouston, John D. McPherson, Theodorus van der Kwast, Paul C. Boutros, Gail P. Risbridger, Robert G. Bristow
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Men that carrierBRCA2germline mutations are at risk of developing prostate cancer. Here, the authors analyse the genomes of prostate cancer from these individuals and demonstrate increased genomic instability in comparison to sporadic prostate cancer
Externí odkaz:
https://doaj.org/article/8d920a8293a04405b9542b7f3b199b5c
Publikováno v:
Nature Metabolism. 4:627-643
Brain-derived neurotrophic factor (BDNF) is essential for maintaining energy and glucose balance within the central nervous system. Because the study of its metabolic actions has been limited to effects in neuronal cells, its role in other cell types
Autor:
Alexandre Champroux, Tang Yang, David A. Dickson, Alice Meng, Anne Harrington, Lucy Liaw, Matteo Marzi, Francesco Nicassio, Thorsten M. Schlaeger, Larry A. Feig
Chronically stressing male mice can alter the behavior of their offspring across generations. This effect is thought to be mediated by stress-induced changes in the content of specific sperm miRNAs that modify embryo development after their delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25243c0f42e00fa64fcd074b2a847683
https://doi.org/10.1101/2023.04.21.537854
https://doi.org/10.1101/2023.04.21.537854
Autor:
Robert G. Bristow, Paul C. Boutros, Tarek A. Bismar, Wan Lam, Jeremy Squire, Colin Collins, Fred Saad, Michael Milosevic, Andrew Evans, Theodorus van der Kwast, Gyorgy Petrovics, Anthony M. Joshua, John Srigley, Chad Maloff, Alice Meng, Adrian Ishkanian, Fiona Warde, Jenna Sykes, Emilie Lalonde, Alan Dal Pra
Supplementary Figure 5 - PDF file 61K, Univariate Kaplan-Meier plots of biochemical relapse-free survival in a subgroup of patients treated without androgen deprivation therapy (ADT) in the (A) aCGH- and (B) IHC-cohorts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65bec424a3aa316fba6fc0077ada5f92
https://doi.org/10.1158/1078-0432.22452212.v1
https://doi.org/10.1158/1078-0432.22452212.v1
Autor:
Robert G. Bristow, Theo van der Kwast, Igor Jurisica, Omer Ahmed, Alice Meng, Varune Rohan Ramnarine, Jenna Sykes, Melania Pintilie, Jeremy A. Squire, Wan L. Lam, Chad A. Malloff, Cherry L. Have, John Thoms, Michael Milosevic, Adrian S. Ishkanian, Gaetano Zafarana, Jennifer A. Locke
PDF file - 41K, Percentage genome alteration (PGA) levels are displayed for patient biopsies categorized as per their NKX3.1/T-category status (a), NKX3.1/PSA status (b), NKX3.1/Gleason-score status (c), NKX3.1/c-MYC/T-category status (d) and NKX3.1/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35d84b0dd25aadc18202def37b13754
https://doi.org/10.1158/1078-0432.22447703
https://doi.org/10.1158/1078-0432.22447703
Autor:
Robert G. Bristow, Theo van der Kwast, Igor Jurisica, Omer Ahmed, Alice Meng, Varune Rohan Ramnarine, Jenna Sykes, Melania Pintilie, Jeremy A. Squire, Wan L. Lam, Chad A. Malloff, Cherry L. Have, John Thoms, Michael Milosevic, Adrian S. Ishkanian, Gaetano Zafarana, Jennifer A. Locke
Supplementary Figure Legends 1-2, Tables 1-6 from NKX3.1 Haploinsufficiency Is Prognostic for Prostate Cancer Relapse following Surgery or Image-Guided Radiotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c741d5204d4fbb34561b1cd3346642ee
https://doi.org/10.1158/1078-0432.22447700.v1
https://doi.org/10.1158/1078-0432.22447700.v1
Autor:
Robert G. Bristow, Paul C. Boutros, Tarek A. Bismar, Wan Lam, Jeremy Squire, Colin Collins, Fred Saad, Michael Milosevic, Andrew Evans, Theodorus van der Kwast, Gyorgy Petrovics, Anthony M. Joshua, John Srigley, Chad Maloff, Alice Meng, Adrian Ishkanian, Fiona Warde, Jenna Sykes, Emilie Lalonde, Alan Dal Pra
Supplementary Figure 3 - PDF file 164K, A) Univariate Kaplan-Meier plots of biochemical relapse-free rates (bRFR) according to PSA levels in the aCGH-cohort. B) Univariate Kaplan-Meier plots of biochemical relapse-free rates (bRFR) according to T-cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0927af170a3cdf061889c94f57a444
https://doi.org/10.1158/1078-0432.22452218.v1
https://doi.org/10.1158/1078-0432.22452218.v1