Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ali Shahsafaei"'
Publikováno v:
Modern Pathology. 29:1050-1057
EZH2, a member of the polycomb protein group, is an important methyltransferase that is overexpressed in various neoplasms. We found that in small cell B-cell lymphomas, EZH2 is expressed in
Publikováno v:
Leukemia & Lymphoma. 53:1905-1910
Plasma cell neoplasms are common hematopoietic malignancies that recently have been shown to be driven by specific genetic events. In the past decade, immunophenotyping by flow cytometry has become an important tool in the characterization of plasma
Publikováno v:
Leukemialymphoma. 56(7)
Enhancer of zeste homolog 2 (EZH2), an epigenetic regulator and H3k27-specific histone methyltransferase, is important for transcriptional regulation. EZH2 has been found to be overexpressed in B-cell lymphomas, as well as some T-cell lymphomas. Here
Autor:
Gregory M. Cote, Robert A. Redd, Ann S. LaCasce, Donna Neuberg, Olga Pozdnyakova, Ephraim P. Hochberg, Arnold S. Freedman, David M. Dorfman, David C. Fisher, Paola Dal Cin, Eric D. Jacobsen, Ali Shahsafaei, Philippe Armand, Jennifer R. Brown
Publikováno v:
Leukemialymphoma. 56(4)
Platelet derived growth factor-α (PDGFR-α) is expressed in peripheral T cell lymphoma, not otherwise specified (PTCL, NOS). Imatinib mesylate demonstrated in vitro cytotoxicity against primary PTCL, NOS cells. We initiated a trial of imatinib in 12
Autor:
Robert D. Odze, Donald A. Antonioli, Raj K. Goyal, Ali Shahsafaei, Stuart J. Spechler, Helen H. Wang, John M. Zeroogian, Yunn Yi Chen
Publikováno v:
Human Pathology. 30:1488-1495
Acidic mucin-positive nongoblet columnar cells (NGCC) have recently been observed in the surface epithelium of the gastroesophageal junction (GEJ) and distal esophagus in resections from patients with traditional long segment (>3 cm) Barrett's esopha
Autor:
Donald A. Antonioli, Robert D. Odze, Yen Yi Chen, Helen H. Wang, Stuart J. Spechler, Raj K. Goyal, Ali Shahsafaei, John M. Zeroogian, James M Gulizia
Publikováno v:
Human Pathology. 30:412-418
Intestinalized epithelium in traditional long-segment Barrett's esophagus (BE) shows increased proliferative activity, which is postulated to be an early step in the metaplasia-dysplasia-carcinoma sequence. The aim of this study was to evaluate the p
Autor:
Robert D. Odze, Helen H. Wang, William G. Richards, X X Ali Shahsafaei, Jerrold R. Turner, Carlos Torres, David Sugarbaker
Publikováno v:
Cancer. 85:520-528
BACKGROUND The objective of this study was to evaluate a variety of histologic features, some of which to our knowledge have never been evaluated in Barrett's-associated adenocarcinoma (BAd) (such as Crohn's-like lymphoid reaction and peritumoral lym
Publikováno v:
The American journal of surgical pathology. 35(5)
Previous studies have shown that hyperplastic and serrated polyps of the colon show variable degrees of gastric and intestinal differentiation. MUCs are a class of approximately 20 genes that encode high-molecular-weight glycoproteins, or mucopolysac
Publikováno v:
Blood. 126:2660-2660
Background: EZH2, amember of the polycomb protein group, is an important methyltransferase that is over-expressed in various carcinomas, some B and T cell lymphomas, as well as myeloid disorders. We investigated EZH2 expression in the range of low an
Publikováno v:
Human pathology. 36(10)
Summary B cell–activating factor receptor (BAFF-R) is one of three known receptors for BAFF, a critical regulator of B- and T-cell function. In mice, BAFF-R is required for B-cell maturation and survival, and in mice and humans, the overproduction