Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ali Sarkeshik"'
Autor:
Judith Zich, Karen May, Konstantinos Paraskevopoulos, Onur Sen, Heather M Syred, Sjaak van der Sar, Hitesh Patel, James J Moresco, Ali Sarkeshik, John R Yates, Juri Rappsilber, Kevin G Hardwick
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1006009 (2016)
Externí odkaz:
https://doaj.org/article/e09d946afa2c43359a9576b99b1746b3
Autor:
Judith Zich, Karen May, Konstantinos Paraskevopoulos, Onur Sen, Heather M Syred, Sjaak van der Sar, Hitesh Patel, James J Moresco, Ali Sarkeshik, John R Yates, Juri Rappsilber, Kevin G Hardwick
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005834 (2016)
The spindle checkpoint is a mitotic surveillance system which ensures equal segregation of sister chromatids. It delays anaphase onset by inhibiting the action of the E3 ubiquitin ligase known as the anaphase promoting complex or cyclosome (APC/C). M
Externí odkaz:
https://doaj.org/article/d8fbeccbac424c65aaf49c96458f0809
Publikováno v:
eLife, Vol 1 (2012)
Chromatin boundaries subdivide eukaryotic chromosomes into functionally autonomous domains of genetic activity. This subdivision insulates genes and/or regulatory elements within a domain from promiscuous interactions with nearby domains. While it wa
Externí odkaz:
https://doaj.org/article/ac4ee55961644bb487ebd502bcd03293
Autor:
Rhishikesh Bargaje, Shivani Gupta, Ali Sarkeshik, Robin Park, Tao Xu, Maharnob Sarkar, Mahantappa Halimani, Soumya Sinha Roy, John Yates, Beena Pillai
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43243 (2012)
MicroRNAs (miRNAs) are short regulatory RNA molecules that interfere with the expression of target mRNA by binding to complementary sequences. Currently, the most common method for identification of targets of miRNAs is computational prediction based
Externí odkaz:
https://doaj.org/article/3f841ddd9c3c47e6b5ecc7a197512fdb
Autor:
Li Chin Wong, Alexandre Costa, Ian McLeod, Ali Sarkeshik, John Yates, Saw Kyin, David Perlman, Paul Schedl
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24355 (2011)
The Orb CPEB protein regulates translation of localized mRNAs in Drosophila ovaries. While there are multiple hypo- and hyperphosphorylated Orb isoforms in wild type ovaries, most are missing in orb(F303), which has an amino acid substitution in a bu
Externí odkaz:
https://doaj.org/article/c8abd26a2aad41bba722dd926f5cad68
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20489 (2011)
Mitosis is a fundamental process in the development of all organisms. The mitotic spindle guides the cell through mitosis as it mediates the segregation of chromosomes, the orientation of the cleavage furrow, and the progression of cell division. Bir
Externí odkaz:
https://doaj.org/article/137a0ab58ff14ce9b83a9f7d5f0cc1df
Autor:
Samuel L Hutson, Ernest Mui, Karen Kinsley, William H Witola, Michael S Behnke, Kamal El Bissati, Stephen P Muench, Brittany Rohrman, Susan R Liu, Robert Wollmann, Yuko Ogata, Ali Sarkeshik, John R Yates, Rima McLeod
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e14057 (2010)
Molecular pathways regulating rapid proliferation and persistence are fundamental for pathogens but are not elucidated fully in Toxoplasma gondii. Promoters of T. gondii ribosomal proteins (RPs) were analyzed by EMSAs and ChIP. One RP promoter domain
Externí odkaz:
https://doaj.org/article/974f68e15d6742f48d83dac39db9960b
Autor:
P. Todd Stukenberg, Daniel R. Foltz, John R. Yates, Ewelina Zasadzińska, Courtney A. Kestner, Erin C. Moran, Henry DeHoyos, Limin Liu, Ali Sarkeshik
Recent work has shown that R-loops exist at mitotic centromeres, but the function of these R-loops is not well understood. Here, we report that mitotic R-loops arise in distinct locations from those formed during interphase. They accumulate on chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be42a496b3a51e5414286fd467fa475b
https://doi.org/10.1101/2021.01.14.426738
https://doi.org/10.1101/2021.01.14.426738
Autor:
Lei Wang, Anjon Audhya, Amber L. Schuh, John R. Yates, Kyle Quinney, Ali Sarkeshik, Michael G. Hanna
Publikováno v:
Biochemical Journal. 466:625-637
Members of the endosomal sorting complex required for transport (ESCRT) machinery function in membrane remodelling processes during multivesicular endosome (MVE) biogenesis, cytokinesis, retroviral budding and plasma membrane repair. During luminal v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52da6a7ab824e9611151b3e89d659a42
https://doi.org/10.1042/bj20141202
https://doi.org/10.1042/bj20141202
Autor:
Ali Sarkeshik, Godfried W. van der Heijden, Julio Castañeda, Pavol Genzor, John R. Yates, Nicholas T. Ingolia, Alex Bortvin
Publikováno v:
The EMBO Journal. 33:1999-2019
Pachytene piRNAs are a class of Piwi-interacting small RNAs abundant in spermatids of the adult mouse testis. They are processed from piRNA primary transcripts by a poorly understood mechanism and, unlike fetal transposon-derived piRNAs, lack complem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fa7649508273c2d9c4b7f91dff5f7e8
https://doi.org/10.15252/embj.201386855
https://doi.org/10.15252/embj.201386855