Systemic bis-phosphinic acid derivative restores chloride transport in Cystic Fibrosis mice

Autor: Mélanie Faria da Cunha, Iwona Pranke, Ali Sassi, Christiane Schreiweis, Stéphanie Moriceau, Dragana Vidovic, Aurélie Hatton, Mariane Sylvia Carlon, Geordie Creste, Farouk Berhal, Guillaume Prestat, Romain Freund, Norbert Odolczyk, Jean Philippe Jais, Christine Gravier-Pelletier, Piotr Zielenkiewicz, Vincent Jullien, Alexandre Hinzpeter, Franck Oury, Aleksander Edelman, Isabelle Sermet-Gaudelus

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)

Abstract Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator gene (CFTR) are responsible for Cystic Fibrosis (CF). The most common CF-causing mutation is the deletion of the 508th amino-acid of CFTR (F508del), leading to dysregulatio

Externí odkaz: https://doaj.org/article/b8ed4d53b6aa41a99e5f64c0f4e97140

Knock Out of CGN and CGNL1 in MDCK Cells Affects Claudin-2 but Has a Minor Impact on Tight Junction Barrier Function

Autor: Marine Maupérin, Ali Sassi, Isabelle Méan, Eric Feraille, Sandra Citi

Publikováno v: Cells, Vol 12, Iss 15, p 2004 (2023)

Cingulin (CGN) and paracingulin (CGNL1) are cytoplasmic proteins of tight junctions (TJs), where they play a role in tethering ZO-1 to the actomyosin and microtubule cytoskeletons. The role of CGN and CGNL1 in the barrier function of epithelia is not

Externí odkaz: https://doaj.org/article/83ba493373054e84aec8d6b4ed257a67

Multiple renal capillary hemangiomas in a patient with end-stage renal disease

Autor: Thanh-Lan Bui, MA, Justin Glavis-Bloom, MD, Hanna K. Liu, MD, Alexander Ushinsky, MD, Sami Souccar, MD, Ifegwu O. Ibe, MD, Ali Sasani, BS, Roozbeh Houshyar, MD

Publikováno v: Radiology Case Reports, Vol 14, Iss 6, Pp 750-754 (2019)

Renal capillary hemangiomas are rare and benign vascular tumors which are typically incidentally discovered on imaging. Surgical excision is often performed, as imaging appearance is similar to malignant lesions. Renal hemangiomas are typically solit

Externí odkaz: https://doaj.org/article/23b88599be7c4a919020b3678042d189

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Factors associated with completeness in documentation of diagnostic work-up and treatment in patients with breast cancer in Sudan.

Autor: Eltoum NI; Faculty of Medicine, University of Medical Sciences and Technology, PO Box 12810, Khartoum, Sudan.; Department of Hematology and Oncology, University of Alabama at Birmingham, 1808 7th Avenue South, Birmingham, AL 35233, USA.; https://orcid.org/0000-0003-4210-8012., Caston NE; Department of Hematology and Oncology, University of Alabama at Birmingham, 1808 7th Avenue South, Birmingham, AL 35233, USA., Gutnik L; Department of Hematology and Oncology, University of Alabama at Birmingham, 1808 7th Avenue South, Birmingham, AL 35233, USA., Alazm MAA; Faculty of Medicine, University of Medical Sciences and Technology, PO Box 12810, Khartoum, Sudan., Mohamed FO; Faculty of Medicine, University of Medical Sciences and Technology, PO Box 12810, Khartoum, Sudan., Abdalkarem LM; Faculty of Medicine, University of Medical Sciences and Technology, PO Box 12810, Khartoum, Sudan., Ali SAS; Faculty of Medicine, University of Medical Sciences and Technology, PO Box 12810, Khartoum, Sudan., Badawi AZ; Faculty of Medicine, University of Medical Sciences and Technology, PO Box 12810, Khartoum, Sudan., Henderson NL; Department of Hematology and Oncology, University of Alabama at Birmingham, 1808 7th Avenue South, Birmingham, AL 35233, USA., Azuero A; Department of Hematology and Oncology, University of Alabama at Birmingham, 1808 7th Avenue South, Birmingham, AL 35233, USA., Rocque G; Department of Hematology and Oncology, University of Alabama at Birmingham, 1808 7th Avenue South, Birmingham, AL 35233, USA.

Publikováno v: Ecancermedicalscience [Ecancermedicalscience] 2023 Nov 17; Vol. 17, pp. 1632. Date of Electronic Publication: 2023 Nov 17 (Print Publication: 2023).