Zobrazeno 1 - 10
of 397
pro vyhledávání: '"Ali S Arbab"'
Publikováno v:
Micro and Nano Systems Letters, Vol 12, Iss 1, Pp 1-9 (2024)
Abstract Two types of cells targeting Peptides, TAMS-1 (CSPGAKVRCY {Lys (Biotin)}) and MDSC-peptide (Biotin {PEG4}-MEWSLEKGYTIK), were synthesized for targeting CD206 M2 macrophage and myeloid-derived suppressor cells (MDSC), respectively. Each pepti
Externí odkaz:
https://doaj.org/article/efd45467a1e14639b5997dbf73c9575d
Autor:
Miao Yu, Gang Guo, Lei Huang, Libin Deng, Chang-Sheng Chang, Bhagelu R. Achyut, Madison Canning, Ningchun Xu, Ali S. Arbab, Roni J. Bollag, Paulo C. Rodriguez, Andrew L. Mellor, Huidong Shi, David H. Munn, Yan Cui
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Our understanding on how CAFs can be activated to support tumour progression is still limited. Here, the authors demonstrate that adenosine produced in the tumour microenvironment can enhance the expression of CD73 in CAFs ultimately driving CD8 T-Ce
Externí odkaz:
https://doaj.org/article/3a939ed9e1ba46adb3d1e889423e5b4d
Autor:
Raziye Piranlioglu, EunMi Lee, Maria Ouzounova, Roni J. Bollag, Alicia H. Vinyard, Ali S. Arbab, Daniela Marasco, Mustafa Guzel, John K. Cowell, Muthushamy Thangaraju, Ahmed Chadli, Khaled A. Hassan, Max S. Wicha, Esteban Celis, Hasan Korkaya
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Dissemination of tumor cells from the primary site is an early event. Here, the authors show that the early disseminated tumor cells are actively cleared by the host cytotoxic T lymphocytes induced by the primary tumor and that infiltration of granul
Externí odkaz:
https://doaj.org/article/ab8309125be1466c9f20adaacc94d582
Autor:
Mahmoud Elashiry, Ranya Elsayed, Mohamed M. Elashiry, Mohammad H. Rashid, Roxan Ara, Ali S. Arbab, Ahmed R. Elawady, Mark Hamrick, Yutao Liu, Wenbo Zhi, Rudolf Lucas, Jose Vazquez, Christopher W. Cutler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Dendritic cell (DC)-derived exosomes (DC EXO), natural nanoparticles of endosomal origin, are under intense scrutiny in clinical trials for various inflammatory diseases. DC EXO are eobiotic, meaning they are well-tolerated by the host; moreover, the
Externí odkaz:
https://doaj.org/article/588c763cc47243608e927a4739406756
Autor:
Mahmoud Elashiry, Mohamed M. Elashiry, Ranya Elsayed, Mythily Rajendran, Carol Auersvald, Rana Zeitoun, Mohammad H. Rashid, Roxan Ara, Mohamed M. Meghil, Yutao Liu, Ali S. Arbab, Roger M. Arce, Mark Hamrick, Mohammed Elsalanty, Marshall Brendan, Rafal Pacholczyk, Christopher W. Cutler
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Chronic bone degenerative diseases represent a major threat to the health and well-being of the population, particularly those with advanced age. This study isolated exosomes (EXO), natural nano-particles, from dendritic cells, the “directors” of
Externí odkaz:
https://doaj.org/article/264daa790bda47be9967099735a239ce
CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma
Autor:
Kartik Angara, Thaiz F. Borin, Mohammad H. Rashid, Iryna Lebedyeva, Roxan Ara, Ping-Chang Lin, ASM Iskander, Roni J. Bollag, Bhagelu R. Achyut, Ali S. Arbab
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 10, Pp 1070-1082 (2018)
BACKGROUND: Glioblastoma (GBM) was shown to relapse faster and displayed therapeutic resistance to antiangiogenic therapies (AATs) through an alternative tumor cell-driven mechanism of neovascularization called vascular mimicry (VM). We identified hi
Externí odkaz:
https://doaj.org/article/41d3f116adab4179ab365cd6ef978c71
Publikováno v:
Translational Oncology, Vol 10, Iss 4, Pp 650-660 (2017)
Glioblastoma (GBM) is a hypervascular neoplasia of the central nervous system with an extremely high rate of mortality. Owing to its hypervascularity, anti-angiogenic therapies (AAT) have been used as an adjuvant to the traditional surgical resection
Externí odkaz:
https://doaj.org/article/3c8b1c9d865744d393e1a46902fc4d15
Autor:
Maria Ouzounova, Eunmi Lee, Raziye Piranlioglu, Abdeljabar El Andaloussi, Ravindra Kolhe, Mehmet F. Demirci, Daniela Marasco, Iskander Asm, Ahmed Chadli, Khaled A. Hassan, Muthusamy Thangaraju, Gang Zhou, Ali S. Arbab, John K. Cowell, Hasan Korkaya
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Myeloid-derived suppressive cells (MDSCs) promote metastasis. Here, the authors show that the monocytic MDSCs subset promotes epithelial to mesenchymal transition at the primary site while the granulocytic subset promotes the reverse transition at th
Externí odkaz:
https://doaj.org/article/fd3befe0433a4fdaa9773cbb10f54358
Autor:
Lun Cai, Ali S. Arbab, Tae Jin Lee, Ashok Sharma, Bobby Thomas, Kazuhiko Igarashi, Raghavan Pillai Raju
Publikováno v:
Free Radical Biology and Medicine. 188:134-145
Sepsis is a complex disease due to dysregulated host response to infection. Oxidative stress and mitochondrial dysfunction leading to metabolic dysregulation are among the hallmarks of sepsis. The transcription factor NRF2 (Nuclear Factor E2-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb7a42180e0d3dec38c0829a0690a9e
https://doi.org/10.1016/j.freeradbiomed.2022.06.005
https://doi.org/10.1016/j.freeradbiomed.2022.06.005
Autor:
Deanna Doughty, Surendra K Rajpurohit, Amy Trang, Ahmet Alptekin, Ahmet K Korkaya, Bhagelu R Achyut, Ali S Arbab, Jennifer W Bradford
Publikováno v:
Exp Biol Med (Maywood)
Microglia, the tissue-resident macrophage of the central nervous system (CNS), play a paramount role in brain health and disease status. Here, we describe a novel method for enriching and isolating primary microglia from mouse brain tissue. This isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3162f53d16466ff43b425ebf09768c
https://doi.org/10.1177/15353702221096060
https://doi.org/10.1177/15353702221096060