Bortezomib‐based therapy is effective and well tolerated in frontline and multiply pre‐treated Waldenström macroglobulinaemia including BTKi failures: A real‐world analysis

Autor: Jahanzaib Khwaja, Encarl Uppal, Robert Baker, Kajal Trivedi, Ali Rismani, Rajeev Gupta, Ian Proctor, Charalampia Kyriakou, Shirley D'Sa

Publikováno v: eJHaem, Vol 3, Iss 4, Pp 1330-1334 (2022)

Abstract Waldenström macroglobulinemia (WM) is a rare, incurable low grade lymphoma following a relapsing trajectory. Management strategies have evolved with the introduction of targeted therapy including new classes of Bruton tyrosine kinase inhibi

Externí odkaz: https://doaj.org/article/1a786cdbf69941af8ac5ed3f280c90b4

Patient reported outcome measures in Waldenström macroglobulinaemia: A real‐world data analysis from the WMUK Rory Morrison Registry

Autor: Jahanzaib Khwaja, Encarl Uppal, Sotirios Bristogiannis, Helen McCarthy, Jaimal Kothari, Ali Rismani, Harriet Scorer, Jane Nicholson, Dima El‐Sharkawi, Shirley D'Sa, Charalampia Kyriakou

Publikováno v: eJHaem. 4:221-225

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5e8607c42035388628f958b2cf5e48a
https://doi.org/10.1002/jha2.640

Type 1 Cryoglobulinaemia Associated with Waldenström Macroglobulinemia, IgM MGUS or Non-Hodgkin Lymphoma

Autor: Jahanzaib Khwaja, Simon Salter, Aisha S Patel, Robert Baker, Rajeev Gupta, Ali Rismani, Charalampia Kyriakou, Ashutosh D. Wechalekar, Josephine M.I. Vos, Shirley D'Sa

Publikováno v: Blood. 140:3653-3654

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14cc4a73773d45366e407e698e6bbaf4
https://doi.org/10.1182/blood-2022-160438

Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia

Autor: Philip George, Yvette Hoade, Sahra Ali, Simon Watt, Varun Mehra, Catherine Cargo, Fergus Jack, Paul Evans, Tiziana Fanelli, William J. Tapper, Alastair Whiteway, Gabriela Sciuccati, Iwo Pieniak, Jamie Cavenagh, Emma Das-Gupta, Andres Virchis, Nicole Naumann, Kavita Patel, Rowena Thomas-Dewing, Patrick Thornton, Kris Zegocki, Louise Wallis, Charlotte Grimley, Gonzalo Carreño-Tarragona, Peter Forsyth, Andreas Reiter, Nicholas C.P. Cross, Laura Munro, Kaljit Bhuller, Andrew S Duncombe, Andrew Chase, Barbara J. Bain, Mohamad Jawhar, Johannes Lübke, Ali Rismani, Sonja Burgstaller

Publikováno v: Leukemia
Cross, N C P, Hoade, Y, Tapper, W J, Carreno-tarragona, G, Fanelli, T, Jawhar, M, Naumann, N, Pieniak, I, Lübke, J, Ali, S, Bhuller, K, Burgstaller, S, Cargo, C, Cavenagh, J, Duncombe, A S, Das-gupta, E, Evans, P, Forsyth, P, George, P, Grimley, C, Jack, F, Munro, L, Mehra, V, Patel, K, Rismani, A, Sciuccati, G, Thomas-dewing, R, Thornton, P, Virchis, A, Watt, S, Wallis, L, Whiteway, A, Zegocki, K, Bain, B J, Reiter, A & Chase, A 2018, ' Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia ', Leukemia . https://doi.org/10.1038/s41375-018-0342-3

Determining the underlying cause of persistent eosinophilia is important for effective clinical management but remains a diagnostic challenge in many cases. We identified STAT5B N642H, an established oncogenic mutation, in 27/1715 (1.6%) cases referr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e63fd9c1c690dc714a581a1415b18c
http://europepmc.org/articles/PMC6365490

IgM Paraprotein-Associated Type 1 Cryoglobulinaemia: Clinical Characteristics and Outcomes

Autor: Ali Rismani, Simon Salter, Charalampia Kyriakou, Suzanne O Arulogun, Josephine M.I. Vos, Shirley D'Sa, Aisha S Patel, Jahanzaib Khwaja

Publikováno v: Blood. 138:4503-4503

Introduction Type 1 cryoglobulinaemia (CG) is characterised by monoclonal immunoglobulins which precipitate at temperatures below 37°C and redissolve on warming. They may be associated with lymphoproliferative disorders including Waldenström's macr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b3e96fe859c5972cac636be485326cea
https://doi.org/10.1182/blood-2021-151662