Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ali R. Zomorrodi"'
Autor:
Ali R. Zomorrodi, Colin Hemez, Pol Arranz-Gibert, Terrence Wu, Farren J. Isaacs, Daniel Segrè
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104562- (2022)
Summary: Introducing heterologous pathways into host cells constitutes a promising strategy for synthesizing nonstandard amino acids (nsAAs) to enable the production of proteins with expanded chemistries. However, this strategy has proven challenging
Externí odkaz:
https://doaj.org/article/3dacac0bdcd745f69c3189ebbd410910
Autor:
Maureen M. Leonard, Hiren Karathia, Meritxell Pujolassos, Jacopo Troisi, Francesco Valitutti, Poorani Subramanian, Stephanie Camhi, Victoria Kenyon, Angelo Colucci, Gloria Serena, Salvatore Cucchiara, Monica Montuori, Basilio Malamisura, Ruggiero Francavilla, Luca Elli, Brian Fanelli, Rita Colwell, Nur Hasan, Ali R. Zomorrodi, Alessio Fasano, the CD-GEMM Team
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Background Celiac disease (CD) is an autoimmune digestive disorder that occurs in genetically susceptible individuals in response to ingesting gluten, a protein found in wheat, rye, and barley. Research shows that genetic predisposition and
Externí odkaz:
https://doaj.org/article/ce798c17b1504d999ed1882d345fbda6
Autor:
Isha Mehrotra, Gloria Serena, Murat Cetinbas, Victoria Kenyon, Victoria M. Martin, Stephanie G. Harshman, Ali R. Zomorrodi, Ruslan I. Sadreyev, Alessio Fasano, Maureen M. Leonard
Publikováno v:
Current Research in Microbial Sciences, Vol 2, Iss , Pp 100069- (2021)
Celiac Disease (CD) is an autoimmune disorder triggered by gluten ingestion that can develop in genetically predisposed individuals. Alterations in the gut microbiota have been suggested to contribute to development of autoimmune conditions including
Externí odkaz:
https://doaj.org/article/eb68a135fd1d4b1499efd1df8883e11b
Autor:
Ali R. Zomorrodi, Daniel Segrè
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The rise of metabolic interdependencies among microbes is still poorly understood. Here, taking the underlying biochemical networks into consideration, Zomorrodi and Segrè integrate genome-scale metabolic models with evolutionary game theory to stud
Externí odkaz:
https://doaj.org/article/1159c42bdb6d4755a2bef7c89b9d8d66
Autor:
Katherine L. Olshan, Ali R. Zomorrodi, Meritxell Pujolassos, Jacopo Troisi, Nayeim Khan, Brian Fanelli, Victoria Kenyon, Alessio Fasano, Maureen M. Leonard
Publikováno v:
Nutrients, Vol 13, Iss 7, p 2243 (2021)
The intestinal microbiome may trigger celiac disease (CD) in individuals with a genetic disposition when exposed to dietary gluten. Research demonstrates that nutrition during infancy is crucial to the intestinal microbiome engraftment. Very few stud
Externí odkaz:
https://doaj.org/article/404e488dde8f41ee8ca5dfcc9c586b76
Publikováno v:
Current Opinion in Systems Biology. 26:46-57
Computational modeling of microbial communities using GEnome-scale Models (GEMs) of metabolism is a new frontier in systems biology. Here, we discuss recent developments in this area ranging from high-throughput GEMs reconstruction pipelines to appro
Publikováno v:
Expert Rev Clin Immunol
INTRODUCTION: Current evidence supports a vital role of the microbiota on human health outcomes, with alterations in an otherwise healthy balance linked to chronic medical conditions such as celiac disease (CD). Recent advances in microbiome analysis
Autor:
Ali R. Zomorrodi, Colin Hemez, Pol Arranz-Gibert, Terrence Wu, Farren J. Isaacs, Daniel Segrè
SummaryIntroducing heterologous pathways into host cells constitutes a promising strategy for synthesizing nonstandard amino acids (nsAAs) to enable the production of proteins with expanded chemistries. However, this strategy has proven challenging a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f94683ce9f5ef245d37c5fe6b610c1e5
https://doi.org/10.1101/2022.04.02.486821
https://doi.org/10.1101/2022.04.02.486821
Autor:
Ali R. Zomorrodi, Ruslan I. Sadreyev, Stephanie G. Harshman, Murat Cetinbas, Victoria M. Martin, Isha Mehrotra, Gloria Serena, Alessio Fasano, Victoria Kenyon, Maureen M. Leonard
Publikováno v:
Current Research in Microbial Sciences, Vol 2, Iss, Pp 100069-(2021)
Current Research in Microbial Sciences
Current Research in Microbial Sciences
Highlights • Bacteroidetes is most abundant phylum in pediatric blood. • Beta diversity is increased in blood of children with active Celiac. • Abundance of taxa are altered in blood of children with active Celiac.
Celiac Disease (CD) is a
Celiac Disease (CD) is a
Autor:
Hiren Karathia, Brian Fanelli, Nur A. Hasan, Basilio Malamisura, Rita R. Colwell, Meritxell Pujolassos, Angelo Colucci, Luca Elli, Ruggiero Francavilla, Jacopo Troisi, Gloria Serena, Salvatore Cucchiara, Maureen M. Leonard, Chiara Maria Trovato, Stephanie Camhi, Victoria Kenyon, Francesco Valitutti, Poorani Subramanian, Alessio Fasano, Ali R. Zomorrodi
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The incidence of chronic inflammatory autoimmune conditions, such as celiac disease (CD), is increasing at an alarming rate. CD is the only autoimmune condition for which the trigger, gluten, is known. However, its etiology and pathogene