Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ali R. Alhoshani"'
Autor:
Abrar Softah, Moureq R. Alotaibi, Ali R. Alhoshani, Tareq Saleh, Khalid Alhazzani, Mashal M. Almutairi, Raed AlRowis, Samiyah Alshehri, Norah A. Albekairy, Hisashi Harada, Rowan Boyd, Eesha Chakraborty, David A. Gewirtz, Homood M. As Sobeai
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 3066 (2023)
Despite significant advances in the treatment of triple-negative breast cancer, this disease continues to pose a clinical challenge, with many patients ultimately suffering from relapse. Tumor cells that recover after entering into a state of senesce
Externí odkaz:
https://doaj.org/article/96173029af474f86b34f9dc7633ce8a7
Autor:
Homood M. As Sobeai, Munirah Alohaydib, Ali R. Alhoshani, Khalid Alhazzani, Mashal M. Almutairi, Tareq Saleh, David A. Gewirtz, Moureq R. Alotiabi
Publikováno v:
Saudi Pharmaceutical Journal, Vol 30, Iss 1, Pp 91-101 (2022)
Emerging evidence has shown that the therapy-induced senescent growth arrest in cancer cells is of durable nature whereby a subset of cells can reinstate proliferative capacity. Promising new drugs named senolytics selectively target senescent cells
Externí odkaz:
https://doaj.org/article/ebab4e61a4944dfeacbc30f621fe8003
Autor:
Homood M. As Sobeai, Adam A.A. Sulaiman, Saeed Ahmad, Abdul Rajjak Shaikh, Ridwan Sulaimon, Moureq R. Alotiabi, Fahad AlZoghaibi, Ali Osman Altoum, Anvarhusein A. Isab, Ali R. Alhoshani
Publikováno v:
Arabian Journal of Chemistry, Vol 14, Iss 7, Pp 103245- (2021)
New therapeutic options are crucially for most cancers, particularly those with poor clinical outcomes. Five new derivatives of cisplatin-containing selenone ligands with the general formula, cis-[Pt(NH3)2(Selenone)2](NO3)2 (1–5) were synthesized a
Externí odkaz:
https://doaj.org/article/602b29c31e1e45f8956a5e97627e4b3e
Autor:
Mashal M. Almutairi, Wael A. Alanazi, Musaad A. Alshammari, Moureq Rashed Alotaibi, Ali R. Alhoshani, Salim Salah Al-Rejaie, Mohamed M. Hafez, Othman A. Al-Shabanah
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 17, Iss 1, Pp 1-9 (2017)
Abstract Background Cisplatin is widely used chemotherapeutic agent for cancer treatment with limited uses due to its neurotoxic side effect. The aim of this study was to determine the potential preventive effects of rutin on the brain of cisplatin-
Externí odkaz:
https://doaj.org/article/bb034df5b71a4f72b2549d8906c0ff3c
Autor:
Ali R. Alhoshani, Mohamed M. Hafez, Sufia Husain, Abdel Malek Al-sheikh, Moureq R. Alotaibi, Salim S. Al Rejaie, Musaad A. Alshammari, Mashal M. Almutairi, Othman A. Al-Shabanah
Publikováno v:
BMC Nephrology, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Cisplatin (CP) is commonly used in the treatment of different types of cancer but nephrotoxicity has been a major limiting factor. Therefore, the present study aimed to study the possible protective effect of rutin against nephrot
Externí odkaz:
https://doaj.org/article/c92d3a4cb2634616989936dda6a15256
Autor:
Sheikh F, Ahmad, Mushtaq A, Ansari, Ahmed, Nadeem, Saleh A, Bakheet, Faleh, Alqahtani, Ali R, Alhoshani, Fawaz, Alasmari, Nasser B, Alsaleh, Sabry M, Attia
Publikováno v:
Pharmacology, biochemistry, and behavior. 189
Autism spectrum disorder (ASD) is diagnosed by core symptoms including impaired social communication and the presence of repetitive and stereotypical behaviors. There is also evidence for immune dysfunction in individuals with ASD, but it is a diseas
Autor:
Moureq R, Alotaibi, Zeinab K, Hassan, Salim S, Al-Rejaie, Musaad A, Alshammari, Mashal M, Almutairi, Ali R, Alhoshani, Wael A, Alanazi, Mohamed M, Hafez, Othman A, Al-Shabanah
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Breast cancer is affected by the immune system in that different cytokines play roles in its initiation and progression. Interleukin-10 (IL-10), an anti-inflammatory cytokine, is an immunosuppressive factor involved in tumorigenesis. The
Autor:
Othman A, AL Shabanah, Moureq rashed, Alotaibi, Salim S, Al Rejaie, Ali R, Alhoshani, Mashal M, Almutairi, Musaad A, Alshammari, Mohamed M, Hafez
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Objective: Breast cancer is global female health problem worldwide. Most of the currently used agents for breast cancer treatment have toxic side-effects. Ginseng root, an oriental medicine, has many health benefits and may exhibit direct anti-cancer
Autor:
Mohamed M, Hafez, Sherifa S, Hamed, Manal F, El-Khadragy, Zeinab K, Hassan, Salim S, Al Rejaie, Mohamed M, Sayed-Ahmed, Naif O, Al-Harbi, Khalid A, Al-Hosaini, Mohamed M, Al-Harbi, Ali R, Alhoshani, Othman A, Al-Shabanah, Shakir Dekhal, Alsharari
Publikováno v:
BMC Complementary and Alternative Medicine
Background Liver diseases are major global health problems. Ginseng extract has antioxidant, immune-modulatory and anti-inflammatory activities. This study investigated the effect of ginseng extract on carbon tetrachloride (CCl4)-induced liver fibros
Alleviation of Aflatoxin B1-Induced Genomic Damage by Proanthocyanidins via Modulation of DNA Repair
Autor:
Saleh A, Bakheet, Ahmed M, Alhuraishi, Naif O, Al-Harbi, Khaled A, Al-Hosaini, Shakir D, Al-Sharary, Mohammed M, Attia, Ali R, Alhoshani, Othman A, Al-Shabanah, Mohammed M, Al-Harbi, Faisal, Imam, Sheikh F, Ahmad, Sabry M, Attia
Publikováno v:
Journal of biochemical and molecular toxicology. 30(11)
In order to study the mechanisms underlying the alleviation of aflatoxin B1-induced genomic damage by proanthocyanidins (PAs), we examined the modulation of oxidative DNA damage induced by aflatoxin B1 in PAs-pretreated animals. The effects of PAs on