Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ali Ozuer"'
Autor:
Arthur R. Frampton, William F. Goins, Paola Grandi, Ali Ozuer, Waris A. Shah, Hiroaki Uchida, Joseph C. Glorioso, Justus B. Cohen
Publikováno v:
Journal of Virology. 83:2951-2961
Both initial infection and cell-to-cell spread by herpes simplex virus type 1 (HSV-1) require the interaction of the viral glycoprotein D (gD) with an entry receptor on the cell surface. The two major HSV entry receptors, herpesvirus entry mediator (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0714f8ca4b4aa336399b236f3bad280
https://doi.org/10.1128/jvi.01449-08
https://doi.org/10.1128/jvi.01449-08
Autor:
David Krisky, Douglas Kondziolka, Darren Wolfe, John A. Goss, Joseph C. Glorioso, Anita M. Trichel, Michael Murphey-Corb, Clayton A. Wiley, E Kanal, Neal A. DeLuca, Ali Ozuer, Ajay Niranjan
Publikováno v:
Gene Therapy. 11:1675-1684
Malignant glioma is a fatal human cancer in which surgery, chemo- and radiation therapies are ineffective. Therapeutic gene transfer used in combination with current treatment methods may augment their effectiveness with improved clinical outcome. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df8e68c6d6146cdcdb87375e622a4d0
https://doi.org/10.1038/sj.gt.3302336
https://doi.org/10.1038/sj.gt.3302336
Autor:
Mohammad M. Ataai, William F. Goins, Darren Wolfe, Ali Ozuer, James B. Wechuck, Thomas Oligino, Joseph C. Glorioso
Publikováno v:
Biotechnology and Bioengineering. 79:112-119
Our work uses replication-defective genomic herpes simplex virus type-1 (HSV-1)-based vectors to transfer therapeutic genes into cells of the central nervous system and other tissues. Obtaining highly purified high-titer vector stocks is one of the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a138c7de9396bb335554b6680fb93a
https://doi.org/10.1002/bit.10310
https://doi.org/10.1002/bit.10310
Autor:
Justus B. Cohen, Steven K. Wendell, Arthur R. Frampton, Marianna Tsvitov, Ali Ozuer, Zoher Kapacee, Joseph C. Glorioso, William F. Goins, Waris A. Shah
Publikováno v:
Virology. 360(2)
Herpes simplex virus type 1 (HSV-1) entry into permissive cells involves attachment to cell-surface glycosaminoglycans (GAGs) and fusion of the virus envelope with the cell membrane triggered by the binding of glycoprotein D (gD) to cognate receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70756a9b3bc806843c945e6d0812f2a6
https://pubmed.ncbi.nlm.nih.gov/17157347
https://pubmed.ncbi.nlm.nih.gov/17157347
Autor:
Canping Jiang, Ali Ozuer, James B. Wechuck, Joseph C. Glorioso, Soraya Pornsuwan, Fazard Pourarian, David Krisky, Mohammad M. Ataai
Publikováno v:
Biotechnology and bioengineering. 95(1)
Metal catalyzed oxidation (MCO), which typically involves oxygen free radical generation, is an important pathway that leads to the deterioration of many biological molecules in solution. The occurrence of MCO in immobilized metal affinity chromatogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31151eb467d4e09365ad2463a3bc7f5
https://pubmed.ncbi.nlm.nih.gov/16673413
https://pubmed.ncbi.nlm.nih.gov/16673413
Autor:
Ali Ozuer, Darren Wolfe, Joseph C. Glorioso, David J. Fink, David Krisky, Joel S. Greenberger, William F. Goins, James B. Wechuck, M. Epperly, Julie P. Goff
In contrast to traditional drugs that generally act by altering existing gene product function, gene therapy aims to target the root cause of the disease by altering the genetic makeup of the cell to treat the disease. Researchers have adapted severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fea211178fb9489cc747cd9aba593428
https://doi.org/10.1385/1-59259-650-9:339
https://doi.org/10.1385/1-59259-650-9:339
Autor:
Joseph C. Glorioso, Mohammad M. Ataai, Darren Wolfe, William F. Goins, Brian Russell, James B. Wechuck, Ali Ozuer
Publikováno v:
Biotechnology progress. 18(3)
Herpes simplex virus type-1 (HSV-1) is a neurotrophic human pathogen that establishes life-long latency in the nervous system. Our laboratory has extensively engineered this virus to retain the ability to persist in neurons without expression of lyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a3bfadd6f41e4cb9579993b3912886
https://pubmed.ncbi.nlm.nih.gov/12052062
https://pubmed.ncbi.nlm.nih.gov/12052062
Autor:
Ali Ozuer, James B. Wechuck, Joseph C. Glorioso, Mohammad M. Ataai, Darren Wolfe, William F. Goins
Publikováno v:
Biotechnology and bioengineering. 77(6)
Herpes simplex virus type-1 (HSV-1) represents a unique vehicle for the introduction of foreign DNA to cells of a variety of tissues. The nature of the vector, the cell line used for propagation of the vector, and the culture conditions will signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1128ce3c39a7cf6138b4fcdd99f8f7b7
https://pubmed.ncbi.nlm.nih.gov/11807764
https://pubmed.ncbi.nlm.nih.gov/11807764
Publikováno v:
Molecular Therapy. 11:S293-S294
The long-term goal of our laboratory is to create replication defective HSV-1 based viral vectors that are suitable to support the clinical development of therapeutic gene delivery applications. In order to reach this goal three considerations that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::219cb314b5d8625d069b15c92668de4d
https://doi.org/10.1016/j.ymthe.2005.07.298
https://doi.org/10.1016/j.ymthe.2005.07.298