Biochemical recurrence after radical prostatectomy: Current status of its use as a treatment endpoint and early management strategies

Autor: Barrett Z McCormick, Ali M Mahmoud, Stephen B Williams, John W Davis

Publikováno v: Indian Journal of Urology, Vol 35, Iss 1, Pp 6-17 (2019)

Prostate cancer is one of the most common urological malignancies managed by a practicing urologist. Treatment strategies are varied, but radical prostatectomy (RP) remains a viable and commonly used option for many patients. A continuing challenge i

Externí odkaz: https://doaj.org/article/7837ba8a2fbe46388b673892e92cb070

The efficacy of simultaneous successive classic and variant infectious bronchitis virus vaccines versus circulating variant II Egyptian field virus

Autor: Amal A.M. Eid, Ali M. Mahmoud, Esraa E. Hamouda, Mohamed A. Metwally, Rasha M.M. Ezz-Eldin, Reham M. ElBakrey

Publikováno v: Open Veterinary Journal, Vol 14, Iss (1) (Zagazig Veterinary Conference), Pp 90-107 (2024)

Background: Being a ubiquitous, highly contagious virus with a continuous mutation and a large number of evolutions worldwide, the infectious bronchitis virus (IBV) continues to wreak problems among Egyptian chickens and generate economic losses. The

Externí odkaz: https://doaj.org/article/0640d372a9ad4e62beee16d9eafa5b54

Modeling Acquired Resistance to the Second-Generation Androgen Receptor Antagonist Enzalutamide in the TRAMP Model of Prostate Cancer

Autor: Magdalena Kostrzewa, Marco Presta, Luca Triggiani, Daniela Coltrini, Debora Paris, Viviana Marolda, Roberta Verde, Ali M. Mahmoud, Federica Maccarinelli, Gaia C. Ghedini, Marianna Cerasuolo, Roberto Ronca, Alessia Ligresti, Arianna Giacomini, Dominique Melck, Sara Rezzola

Publikováno v: Cancer research
Cerasuolo, M, Maccarinelli, F, Coltrini, D, Mokhtar, A, Marolda, V, Ghedini, G C, Rezzola, S, Giacomini, A, Triggiani, L, Kostrzewa, M, Verde, R, Paris, D, Melck, D, Presta, M, Ligresti, A & Ronca, R 2020, ' Modeling acquired resistance to the second-generation androgen receptor antagonist enzalutamide in the TRAMP model of prostate cancer ', Cancer Research, vol. 80, no. 7, 0, pp. 1564-1577 . https://doi.org/10.1158/0008-5472.CAN-18-3637

Enzalutamide (MDV3100) is a potent second-generation androgen receptor antagonist approved for the treatment of castration-resistant prostate cancer (CRPC) in chemotherapy-naïve as well as in patients previously exposed to chemotherapy. However, res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed7bd9cda3da743749fc546ed928950
https://doi.org/10.1158/0008-5472.can-18-3637

Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment

Autor: Silvia Gobbi, Alessandra Bisi, Letizia Pruccoli, Manuela Bartolini, Ignacio Moraleda, Serena Montanari, Marina Naldi, Sabrina Petralla, Barbara Monti, Alessia Ligresti, Isabel Iriepa, Alessandro Rabbito, Vincenzo Di Marzo, Ali M. Mahmoud, Federica Belluti, Andrea Tarozzi, Angela Rampa

Publikováno v: European journal of medicinal chemistry 178 (2019): 243–258. doi:10.1016/j.ejmech.2019.05.080
info:cnr-pdr/source/autori:Montanari, Serena; Mahmoud, Ali Mokhtar; Pruccoli, Letizia; Rabbito, Alessandro; Naldi, Marina; Petralla, Sabrina; Moraleda, Ignacio; Bartolini, Manuela; Monti, Barbara; Iriepa, Isabel; Belluti, Federica; Gobbi, Silvia; Di Marzo, Vincenzo; Bisi, Alessandra; Tarozzi, Andrea; Ligresti, Alessia; Rampa, Angela/titolo:Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment/doi:10.1016%2Fj.ejmech.2019.05.080/rivista:European journal of medicinal chemistry/anno:2019/pagina_da:243/pagina_a:258/intervallo_pagine:243–258/volume:178
European Journal of Medicinal Chemistry

To address the multifactorial nature of Alzheimer's Disease (AD), a multi-target-directed ligand approach was herein developed. As a follow-up of our previous studies, a small library of newly designed 2-arylbenzofuran derivatives was evaluated towar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa055218c5b73e3c7255d06e2d5ed41
https://doi.org/10.1016/j.ejmech.2019.05.080

Autism spectrum disorder (ASD)-associated mitochondrial deficits are revealed in children's platelets but unimproved by hyperbaric oxygen therapy

Autor: Mahmoud Aboulsaoud, Sameh S. Ali, Engy A. Abdel-Rahman, Eman Ahmed Zaky, Reham M. Elhossiny, Walaa Y. Youssef, Ali M. Mahmoud

Publikováno v: Free radical research. 55(1)

Mitochondrial and immune dysfunctions are often implicated in the aetiology of autism spectrum disorder (ASD). Here, we studied for the first time the relationship between ASD severity measures and mitochondrial respiratory rates in freshly isolated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fbe85a3c4e004f43c217578118a60c
https://pubmed.ncbi.nlm.nih.gov/33402007