Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ali M Berri"'
Autor:
Yimin Shen, Alana C. Conti, Ali M Berri, Kelly E. Bosse, Robin Roberts, Bruce A. Berkowitz, Kenan Sinan, Alexander Gow, Brandy L. Schneider, Karen Lins Childers, Waleed Eliwat, Scott C Lloyd, Robert H. Podolsky, Emma Graffice
Publikováno v:
GeroScience
Age-related impairments in spatial learning and memory often precede non-familial neurodegenerative disease. Ex vivo studies suggest that physiologic age-related oxidative stress in hippocampus area CA1 may contribute to prodromal spatial disorientat
Autor:
Michael Schneider, Robert H. Podolsky, Robin Roberts, Kenan Sinan, Thomas G. Cotter, Karen Lins Childers, Shasha Gao, Haohua Qian, Ali M Berri, Sarah L. Roche, Bruce A. Berkowitz, Emma Graffice, Lamis Harp
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The purpose of this study was to test the hypothesis that anti-oxidant and / or anti-inflammation drugs that suppress rod death in cyclic light-reared Pde6brd10 mice are also effective in dark-reared Pde6brd10 mice. Methods In untreated dark-
Autor:
Ali M Berri, Robin Roberts, Fatema Shafie-Khorassani, Emma Graffice, Bruce A. Berkowitz, Robert H. Podolsky, Kristin Dernay
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose In cyclic light-reared Pde6brd10 mice, rod cell oxidative stress contributes to the degenerative phenotype. Dark rearing Pde6brd10 mice slows but does not prevent atrophy. This suggests that outer retinal oxidative stress occurs in Pde6brd10
Autor:
Benjamin Farrell, Robert H. Podolsky, Emma Graffice, Bruce A. Berkowitz, Christopher Trepanier, Kristin Dernay, Hojun Lee, Ali M Berri, Fatema Shafie-Khorassani, Robin Roberts, Timothy S. Kern
Publikováno v:
Investigative Ophthalmology & Visual Science
Investigative ophthalmology & visual science, vol 59, iss 7
Investigative ophthalmology & visual science, vol 59, iss 7
Purpose New perspectives are needed to understand decades of contradictory reports on the neuroprotective effects of the Cav1.2 L-type calcium channel blocker d-cis-diltiazem in retinitis pigmentosa (RP) models. Here, we address, in vivo, the followi
Autor:
Ali M Berri, Geoffrey G. Murphy, Shaniya Maimaiti, Catherine Tran, Robert H. Podolsky, Nikita Khetarpal, Fatema Shafie-Khorassani, Bruce A. Berkowitz, Kristin Dernay, Johnny Y. Wu, John C. Gant, Brian M. Bennett, Olivier Thibault, Jacob Lenning, E. Mark Haacke, Robin Roberts
Publikováno v:
The FASEB Journal. 31:4179-4186
Hippocampus oxidative stress is considered pathogenic in neurodegenerative diseases, such as Alzheimer disease (AD), and in neurodevelopmental disorders, such as Angelman syndrome (AS). Yet clinical benefits of antioxidant treatment for these disease
Autor:
Bruce A. Berkowitz, Emma Graffice, Robin Roberts, Michael Schneider, Robert H. Podolsky, Ali M Berri, Lamis Harp, Karen Lins Childers, Kenan Sinan
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose To test the hypothesis that acutely correcting a sustained presence of outer retina free radicals measured in vivo in 24-month-old mice corrects their reduced visual performance. Methods Male C57BL/6J mice two and 24 months old were noninvasi
Autor:
Ali M Berri, Johnny Y. Wu, Fatema Shafie-Khorassani, Bruce A. Berkowitz, Nikita Khetarpal, Robin Roberts, Catherine Tran, Jacob Lenning, Kristin Dernay, Robert H. Podolsky
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose We identify noninvasive biomarkers that measure the severity of oxidative stress within retina layers in sodium iodate (SI)-atrophy vulnerable (C57BL/6 [B6]) and SI-atrophy resistant (129S6/SvEvTac [S6]) mice. Methods At 24 hours after admini