Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ali Loukaci"'
Autor:
Rachid Benhida, Wang-Qing Liu, Sylvie Dufour, Yves Lepelletier, Olivier Hermine, Bertrand Leforban, Renaud Grépin, Françoise Raynaud, Luc Demange, Christiane Garbay, Rafika Jarray, Matthieu Montes, Ali Loukaci, Gilles Pagès, Réda Hadj-Slimane, Lucia Borriello
Publikováno v:
Cancer Letters. 414:88-98
Neuropilin-1 (NRP-1) is an extra-cellular receptor for the main Vascular Endothelial Growth Factor over-expressed in tumour tissues, VEGF-A165. Consequently, NRP-1 is involved in angiogenesis and in tumour growth, and its over-expression is related t
Autor:
Ali Loukaci, Yves Lepelletier, Françoise Raynaud, Rafika Jarray, Huixiong Chen, Pascal Dao, Johanne Le Coq, Réda Hadj-Slimane, Daniel Lietha, Christiane Garbay
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:4552-4556
We report herein the synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK (focal adhesion kinase) inhibitors and the evaluation of their anti-angiogenic activity on HUVEC cells. Generally, the effects of these compounds on endothelial cel
Autor:
Verónica V. Valdivia, Aida Rivera, Jean-Louis Fourrey, Ali Loukaci, Leticia Quintero, Fernando Sartillo, Angélica Trujillo Hernández
Publikováno v:
Tetrahedron Letters. 46:6511-6514
Based on an unusual furanose ring opening of 1,2-O-isopropylidene pentofuranoside derivatives, a preparation scheme of a new series of furanopyrimidine nucleoside analogues has been devised.
Autor:
Jean Vacelet, Guilherme Muricy, Nicole Boury-Esnault, Jean-Paul Brouard, Michèle Guyot, Ali Loukaci
Publikováno v:
Biochemical Systematics and Ecology. 32:893-899
Chemical investigation of Oscarella lobularis and O. tuberculata confirmed the specific status of these two sibling species already suggested by allozyme electrophoresis and cytological analyses. O. tuberculata yielded alkylpyrrole-aldehydes and ster
Autor:
Eve Damiens, Cécile Debitus, Michèle Guyot, Laurent Meijer, Isabelle Le Saout, Mohammad Samadi, Sophie Leclerc, Ali Loukaci
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2001, 9, pp.3049-3054
Bioorganic and Medicinal Chemistry, Elsevier, 2001, 9, pp.3049-3054
The dual specificity CDC25 phosphatases dephosphorylate two inhibitory phospho-amino acids of cyclin-dependent kinases, a major family of cell cycle regulators. CDC25 inhibitors constitute new anti-mitotic agents with potential anticancer activity. W
Publikováno v:
Journal of Natural Products. 61:519-522
A new indole alkaloid (1) was isolated from the tunicate Dendrodoa grossularia. The structure was determined by spectroscopic means, particularly extensive 1D and 2D NMR studies and chemical transformation. X-Ray crystallographic analysis of 2, obtai
Autor:
Johanne Le Coq, Yves Lepelletier, Françoise Raynaud, Pascal Dao, Huixiong Chen, Réda Hadj-Slimane, Ali Loukaci, Rafika Jarray, Christiane Garbay, Daniel Lietha
Publikováno v:
ChemInform. 44
Compound (Ia) is found to show significant decrease of autophosphorylation of FAK in HUVEC cells.
Autor:
Christian Moreti, B. Richard, Monique Zèches-Hanrot, Ali Loukaci, Mahfoud Azoug, Louisette Le Men-Olivier, Jean-Marc Nuzillard
Publikováno v:
Phytochemistry. 39:1223-1228
During an investigation of the stem bark and leaves of Peschiera buchtieni , 34 alkaloids were isolated. Eight new alkaloids were obtained from the stem bark, N -methyl-pericyclivine, 18,19( R )-dihydroxycoronaridine, chloromethylene affinisinium, de
Autor:
Michèle Guyot, Ali Loukaci
Publikováno v:
Tetrahedron Letters. 35:6869-6872
Trikendiol 2 , an unusual red pigment, has been isolated from the sponge Trikentrion loeve . The structure was determined by the interpretation of spectral data. Trikendiol was shown to be anti-HIV-I.
Autor:
Ali Loukaci, Christiane Garbay, Yves Lepelletier, Réda Hadj-Slimane, Denis Biard, Lucia Borriello, Jérôme Larghero, Barbara Allain, Rafika Jarray, Françoise Raynaud
Publikováno v:
Biochimie. 93(10)
Using suppression subtractive hybridisation (SSH), we identified a hitherto unreported gene PHACTR-1 (Phosphatase Actin Regulating Protein-1) in Human Umbilical Vascular Endothelial Cells (HUVECs). PHACTR-1 is an actin and protein phosphatase 1 (PP1)