Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ali Khateb"'
Autor:
Ali Khateb, Anagha Deshpande, Yongmei Feng, Darren Finlay, Joo Sang Lee, Ikrame Lazar, Bertrand Fabre, Yan Li, Yu Fujita, Tongwu Zhang, Jun Yin, Ian Pass, Ido Livneh, Irmela Jeremias, Carol Burian, James R. Mason, Ronit Almog, Nurit Horesh, Yishai Ofran, Kevin Brown, Kristiina Vuori, Michael Jackson, Eytan Ruppin, Aniruddha J. Deshpande, Ze’ev A. Ronai
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Epigenetic changes are implicated in Acute myeloid leukemia (AML) tumorigenesis. Here, the authors show that the ubiquitin ligase RNF5 and its substrate RBBP4 contribute to AML development by regulating epigenetic-controlled transcription which deter
Externí odkaz:
https://doaj.org/article/906878f0ea8448bb9623f72fa90b2362
Autor:
Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian, Yu Fujita, Avinash Sahu, Raphy Zarecki, Kerrie Marie, Yongmei Feng, Ali Khateb, Dennie T. Frederick, Shiri K. Ashkenazi, Hyungsoo Kim, Eva Guijarro Perez, Chi-Ping Day, Rafael S. Segura Muñoz, Robert Schmaltz, Shibu Yooseph, Miguel A. Tam, Tongwu Zhang, Emily Avitan-Hersh, Lihi Tzur, Shoshana Roizman, Ilanit Boyango, Gil Bar-Sela, Amir Orian, Randal J. Kaufman, Marcus Bosenberg, Colin R. Goding, Bas Baaten, Mitchell P. Levesque, Reinhard Dummer, Kevin Brown, Glenn Merlino, Eytan Ruppin, Keith Flaherty, Amanda Ramer-Tait, Tao Long, Scott N. Peterson, Linda M. Bradley, Ze’ev A. Ronai
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
RNF5 is a ubiquitin ligase regulating ER stress response. Here the authors show that Rnf5 deficiency potentiates immune response against melanoma via altered microbiota, and isolate bacterial strains that confer the same phenotype to wild type mice.
Externí odkaz:
https://doaj.org/article/47e63127b17f4776963dab1e5a8faa8f
Autor:
Yu Fujita, Ali Khateb, Yan Li, Roberto Tinoco, Tongwu Zhang, Haggai Bar-Yoseph, Miguel A. Tam, Yehuda Chowers, Edmond Sabo, Shiran Gerassy-Vainberg, Elina Starosvetsky, Brian James, Kevin Brown, Shai S. Shen-Orr, Linda M. Bradley, Philippe A. Tessier, Ze’ev A. Ronai
Publikováno v:
Cell Reports, Vol 24, Iss 12, Pp 3296-3311.e6 (2018)
Summary: Inflammatory bowel disease (IBD) is prevalent, but the mechanisms underlying disease development remain elusive. We identify a role for the E3 ubiquitin ligase RNF5 in IBD. Intestinal epithelial cells (IECs) express a high level of RNF5, whi
Externí odkaz:
https://doaj.org/article/47d96a8a488349d4a35be97b7725e1e4
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplementary Table S1: Clinical information related to the PDX used in Fig1A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f75bcacd37d2cbb759a6ca9388ba6a3
https://doi.org/10.1158/1541-7786.22525866.v1
https://doi.org/10.1158/1541-7786.22525866.v1
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplemental Methods, Figures, Figure legends, Table and Movie Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058efe371d19894180d9514ec84de5fe
https://doi.org/10.1158/1541-7786.22525875
https://doi.org/10.1158/1541-7786.22525875
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplementary Movie S1 - 3D representation around the Y axis of A375 cell nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07124d82b28343054cafa9ec742a937b
https://doi.org/10.1158/1541-7786.22525872.v1
https://doi.org/10.1158/1541-7786.22525872.v1
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplementary Table S3: List of the genes that were identified by RNAseq to be significantly deregulated upon SPANX KD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e8529bdcf5a1c69e663a45ac85f1f9
https://doi.org/10.1158/1541-7786.22525860
https://doi.org/10.1158/1541-7786.22525860
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplementary Table S2: List of SPANX-interacting proteins identified by LC-MS/MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1844a5e06b8203e2496fdb3f50bbc4d8
https://doi.org/10.1158/1541-7786.22525863
https://doi.org/10.1158/1541-7786.22525863
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Supplementary Movie S2 - 3D representation around the X axis of A375 cell nucleus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60119b9cd9051aa56714235d7edefb69
https://doi.org/10.1158/1541-7786.22525869
https://doi.org/10.1158/1541-7786.22525869
Autor:
Ze'ev A. Ronai, Reinhard Dummer, Keith Flaherty, Meenhard Herlyn, Haguy Wolfenson, Ivan Topisirovic, Ola Larsson, Kevin Brown, Marzia Scortegagna, Ido Livneh, Emily Avitan-Hersh, Jeny Shklover, Brian James, Tongwu Zhang, Gao Zhang, Lea Feld, Mitchell P. Levesque, Dennie T. Frederick, Julia M. Martinez Gomez, Patrick Turko, Ali Khateb, Yongmei Feng, Bertrand Fabre, Ikrame Lazar
Mechanisms regulating nuclear organization control fundamental cellular processes, including the cell and chromatin organization. Their disorganization, including aberrant nuclear architecture, has been often implicated in cellular transformation. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126f024ba69cb8bfaab716e499645ccf
https://doi.org/10.1158/1541-7786.c.6544944.v1
https://doi.org/10.1158/1541-7786.c.6544944.v1