Catalyzed syntheses of novel series of spiro thiazolidinone derivatives with nano Fe2O3: spectroscopic, X-ray, Hirshfeld surface, DFT, biological and docking evaluations

Autor: Eslam M. Abbass, Ali El-Rayyes, Ali Khalil Ali, Ahmed F. El-Farargy, Anna Kozakiewicz-Piekarz, Ramadan M. Ramadan

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-25 (2024)

Abstract Twelve spiro thiazolidinone compounds (A–L) were synthesized via either conventional thermal or ultrasonication techniques using Fe2O3 nanoparticles. The modification of the traditional procedure by using Fe2O3 nanoparticles led to enhance

Externí odkaz: https://doaj.org/article/8649af806b8b4bd9b0fd30437af52448

Raising the Diversity of Ugi Reactions Through Selective Alkylations and Allylations of Ugi Adducts

Autor: Alaa Zidan, Abeer M. El-Naggar, Nour E. A. Abd El-Sattar, Ali Khalil Ali, Laurent El Kaïm

Publikováno v: Frontiers in Chemistry, Vol 7 (2019)

We report here selective Tsuji-Trost type allylation of Ugi adducts using a strategy based on the enhanced nucleophilicity of amide dianions. Ugi adducts derived from aromatic aldehydes were easily allylated at their peptidyl position with allyl acet

Externí odkaz: https://doaj.org/article/c59be7122df9414db0f8ec60a863d500

Regioselective Synthesis, Spectroscopic Characterization, and Computational Chemical Study of Spiro[Indoline-3,4’-Pyrazolo[3,4-b] Pyridine Derivatives as Agrochemical Agents

Autor: Sarah Ahmed El-Kaed, Nasser Abdelmoneim Ibrahim, Sameh A. Rizk, Ali Khalil Ali

Publikováno v: Polycyclic Aromatic Compounds. 42:5567-5584

Herein, new four-component domino reactions are described and utilized to synthesize spiro[indoline-3,4’-pyrazolo[3,4-b]pyridine derivatives via one-pot reaction. Different hydrazine derivatives su...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a31a2cea6a452f9947d31cd5ae22fa5
https://doi.org/10.1080/10406638.2021.1942083

Raising the Diversity of Ugi Reactions Through Selective Alkylations and Allylations of Ugi Adducts

Autor: Abeer M. El-Naggar, Ali Khalil Ali, Alaa Zidan, Laurent El Kaim, Nour E. A. Abd El-Sattar

Publikováno v: Frontiers in Chemistry, Vol 7 (2019)
Frontiers in Chemistry
Frontiers in Chemistry, Frontiers Media, 2019, 7 (20), ⟨10.3389/fchem.2019.00020⟩

International audience; We report here selective Tsuji-Trost type allylation of Ugi adducts using a strategy based on the enhanced nucleophilicity of amide dianions. Ugi adducts derived from aromatic aldehydes were easily allylated at their peptidyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe1b6dd9a359aaa23d0c9a5f8e6f7a04
https://www.frontiersin.org/article/10.3389/fchem.2019.00020/full

β-Lactam Synthesis through Diodomethane Addition to Amide Dianions

Autor: Ali Khalil Ali, Abeer M. El-Naggar, Mohamed A. Hassan, Alaa Zidan, Laurent El Kaim, Marie Cordier, Nour E. A. Abd El-Sattar, Julian Garrec

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2017, 56 (40), pp.12179-12183. ⟨10.1002/anie.201706315⟩

We present a novel route for the quick and easy synthesis of a broad range of β-lactams. The synthesis involves a [3+1] cyclization of amide dianions with diiodomethane. In contrast to the seminal work of Hirai et al. from 1979, the reaction proved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d395e95e98951d4f6b12d3ebc0b12b3
https://pubmed.ncbi.nlm.nih.gov/28741888