Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ali H Shilleh"'
Autor:
Federica Cuozzo, Katrina Viloria, Ali H. Shilleh, Daniela Nasteska, Charlotte Frazer-Morris, Jason Tong, Zicong Jiao, Adam Boufersaoui, Bryan Marzullo, Daniel B. Rosoff, Hannah R. Smith, Caroline Bonner, Julie Kerr-Conte, Francois Pattou, Rita Nano, Lorenzo Piemonti, Paul R.V. Johnson, Rebecca Spiers, Jennie Roberts, Gareth G. Lavery, Anne Clark, Carlo D.L. Ceresa, David W. Ray, Leanne Hodson, Amy P. Davies, Guy A. Rutter, Masaya Oshima, Raphaël Scharfmann, Matthew J. Merrins, Ildem Akerman, Daniel A. Tennant, Christian Ludwig, David J. Hodson
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114047- (2024)
Summary: Using 13C6 glucose labeling coupled to gas chromatography-mass spectrometry and 2D 1H-13C heteronuclear single quantum coherence NMR spectroscopy, we have obtained a comparative high-resolution map of glucose fate underpinning β cell functi
Externí odkaz:
https://doaj.org/article/2e924f2360b54e9dbc6f6da13e566a04
Autor:
Ali H. Shilleh, Holger A. Russ
Publikováno v:
Cells, Vol 12, Iss 5, p 698 (2023)
Cell replacement therapy using stem-cell-derived insulin-producing β-like cells (sBCs) has been proposed as a practical cure for patients with type one diabetes (T1D). sBCs can correct diabetes in preclinical animal models, demonstrating the promise
Externí odkaz:
https://doaj.org/article/cfcd5617ded74e5d9d11ae33749761a3
Autor:
Taylor M. Triolo, J. Quinn Matuschek, Roberto Castro-Gutierrez, Ali H. Shilleh, Shane P. M. Williams, Maria S. Hansen, Kristen McDaniel, Jessie M. Barra, Aaron Michels, Holger A. Russ
Publikováno v:
Cells, Vol 11, Iss 23, p 3845 (2022)
Type 1 diabetes is a polygenic disease that results in an autoimmune response directed against insulin-producing beta cells. PTPN2 is a known high-risk type 1 diabetes associated gene expressed in both immune- and pancreatic beta cells, but how genes
Externí odkaz:
https://doaj.org/article/c815f7b8019b402a86f01c7d17f644aa
Publikováno v:
Cell Metabolism. 34:193-196
Autor:
Katherine E. Santostefano, Fiona M. Docherty, Shane P.M. Williams, JaeAnn M. Dwulet, Maria S. Hansen, Richard K.P. Benninger, Kent Riemondy, Holger A. Russ, Ali H. Shilleh, Roberto Castro-Gutierrez, Taylor M. Triolo, Mark A. Wallet, Lucas H. Armitage, Clayton E. Mathews
Publikováno v:
Diabetes
Stem cell–derived β-like cells (sBC) carry the promise of providing an abundant source of insulin-producing cells for use in cell replacement therapy for patients with diabetes, potentially allowing widespread implementation of a practical cure. T
Autor:
Holger A. Russ, Richard K. P. Benninger, Taylor M. Triolo, Clayton E. Mathews, Mark A. Wallet, Katherine E. Santostefano, Lucas H. Armitage, Shane P. M. Williams, Maria S. Hansen, Ali H. Shilleh, JaeAnn M. Dwulet, Roberto Castro-Gutierrez, Kent A. Riemondy, Fiona M. Docherty
Stem cell derived beta-like cells (sBC) carry the promise of providing an abundant source of insulin-producing cells for use in cell replacement therapy for patients with diabetes, potentially allowing widespread implementation of a practical cure. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc22ee33eb5e88c90298fcf3096fbdf
https://doi.org/10.2337/figshare.15124980.v3
https://doi.org/10.2337/figshare.15124980.v3
Autor:
Stephan A. Ramos, John W. Kappler, Sheila I. Alizadeh, Loni Perrenoud, Prabha Yadav, Antonio Jimeno, Ali H. Shilleh, James Jaggers, John Morton, Holger A. Russ, Brendan Reed
Publikováno v:
J Allergy Clin Immunol
Background The thymus is a glandular organ that is essential for the formation of the adaptive immune system by educating developing T cells. The thymus is most active during childhood and involutes around the time of adolescence, resulting in a seve
Autor:
Maria A. Nagel, Boyd Timothy, Noah R. Johnson, Huntington Potter, Christina M. Coughlan, Ravi Mahalingam, Holger A. Russ, Christina N. Como, James E. Hassell, Cheryl L. Beseler, Anna M Burnet, Teresa Mescher, Andrew N. Bubak, D. Scott Schmid, Randall J. Cohrs, Colin Coleman, Ali H Shilleh
Publikováno v:
J Infect Dis
Background Varicella zoster virus (VZV) vasculopathy is characterized by persistent arterial inflammation leading to stroke. Studies show that VZV induces amyloid formation that may aggravate vasculitis. Thus, we determined if VZV central nervous sys