Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ali H, Zahalka"'
Autor:
Ali H. Zahalka, N. Patrik Brodin, Maria Maryanovich, Xizhe Wang, Kara L. Watts, Sandra Pinho, Chandan Guha, Paul S. Frenette
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract The prostate is a hormone-responsive organ where testicular androgens drive the proliferation and survival of prostatic cells, ensuring the development and functioning of this gland throughout life. Androgen deprivation therapy leads to apop
Externí odkaz:
https://doaj.org/article/6d8d0c1c0ea7404b996afc6c0621714d
Autor:
Maher Hanoun, Anna Arnal-Estapé, Maria Maryanovich, Ali H. Zahalka, Sarah K. Bergren, Chee W. Chua, Avigdor Leftin, Patrik N. Brodin, Michael M. Shen, Chandan Guha, Paul S. Frenette
Publikováno v:
Stem Cell Reports, Vol 12, Iss 6, Pp 1201-1211 (2019)
Summary: In the prostate, stem and progenitor cell regenerative capacities have been ascribed to both basal and luminal epithelial cells. Here, we show that a rare subset of mesenchymal cells in the prostate are epithelial-primed Nestin-expressing ce
Externí odkaz:
https://doaj.org/article/15df5a89ccbf40da95f5ba68658f136d
Autor:
Mengyu Yang, Atsushi Arai, Nobuyuki Udagawa, Toru Hiraga, Zhao Lijuan, Susumu Ito, Toshihisa Komori, Takeshi Moriishi, Koichi Matsuo, Kouji Shimoda, Ali H. Zahalka, Yasuhiro Kobayashi, Naoyuki Takahashi, Toshihide Mizoguchi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Bone marrow mesenchymal stem and progenitor cells (BM-MSPCs) maintain homeostasis of bone tissue by providing osteoblasts. Although several markers have been identified for labeling of MSPCs, these labeled cells still contain non-BM-MSPC pop
Externí odkaz:
https://doaj.org/article/cadaaf04dcdd4fafb0cada7bb88b1263
Autor:
Xizhe Wang, N. Patrik Brodin, Maria Maryanovich, Kara L. Watts, Ali H. Zahalka, Chandan Guha, Sandra Pinho, Paul S. Frenette
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Scientific Reports
Scientific Reports
The prostate is a hormone-responsive organ where testicular androgens drive the proliferation and survival of prostatic cells, ensuring the development and functioning of this gland throughout life. Androgen deprivation therapy leads to apoptosis of
Autor:
Emily Wiggins, Kara L. Watts, Evan Garden, Larkin Mohn, Ali H. Zahalka, A. Tewari, Stephen J. Freedland, Lauren E. Howard, Amanda M. DeHoedt, Jay Annam, Ilir Agalliu, Allison L. Reagan, Benjamin Eilender, Ethan Fram
Publikováno v:
Journal of Urology. 206
Autor:
Anna Arnal-Estapé, Chee W. Chua, Avigdor Leftin, Patrik Brodin, Ali H. Zahalka, Maher Hanoun, Chandan Guha, Sarah K. Bergren, Maria Maryanovich, Michael M. Shen, Paul S. Frenette
Publikováno v:
Stem Cell Reports, Vol 12, Iss 6, Pp 1201-1211 (2019)
Summary: In the prostate, stem and progenitor cell regenerative capacities have been ascribed to both basal and luminal epithelial cells. Here, we show that a rare subset of mesenchymal cells in the prostate are epithelial-primed Nestin-expressing ce
Autor:
John M. Greally, Ali H. Zahalka, Qiaozhi Wei, Avi Ma'ayan, Paul S. Frenette, Zichen Wang, Masako Suzuki, Maria Maryanovich, Chunliang Xu, Cristian Cruz, Sandra Pinho, Philip E. Boulais, Daniel K. Borger, Fumio Nakahara
Publikováno v:
Nature Cell Biology. 21:560-567
Haematopoietic stem cells (HSCs) are maintained by bone marrow niches in vivo1,2, but the ability of niche cells to maintain HSCs ex vivo is markedly diminished. Expression of niche factors by Nestin-GFP+ mesenchymal-derived stromal cells (MSCs) is d
Autor:
Ali H. Zahalka, Paul S. Frenette
Publikováno v:
Nat Rev Cancer
The contribution of nerves to the pathogenesis of malignancies has emerged as an important component of the tumour microenvironment. Recent studies have shown that peripheral nerves (sympathetic, parasympathetic and sensory) interact with tumour and
Autor:
Noboru Asada, Sandra Pinho, Xizhe Wang, Avigdor Leftin, Paul S. Frenette, Maria Maryanovich, Fumio Nakahara, Halley Pierce, Qiaozhi Wei, Paul Ciero, Jianing Xu, Ali H. Zahalka
Publikováno v:
Nature medicine
Nat Med
Nat Med
Aging of hematopoietic stem cells (HSCs) is associated with a decline in their regenerative capacity and multilineage differentiation potential, contributing to the development of blood disorders. The bone marrow microenvironment has recently been su
Autor:
Ali H. Zahalka, Ilir Agalliu, Paul S. Frenette, Larkin Mohn, Wilson Lin, Kara L. Watts, Ethan Fram
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:Recent evidence from pre-clinical models of prostate cancer (PCa) suggests that disruption of adrenergic signaling by beta-adrenergic receptor blockade inhibits PCa prog...