Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Ali G. Turhan"'
Autor:
Matthias Huyghe, Christophe Desterke, Jusuf Imeri, Nathan Belliard, Diana Chaker, Noufissa Oudrirhi, Hudson Bezerra, Ali G. Turhan, Annelise Bennaceur-Griscelli, Frank Griscelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
PurposeThe ability to generate natural killer (NK) cells from induced pluripotent stem cells (iPSCs) has given rise to new possibilities for the large-scale production of homogeneous immunotherapeutic cellular products and opened new avenues towards
Externí odkaz:
https://doaj.org/article/9c8458838df842599daa98e2530209af
Autor:
Seda Baykal, Maud Voldoire, Christophe Desterke, Nathalie Sorel, Emilie Cayssials, Hyacinthe Johnson-Ansah, Agnes Guerci-Bresler, Annelise Bennaceur-Griscelli, Jean-Claude Chome, Ali G. Turhan
Publikováno v:
Turkish Journal of Hematology, Vol 40, Iss 2, Pp 101-117 (2023)
Objective: Chronic myeloid leukemia (CML) is a disease caused by the acquisition of BCR-ABL1 fusion in hematopoietic stem cells. In this study, we focus on the oncofetal ENOX2 protein as a potential secretable biomarker in CML. Materials and Methods
Externí odkaz:
https://doaj.org/article/f24131ac61f244a59ac5e89c9052cb12
Autor:
Jusuf Imeri, Paul Marcoux, Matthias Huyghe, Christophe Desterke, Daianne Maciely Carvalho Fantacini, Frank Griscelli, Dimas T. Covas, Lucas Eduardo Botelho de Souza, Annelise Bennaceur Griscelli, Ali G. Turhan
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
During the last two decades, the introduction of tyrosine kinase inhibitors (TKIs) to the therapy has changed the natural history of CML but progression into accelerated and blast phase (AP/BP) occurs in 3-5% of cases, especially in patients resistan
Externí odkaz:
https://doaj.org/article/0c3adcf33f5940548d7c01d3745fbbde
Autor:
Paul Marcoux, Jin Wook Hwang, Christophe Desterke, Jusuf Imeri, Annelise Bennaceur-Griscelli, Ali G. Turhan
Publikováno v:
Cells, Vol 12, Iss 24, p 2847 (2023)
REarranged during Transfection (RET) oncogenic rearrangements can occur in 1–2% of lung adenocarcinomas. While RET-driven NSCLC models have been developed using various approaches, no model based on patient-derived induced pluripotent stem cells (i
Externí odkaz:
https://doaj.org/article/92037f83fb494f4290a5d9f921a780cb
Autor:
Jusuf Imeri, Christophe Desterke, Paul Marcoux, Diana Chaker, Noufissa Oudrhiri, Xavier Fund, Jamila Faivre, Annelise Bennaceur-Griscelli, Ali G. Turhan
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The classical natural history of chronic myeloid leukemia (CML) has been drastically modified by the introduction of tyrosine kinase inhibitor (TKI) therapies. TKI discontinuation is currently possible in patients in deep molecular responses, using s
Externí odkaz:
https://doaj.org/article/8211119622e94c1fbfd0a5d82be2c842
Autor:
Lara Boucher, Nathalie Sorel, Christophe Desterke, Mélanie Chollet, Laura Rozalska, Maria Pilar Gallego Hernanz, Emilie Cayssials, Anna Raimbault, Annelise Bennaceur-Griscelli, Ali G. Turhan, Jean-Claude Chomel
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15441 (2023)
Acute myeloid leukemia (AML) with BCR::ABL1 has recently been recognized as a distinct subtype in international classifications. Distinguishing it from myeloid blast crisis chronic myeloid leukemia (BC-CML) without evidence of a chronic phase (CP), r
Externí odkaz:
https://doaj.org/article/57e15394f26d4bfb96196cb0714b57cb
Autor:
Gladys Telliam, Christophe Desterke, Jusuf Imeri, Radhia M’kacher, Noufissa Oudrhiri, Estelle Balducci, Micheline Fontaine-Arnoux, Hervé Acloque, Annelise Bennaceur-Griscelli, Ali G. Turhan
Publikováno v:
Cancers, Vol 15, Iss 9, p 2594 (2023)
Methods: We used a patient-specific induced pluripotent stem cell (iPSC) line treated with the mutagenic agent N-ethyl-N-nitrosourea (ENU). Genomic instability was validated using γ-H2AX and micronuclei assays and CGH array for genomic events. Resul
Externí odkaz:
https://doaj.org/article/5774e227ee2a41019ef7112028527b5f
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-19 (2021)
Abstract Background The worldwide pandemic caused by the SARS-CoV-2 virus is characterized by significant and unpredictable heterogeneity in symptoms that remains poorly understood. Methods Transcriptome and single cell transcriptome of COVID19 lung
Externí odkaz:
https://doaj.org/article/2ba4ddaf15d14a53af9f1796e6f0cfe5
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-20 (2021)
Abstract Background During aging, hematopoietic stem cells (HSC) lose progressively both their self-renewal and differentiation potential. The precise molecular mechanisms of this phenomenon are not well established. To uncover the molecular events u
Externí odkaz:
https://doaj.org/article/cb024e63dc2a44b9bf9c6125d831b5e9
Autor:
Christophe Desterke, Frank Griscelli, Jusuf Imeri, Paul Marcoux, Thomas Lemonnier, Theodoros Latsis, Ali G. Turhan, Annelise Bennaceur‐Griscelli
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 4, Pp 568-571 (2021)
Abstract The use of mesenchymal stem cells (MSC) derived from several sources has been suggested as a major anti‐inflammation strategy during the recent outbreak of coronavirus‐19 (COVID‐19). As the virus enters the target cells through the rec
Externí odkaz:
https://doaj.org/article/41ee52e41d62470b8c71a80bf35c4b1d