Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ali El-Hadi Makki"'
Autor:
Viktoriya Morozova, Leah S. Cohen, Ali El-Hadi Makki, Alison Shur, Guillermo Pilar, Abdeslem El Idrissi, Alejandra D. Alonso
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The microtubule associated protein tau is mainly found in the cell’s cytosol but recently it was also shown in the extracellular space. In neurodegenerative diseases, like Alzheimer’s disease (AD), pathological tau spreads from neuron to neuron e
Externí odkaz:
https://doaj.org/article/51cbe79388f242f68e00cd5f3f4bb638
Autor:
Viktoriya Morozova, Jorge Baquero, Ali El-Hadi Makki, Alejandra del C. Alonso, Gamage Aruggoda, Frida E. Kleiman, Martha Ordonez, Sophia Varriano, Michael R. Murphy, Pawel Kuczaj, Devon Lundine
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
While nuclear tau plays a role in DNA damage response (DDR) and chromosome relaxation, the mechanisms behind these functions are not fully understood. Here, we show that tau forms complex(es) with factors involved in nuclear mRNA processing such as t