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Akademický článek

Antimicrobial Activity of Novel Ni(II) and Zn(II) Complexes with (E)-2-((5-Bromothiazol-2-yl)imino)methyl)phenol Ligand: Synthesis, Characterization and Molecular Docking Studies

Autor: Inas Al-Qadsy, Waseem Sharaf Saeed, Ahmad Abdulaziz Al-Owais, Abdelhabib Semlali, Ali Alrabie, Lena Ahmed Saleh Al-Faqeeh, Mohammed ALSaeedy, Arwa Al-Adhreai, Abdel-Basit Al-Odayni, Mazahar Farooqui

Publikováno v: Antibiotics, Vol 12, Iss 11, p 1634 (2023)

In order to address the challenges associated with antibiotic resistance by bacteria, two new complexes, Ni(II) and Zn(II), have been synthesized using the conventional method based on Schiff base ligand (E)-2-((5-bromothiazol-2-yl) imino) methyl) ph

Externí odkaz: https://doaj.org/article/c3720373f4c846af98259db80ba6eee6

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Akademický článek

Design and synthesis of novel enantiopure Bis(5-Isoxazolidine) derivatives: insights into their antioxidant and antimicrobial potential via in silico drug-likeness, pharmacokinetic, medicinal chemistry properties, and molecular docking studies

Autor: Arwa AL-Adhreai, Mohammed ALSaeedy, Ali Alrabie, Inas Al-Qadsy, Sam Dawbaa, ZabnAllah M. Alaizeri, Hisham A. Alhadlaq, Abdulrahman Al-Kubati, Maqusood Ahamed, Mazahar Farooqui

Publikováno v: Heliyon, Vol 8, Iss 6, Pp e09746- (2022)

A series of novel compounds, mono-5-isoxazolidines, and bis (5-isoxazolidines) derivatives, were prepared as bicycloadducts. The new series of isoxazolidines were designed and synthesized via 1,3-dipolar cycloaddition reaction of nitrones with 3,9-Di

Externí odkaz: https://doaj.org/article/a641dc20f54e4cf8a98429553a49aca8

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Akademický článek

Supercritical carbon dioxide extraction of Triognella foenum graecum Linn seeds: Determination of bioactive compounds and pharmacological analysis

Autor: Ola Basa'ar, Samreen Fatema, Ali Alrabie, Mohammed Mohsin, Mazahar Farooqui

Publikováno v: Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 12, Pp 1085-1091 (2017)

Objective: To investigate the effect of temperature and pressure on supercritical CO2 extraction of Triognella foenum graecum Linn seeds, to determine the optimal condition which leads to highest percentage of the accumulative yield and revealing the

Externí odkaz: https://doaj.org/article/ee85db8d8ee6494b9f701275599c352d

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Akademický článek

Synthesis, Characterization, Single-Crystal X-ray Structure and Biological Activities of [(Z)-N′-(4-Methoxybenzylidene)benzohydrazide–Nickel(II)] Complex

Autor: Inas Al-Qadsy, Abdel-Basit Al-Odayni, Waseem Sharaf Saeed, Ali Alrabie, Arwa Al-Adhreai, Lena Ahmed Saleh Al-Faqeeh, Prem Lama, Abdulaziz Ali Alghamdi, Mazahar Farooqui

Publikováno v: Crystals, Vol 11, Iss 2, p 110 (2021)

(Z)-N′-(4-methoxybenzylidene)benzohydrazide (HL) and its Ni(II) complex (Ni(II)-2L) were synthesized using eco-friendly protocols. The single X-ray crystal structure of Ni(II)-2L was solved. Moreover, the structural properties were evaluated using

Externí odkaz: https://doaj.org/article/7d0621d51d864426807fda9a7a24e26f

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An integrative GC–MS and LC–MS metabolomics platform determination of the metabolite profile of Bombax ceiba L. root, and in silico & in vitro evaluation of its antibacterial & antidiabetic activities

Autor: Ali Alrabie, Nabeel Abdullah Alrabie, Mohammed AlSaeedy, Arwa Al-Adhreai, Inas Al-Qadsy, Sultan A. Al-Horaibi, ZabnAllah M. Alaizeri, Hisham A. Alhadlaq, Maqusood Ahamed, Mazahar Farooqui

Publikováno v: Natural Product Research. :1-6

The Bombax ceiba L. tree is a member of the family Bombacaceae and the genus Bombax. Both Chinese and Indian traditional medicine have made extensive use of it in the treatment of sickness. Its chemical composition is still a mystery. B. ceiba roots

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75785154a0ba01fd10bc52cf50a2a703
https://doi.org/10.1080/14786419.2022.2149519

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Martynia annua safety and efficacy: heavy metal profile, in silico and in vitro approaches on antibacterial and antidiabetic activities

Autor: Ali Alrabie, Nabeel Abdullah Al-Rabie, Mohammed AL Saeedy, Arwa AL Adhreai, Inas Al-Qadsy, Mazahar Farooqui

Publikováno v: Natural Product Research. 37:1016-1022

Liquid Chromatography-Mass Spectrometry (LC-MS) analysis of methanol extract of Martynia annua seed revealed the presence of haploperozide and austricine. For safety, heavy metals content investigation of plant powder using the Inductively Coupled Pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6b2a8ee3afed77a7b1644f752efc5f
https://doi.org/10.1080/14786419.2022.2097227

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Phytochemical Screening, GC-MS Analysis, Molecular Docking Study and Evaluation of Antioxidant and Antimicrobial Activity of Sapindus emarginatus Seed Kernel

Autor: Ali Alrabie, Arwa Al-Dhreai, Inas Al-Qadsy, Vidya Pradhan, Mazahar Farooqui

Publikováno v: Research Journal of Pharmacy and Technology. :2117-2121

Objectives: The present study was designed to identify and screen phytochemicals present in methanolic extract of Sapindus emarginatus seed kernel, to evaluate its antimicrobial and antioxidant activity and to search for dihydropteroate synthase (3TY

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fda2d5cc16ca0e33f6ec935e03c85fbf
https://doi.org/10.52711/0974-360x.2022.00351

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Spectrophotometric determination of Zr(IV), Hg(II) and U(VI) in solution with their analytical applications: Structural characterization and molecular docking of the solid complexes

Autor: Walaa H. El-Shwiniy, Sameh I. El-Desoky, Ali Alrabie, Badr Abd El-wahaab

Publikováno v: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 279

Spectrophotometry was used to determine trace amounts of Zirconium(IV), Mercury(II) and Uranium(VI) in environmental, biological, pharmaceutical and industrial samples. The determination depend on the complexation reactions between albendazole reagen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaed18b85ac9506c869d9433ca8aa985
https://pubmed.ncbi.nlm.nih.gov/35609395

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