Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ali Al-Hakim"'
Autor:
Ali Al-Hakim PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 27 (2021)
Heparin is one of the most widely used drugs in the world. It has been described as a lifesaving drug due to its roles in treating many serious diseases and illnesses including kidney dialysis, surgery, cardiac-invasive, heart attack, cardiac arrhyth
Externí odkaz:
https://doaj.org/article/b74e9d14f425465bb54f693717e864db
Autor:
Ali Al-Hakim, Laith, Hassan, Shahizan
Publikováno v:
Journal of Business Economics and Management. 17(1):109-124
Externí odkaz:
https://www.ceeol.com/search/article-detail?id=366427
Autor:
Laith Ali Al-Hakim, Shahizan Hassan
Publikováno v:
Journal of Business Economics and Management, Vol 17, Iss 1 (2016)
The present study aims to examine the relationship among core requirements of knowledge management implementation, innovation, and organizational performance in the Iraqi mobile telecommunications sector. A questionnaire was conducted on mobile compa
Externí odkaz:
https://doaj.org/article/f1b31e0c0135400980ecac129c7d7269
Autor:
Pearle Torralba, Moheb Nasr, Elaine Gray, Roger L. Williams, Gyöngyi Gratzl, Edward K. Chess, Kristian Johansen, David A. Keire, Ali Al-Hakim, Anita Y. Szajek, Janet Woodcock, Christian Viskov, Jian Liu, Robert J. Linhardt, Zachary Shriver, Barbara Mulloy, Tina S. Morris, Wesley E. Workman
Publikováno v:
Nature Biotechnology. 34:625-630
The contamination of the widely used lifesaving anticoagulant drug heparin in 2007 has drawn renewed attention to the challenges that are associated with the characterization, quality control and standardization of complex biological medicines from n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9cafb0f3ae34d6bdb743c8a9ee29a09
https://doi.org/10.1038/nbt.3606
https://doi.org/10.1038/nbt.3606
Autor:
Ping Zhao, Pengfei Song, Zhe Tang, Qi Liu, Yuzhuo Pan, Lijun Zhang, Whitney S. Helms, Gideon M. Blumenthal, Sean Khozin, Margaret E. Brower, Hong Zhao, Patricia Keegan, Karen Boyd, Emily Fox, R. Pazdur, Robert Justice, Shenghui Tang, Donghao Lu, Ali Al Hakim, Ruby Leong
Publikováno v:
Clinical Cancer Research. 21:2436-2439
On April 29, 2014, the FDA granted accelerated approval to ceritinib (ZYKADIA; Novartis Pharmaceuticals Corporation), a breakthrough therapy-designated drug, for the treatment of patients with anaplastic lymphoma kinase (ALK)–positive, metastatic n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7390406d0fe33478b6f3ec9850289280
https://doi.org/10.1158/1078-0432.ccr-14-3157
https://doi.org/10.1158/1078-0432.ccr-14-3157
Autor:
Timothy K. Toby, Ali Al-Hakim, Hongping Ye, Houman Ghasriani, David A. Keire, Richard E. Kolinski, Cynthia D. Sommers, Wei Ye, Michael L. Trehy, Lucinda F. Buhse
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 85:99-107
During the 2007-2008 heparin crisis it was found that the United States Pharmacopeia (USP) testing monograph for heparin sodium or low molecular weight heparins did not detect the presence of the contaminant, oversulfated chondroitin sulfate (OSCS).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbad72ba54f38f230be0c60a225f39db
https://doi.org/10.1016/j.jpba.2013.06.033
https://doi.org/10.1016/j.jpba.2013.06.033
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. :42-50
Previously, the FDA validated a method to assess the structure and composition of heparin products by separating and quantifying disaccharide level digests by reverse-phase-ion-pairing liquid chromatography (RPIP-HPLC) coupled to a low resolution and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8fc2d731419cd7f035b5faa1ab2b8b
https://doi.org/10.1016/j.jpba.2012.04.033
https://doi.org/10.1016/j.jpba.2012.04.033
Autor:
Hongping Ye, Ali Al-Hakim, Cynthia D. Sommers, Lucinda F. Buhse, Moheb Nasr, David A. Keire, Richard E. Kolinski
Publikováno v:
Analytical and Bioanalytical Chemistry. 401:2445-2454
We evaluated polyacrylamide gel electrophoresis (PAGE) and size exclusion chromatography coupled with multi-angle laser light scattering (SEC-MALLS) approaches to determine weight-average molecular weight (M w) and polydispersity (PD) of heparins. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9a56edf3e9b18db53e929e9f32fddc
https://doi.org/10.1007/s00216-011-5362-z
https://doi.org/10.1007/s00216-011-5362-z
Autor:
Shankar Srinivasan, Richard D. Wood, Moheb Nasr, William J. Welsh, David A. Keire, Qingda Zang, Syed Haque, Dinesh P. Mital, Michael L. Trehy, Christine M. V. Moore, Ali Al-Hakim, Lucinda F. Buhse
Publikováno v:
Analytical and Bioanalytical Chemistry. 401:939-955
Chemometric analysis of a set of one-dimensional (1D) (1)H nuclear magnetic resonance (NMR) spectral data for heparin sodium active pharmaceutical ingredient (API) samples was employed to distinguish USP-grade heparin samples from those containing ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c80dd725cd4fec84677f4f2c1addfa3
https://doi.org/10.1007/s00216-011-5155-4
https://doi.org/10.1007/s00216-011-5155-4
Autor:
Michael L. Trehy, David A. Keire, Qingda Zang, Moheb Nasr, Richard D. Wood, Ali Al-Hakim, William J. Welsh, Lucinda F. Buhse, Christine M. V. Moore
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 54:1020-1029
Heparin is a naturally produced, heterogeneous compound consisting of variably sulfated and acetylated repeating disaccharide units. The structural complexity of heparin complicates efforts to assess the purity of the compound, especially when differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25c8e4b23441e7b34aae7d4f8bb5a76
https://doi.org/10.1016/j.jpba.2010.12.008
https://doi.org/10.1016/j.jpba.2010.12.008