Wilson's Disease in Saudi Arabia: Report of a Saudi Arab Family

Autor: Fateh El-Rahman E. Ahmad, M. B. Satti, Ali A. El-Tayeb

Publikováno v: Annals of Saudi Medicine. 11:605-610

A Saudi family with Wilson's disease (hepatolenticular degeneration) is described. The index case presented with anicteric hepatitis and hydrops of the gallbladder. Neurological involvement appeared later. The diagnosis of Wilson's disease was based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886bf9bd340e91c358914bcfb27ea875
https://doi.org/10.5144/0256-4947.1991.605

Rhinosporidiosis of the male urethra

Autor: Farukh Qureshi, Mahmoud S. Abdulmannan, Ali A. El-Tayeb, Ayman Gabr, Syed Qadri, Hussein Al-Qahtani

Publikováno v: Annals of Saudi medicine. 24(4)

Rhinosporidiosis is a benign condition with minimal systemic effects. The organisms are limited to the polyps; regional lymph nodes and adjacent tissues are not involved. The lymph nodes and tissues cause pressure and obstructive symptoms when they e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85197900e8e8093cd4f90ba2d4434b8
https://pubmed.ncbi.nlm.nih.gov/15387501

Preparation and preliminary evaluation of a tritium-labeled allosteric P2X4 receptor antagonist.

Autor: Nagel J; PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Pharmaceutical & Medicinal Chemistry, An der Immenburg 4, Bonn, 53121, Germany., Törmäkangas O; Orion Pharma, Orion Corporation, Tengströminkatu 8, FI-20360 Turku, and Orionintie 1A, Espoo, FI- 02200, Finland., Kuokkanen K; Orion Pharma, Orion Corporation, Tengströminkatu 8, FI-20360 Turku, and Orionintie 1A, Espoo, FI- 02200, Finland., El-Tayeb A; PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Pharmaceutical & Medicinal Chemistry, An der Immenburg 4, Bonn, 53121, Germany., Messinger J; Orion Pharma, Orion Corporation, Tengströminkatu 8, FI-20360 Turku, and Orionintie 1A, Espoo, FI- 02200, Finland., Abdelrahman A; PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Pharmaceutical & Medicinal Chemistry, An der Immenburg 4, Bonn, 53121, Germany., Bous C; PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Pharmaceutical & Medicinal Chemistry, An der Immenburg 4, Bonn, 53121, Germany., Schiedel AC; PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Pharmaceutical & Medicinal Chemistry, An der Immenburg 4, Bonn, 53121, Germany., Müller CE; PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Pharmaceutical & Medicinal Chemistry, An der Immenburg 4, Bonn, 53121, Germany. christa.mueller@uni-bonn.de.

Publikováno v: Purinergic signalling [Purinergic Signal] 2024 Dec; Vol. 20 (6), pp. 645-656. Date of Electronic Publication: 2024 May 25.

2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes.

Autor: Bhattarai S; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Pippel J; Institute of Bioanalytical Chemistry, Center for Biotechnology and Biomedicine, Leipzig University, Deutscher Platz 5, D-04103 Leipzig, Germany., Scaletti E; Institute of Bioanalytical Chemistry, Center for Biotechnology and Biomedicine, Leipzig University, Deutscher Platz 5, D-04103 Leipzig, Germany., Idris R; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Freundlieb M; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Rolshoven G; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Renn C; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Lee SY; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Abdelrahman A; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Zimmermann H; Institute of Cell Biology and Neuroscience, Goethe-University, D-60438 Frankfurt am Main, Germany., El-Tayeb A; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Müller CE; PharmaCenter Bonn, Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Sträter N; Institute of Bioanalytical Chemistry, Center for Biotechnology and Biomedicine, Leipzig University, Deutscher Platz 5, D-04103 Leipzig, Germany.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Mar 26; Vol. 63 (6), pp. 2941-2957. Date of Electronic Publication: 2020 Feb 28.

Substituted 4-phenylthiazoles: Development of potent and selective A 1 , A 3 and dual A 1 /A 3 adenosine receptor antagonists.

Autor: Abdelrahman A; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany; Pharma Center Bonn, University of Bonn, Brühlerstr. 7, D-53121, Bonn, Germany., Yerande SG; Department of Medicinal Chemistry, B. V. Patel Pharmaceutical Education and Research Development (PERD) Centre, Ahmedabad, 380 054, Gujarat, India., Namasivayam V; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany; Pharma Center Bonn, University of Bonn, Brühlerstr. 7, D-53121, Bonn, Germany., Klapschinski TA; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany; Pharma Center Bonn, University of Bonn, Brühlerstr. 7, D-53121, Bonn, Germany., Alnouri MW; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany., El-Tayeb A; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany; Pharma Center Bonn, University of Bonn, Brühlerstr. 7, D-53121, Bonn, Germany., Müller CE; Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121, Bonn, Germany; Pharma Center Bonn, University of Bonn, Brühlerstr. 7, D-53121, Bonn, Germany. Electronic address: christa.mueller@uni-bonn.de.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2020 Jan 15; Vol. 186, pp. 111879. Date of Electronic Publication: 2019 Nov 15.