Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ali A Zarrin"'
Autor:
Nisha Rathore, Sree Ranjani Ramani, Homer Pantua, Jian Payandeh, Tushar Bhangale, Arthur Wuster, Manav Kapoor, Yonglian Sun, Sharookh B Kapadia, Lino Gonzalez, Ali A Zarrin, Alison Goate, David V Hansen, Timothy W Behrens, Robert R Graham
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007427 (2018)
Paired Immunoglobulin-like Type 2 Receptor Alpha (PILRA) is a cell surface inhibitory receptor that recognizes specific O-glycosylated proteins and is expressed on various innate immune cell types including microglia. We show here that a common misse
Externí odkaz:
https://doaj.org/article/841cdb67d7d14a16be25d2e1fb374eac
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13992 (2010)
The 5' end of the IgH locus contains a cluster of DNaseI hypersensitive sites, one of which (HS1) was shown to be pro-B cell specific and to contain binding sites for the transcription factors PU.1, E2A, and Pax5. These data as well as the location o
Externí odkaz:
https://doaj.org/article/52108ed4520d4e0b98e944c1d618696c
Autor:
Ali A. Zarrin, Renato C. Monteiro
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/9b09c65a92454f1d8c4695ccaa9bf1a9
Autor:
Katherine Bao, Juan Zhang, Alexis Scherl, James Ziai, Azi Hadadianpour, Daqi Xu, Christopher Dela Cruz, John Liu, Yuxin Liang, Lucinda Tam, Cesar A. Corzo, Merone Roose-Girma, Soren Warming, Zora Modrusan, Wyne P. Lee, Kam Hon Hoi, Ali A. Zarrin
Publikováno v:
The Journal of Immunology. 208:2632-2642
Genetic and environmental cues shape the evolution of the B cell Ig repertoire. Activation-induced cytidine deaminase (AID) is essential to generating Ig diversity through isotype class switching and somatic mutations, which then directly influence c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7df2e88b7d04fa4a050bba87261356c
https://doi.org/10.4049/jimmunol.2101193
https://doi.org/10.4049/jimmunol.2101193
Autor:
Renato C. Monteiro, Ali A. Zarrin
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed7a1ab433612647af5c25b14ab52e2
https://www.frontiersin.org/articles/10.3389/fimmu.2020.633686/full
https://www.frontiersin.org/articles/10.3389/fimmu.2020.633686/full
Publikováno v:
Toxicology and applied pharmacology. 418
Tumor progression locus 2 (Tpl2, gene name MAP3K8), a mitogen-activated protein kinase, is widely expressed in immune and non-immune cells to integrate tumor necrosis factor (TNF), toll-like receptors (TLRs), and interleukin-1 (IL1) receptor signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120f3fe712dac9cd5e0e653519131737
https://pubmed.ncbi.nlm.nih.gov/33722668
https://pubmed.ncbi.nlm.nih.gov/33722668
Autor:
Lucinda Tam, Annemarie Lekkerkerker, Jeffrey Eastham-Anderson, Melanie Domeyer, Brent S. McKenzie, Azadeh Hadadianpour, Eugene Varfolomeev, Arna Katewa, Steven Do, A. Francesca Setiadi, Wyne P. Lee, Joy Drobnick, Andres Paler-Martinez, Rajita Pappu, Katherine Bao, Marian C. Bryan, Alfred Wong, James J. Crawford, Cesar A. Corzo, Vida Asghari, Sha Klabunde, Vladimir Ramirez-Carrozi, Jodie Pang, Jason A. Hackney, Hans Brightbill, Christopher Dela Cruz, Ross Francis, Yonglian Sun, Merone Roose-Girma, Claire Emson, Wendy B. Young, Michael J. Townsend, James R. Kiefer, Cary D. Austin, Swathi Sujatha-Bhaskar, Emily Hunley, Nico Ghilardi, Daqi Xu, Søren Warming, Kate Senger, Zhiyu Huang, Vivian W. C. Lau, Domagoj Vucic, Ali A. Zarrin, Eric Suto
Publikováno v:
Science signaling. 13(634)
The dysregulation of multiple signaling pathways, including those through endosomal Toll-like receptors (TLRs), Fc gamma receptors (FcγR), and antigen receptors in B cells (BCR), promote an autoinflammatory loop in systemic lupus erythematosus (SLE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df56c99041e31c3d42be9d115b0561d
https://pubmed.ncbi.nlm.nih.gov/32487715
https://pubmed.ncbi.nlm.nih.gov/32487715
Autor:
Zhiyu Huang, Yingqing Ran, Le An, Alberto Gobbi, Jonathan Maher, Claire Emson, Naomi S. Rajapaksa, Edna F. Choo, Yongsheng Chen, Steven Do, Aleksandr Kolesnikov, Ali A. Zarrin, Christine Yu, Marian C. Bryan, Joy Drobnick, Swathi Sujatha-Bhaskar, Hans Brightbill, James R. Kiefer, Jun Liang, Brent S. McKenzie, Ross Francis, John S. Wai, Patrick J. Lupardus, Kevin DeMent
Publikováno v:
ACS Med Chem Lett
[Image: see text] IRAK4 kinase activity transduces signaling from multiple IL-1Rs and TLRs to regulate cytokines and chemokines implicated in inflammatory diseases. As such, there is high interest in identifying selective IRAK4 inhibitors for the tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c741d6c5a8d5445e4411ce0bee8e8c5
https://europepmc.org/articles/PMC7073891/
https://europepmc.org/articles/PMC7073891/
Autor:
Sharmila Rajan, Eric Suto, Judy Young, Kevin Walsh, Wyne P. Lee, Yongmei Chen, Elaine Mai, Dinah Misner, Kate Senger, Dimitry M. Danilenko, Navneet Ratti, Ali A. Zarrin, Mary E. Keir, Patrícia de Almeida, Justin Lesch, Judy Mak, Kai H. Barck, Cary D. Austin, Cesar A. Corzo, Zhiyu Huang, Flavius Martin, Carrie Looney, Hirdesh Uppal, Hai Ngu, Yonglian Sun, Vineela D. Gandham, Wei-Ching Liang, Lauri Diehl, Surinder Jeet, Estelle Doudemont, Tori Lin, Jason DeVoss, Jeffrey Eastham, Wei Yu Lin, Azadeh Hadadianpour, Kathila R. Alatsis, Donnie Delarosa, Paula Katavolos, Juan Zhang, Katherine Bao, Richard A.D. Carano, Patrick Caplazi, Min Xu, Yan Wu, Robby M. Weimer, Mercedesz Balazs, Donghong Yan, Daqi Xu
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Colony-stimulating factor 1 (CSF1) and interleukin 34 (IL34) signal via the CSF1 receptor to regulate macrophage differentiation. Studies in IL34- or CSF1-deficient mice have revealed that IL34 function is limited to the central nervous system and sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fac9dee7283906729daedd8a3091d3c
https://doi.org/10.3389/fimmu.2019.02019
https://doi.org/10.3389/fimmu.2019.02019
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Microglia are specialized brain macrophages that play numerous roles in tissue homeostasis and response to injury. Colony stimulating factor 1 receptor (CSF1R) is a receptor tyrosine kinase required for the development, maintenance, and proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ab867877ee05907a1d4c23e5640431
https://pubmed.ncbi.nlm.nih.gov/31616414
https://pubmed.ncbi.nlm.nih.gov/31616414