Výsledky vyhledávání - "Alió Saenz, A"

Clinical Pharmacology and Safety of Trifarotene, a First‐in‐Class RARγ‐Selective Topical Retinoid

Autor: Khaled Benkali, Michael Graeber, Nathalie Wagner, Alessandra B Alió Saenz, Michel Poncet

Publikováno v: Journal of Clinical Pharmacology

Trifarotene is a new drug with retinoic acid receptor activity and selectivity for retinoic acid receptor‐γ. The reported studies aimed at assessing the clinical pharmacology and safety of trifarotene. The clinical pharmacology of topical trifarot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a386d3826f9b08b4cfb85ac592c0b84
http://europepmc.org/articles/PMC7187247

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Long‐term safety and efficacy of trifarotene 50 μg/g cream, a first‐in‐class RAR‐γ selective topical retinoid, in patients with moderate facial and truncal acne

Autor: Lajos Kemény, Fran E Cook-Bolden, Ulrike Blume-Peytavi, Michael Graeber, Phoebe Rich, Faiz Ahmad, Joseph F. Fowler, Zoe Diana Draelos, Lawrence F. Eichenfield, Alessandra B Alió Saenz, Thomas Dirschka, Emil Tanghetti

Publikováno v: Journal of the European Academy of Dermatology and Venereology

Author(s): Blume-Peytavi, U; Fowler, J; Kemeny, L; Draelos, Z; Cook-Bolden, F; Dirschka, T; Eichenfield, L; Graeber, M; Ahmad, F; Alio Saenz, A; Rich, P; Tanghetti, E | Abstract: BackgroundTreatment for both facial and truncal acne has not sufficient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1197a48788aba905ca964bf4d4bc369
http://europepmc.org/articles/PMC7004112

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Long-term safety and efficacy of trifarotene 50 μg/g cream, a first-in-class RAR-γ selective topical retinoid, in patients with moderate facial and truncal acne

Autor: Blume-Peytavi, U, Fowler, J, Kemény, L, Draelos, Z, Cook-Bolden, F, Dirschka, T, Eichenfield, L, Graeber, M, Ahmad, F, Alió Saenz, A, Rich, P, Tanghetti, E

Publikováno v: Journal of the European Academy of Dermatology and Venereology : JEADV, vol 34, iss 1

BackgroundTreatment for both facial and truncal acne has not sufficiently been studied.ObjectivesTo evaluate the long-term safety and efficacy of trifarotene in both facial and truncal acne.MethodsIn a multicentre, open-label, 52-week study, patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::fa65acf94f8ffc0ee7da684cad64a4a7
https://escholarship.org/uc/item/51p3x2df

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Randomized phase 3 evaluation of trifarotene 50 μg/g cream treatment of moderate facial and truncal acne

Autor: Charles Lynde, Faiz Ahmad, Diane Thiboutot, Jonathan S. Weiss, Georg Popp, James Q Del Rosso, Lawrence Charles Parish, Nestor Sanchez Colon, Alessandra Alió Saenz, Ulrike Blume-Peytavi, Jerry Tan, Jolanta Weglovska, Michael Graeber, Linda Stein Gold, Sandra Marchese Johnson, Dagmara Witkowska, Melinda Gooderham

Publikováno v: Journal of the American Academy of Dermatology. 80(6)

Background Acne vulgaris often affects the face, shoulders, chest, and back, but treatment of nonfacial acne has not been rigorously studied. Objectives Assess the safety and efficacy of trifarotene 50 μg/g cream, a novel topical retinoid, in modera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a99c5ce2bfe230513f8fed397285bf6
https://pubmed.ncbi.nlm.nih.gov/30802558

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Is benzoyl peroxide 3% topical gel effective and safe in the treatment of acne vulgaris in Japanese patients? A multicenter, randomized, double-blind, vehicle-controlled, parallel-group study

Autor: Masahiro Yamada, Hirofumi Hashimoto, Makoto Ono, Makoto Kawashima, Alessandra B Alió Saenz

Publikováno v: The Journal of Dermatology. 41:795-801

Benzoyl peroxide (BPO) as an anti-acne medication is not yet approved in Japan. This study evaluated the efficacy and safety of a once-daily topical application of BPO 3% gel versus an inert vehicle gel in Japanese acne patients. Three hundred and si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020feb27305c22f14ecd036fa00ae309
https://doi.org/10.1111/1346-8138.12580

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Systemic exposure to benzoic acid and hippuric acid following topical application of clindamycin 1%/benzoyl peroxide 3% fixed-dose combination gel in Japanese patients with acne vulgaris

Autor: Hiroko Ino, Setsuo Hasegawa, Naoki Takahashi, Alessandra B Alió Saenz, Hirofumi Hashimoto, Akira Wakamatsu, Norie Nakahara

Publikováno v: Clinical Pharmacology in Drug Development. 4:18-24

Clindamycin 1%/benzoyl peroxide 3% fixed-dose combination gel (CLDM/BPO3%) is a topical product for the treatment of acne vulgaris. In this study, plasma and urine concentrations of benzoic acid (BA) and hippuric acid (HA) were analyzed to estimate t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b232e7cca96e19fad9e448478f88474b
https://doi.org/10.1002/cpdd.125

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Bioavailability of Clindamycin From a New Clindamycin Phosphate 1.2%-Benzoyl Peroxide 3% Combination Gel

Autor: Terry M. Jones, Stacy Jasper, Alessandra B Alió Saenz

Publikováno v: Clinical Pharmacology in Drug Development. 2:33-47

A new topical fixed-dose combination product containing clindamycin (1%, formulated as 1.2% clindamycin phosphate, CLNP 1.2%) with low strength (3%) benzoyl peroxide (BPO) in a methylparaben-free gel vehicle (CLNP 1.2%-BPO 3%-MPF) has been developed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff545929a1970f979c05a22f67ff3a06
https://doi.org/10.1002/cpdd.7

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