Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alié Brunissen"'
Autor:
Sandrine Sagan, Gérard Chassaing, Odile Convert, Solange Lavielle, Hubert Josien, Alié Brunissen, Jean-Philippe Berlose
Publikováno v:
Biopolymers. 39:133-147
Conformationally and configurationally restricted rotameric probes of phenylalanine have been incorporated in the sequence of substance P (SP)-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2-for analyzing the binding pockets of Phe7 (S7) and Phe8 (S8
Autor:
Alié Brunissen, Gérard Chassaing, Solange Lavielle, Philippe Karoyan, Sandrine Sagan, Hubert Josien
Publikováno v:
Bioorganic & Medicinal Chemistry. 4:2167-2178
The action of rotameric probes introduced either in position 7 or 8 in the sequence of substance P (SP) was investigated, i.e. l-tetrahydroisoquinoleic acid (Tic), l-fluorenylglycine (Flg), l-diphenylalanine (Dip), the diastereoisomers of l-1-indanyl
Publikováno v:
Tetrahedron Letters. 37:6713-6716
(S)-αMethylmethionine, (S)-αMethylleucine, 2-aminoisobutyric acid and (S)-αMethylphenylalanine have been incorporated by solid phase peptide strategy in a peptide sequence. The coupling reactions of these Boc-αMe amino acids and of the following
Publikováno v:
European Journal of Biochemistry. 225:827-843
The S/T-X1-X2-N-P-X3-X4-Y highly conserved sequence of the seventh transmembrane (TM VII) segment of G-protein-coupled receptors is not present in the photon receptor bacteriorhodopsin TM VII domain. Despite this noticeable discrepancy in sequence, t
Autor:
Alié Brunissen, Gérard Chassaing, Solange Lavielle, Mimoun Ayoub, Hubert Josien, Albert Loffet
Publikováno v:
ChemInform. 30
Publikováno v:
European journal of biochemistry. 242(2)
The third helix of antennapedia homeodomain pAntp-(43-58) can translocate through cell membrane and has been used as an intracellular vehicle for delivering peptides and oligonucleotides. The conformational and associative behaviour of two peptidic v
Autor:
Sophie Calvet, Gérard Chassaing, Alain Prochiantz, Alain Trembleau, Alié Brunissen, Daniele Derossi
Publikováno v:
The Journal of biological chemistry. 271(30)
We have recently reported that a 16-amino acid long polypeptide corresponding to the third helix of the DNA binding domain (homeodomain) of Antennapedia, a Drosophila transcription factor, is internalized by cells in culture (Derossi, D., Joliot, A.
Autor:
Jean Claude Beaujouan, Hubert Josien, Jacques Glowinski, Solange Lavielle, Monique Saffroy, Alié Brunissen, Yvette Torrens, Gérard Chassaing
Publikováno v:
Journal of medicinal chemistry. 37(11)
Constrained analogues of phenylalanine have been conceptually designed for analyzing the binding pockets of Phe7 (S7) and Phe8 (S8), two aromatic residues important for the pharmacological properties of SP, i.e., L-tetrahydroisoquinoleic acid, L-diph
Autor:
Odile Convert, F. Petitet, Jacques Glowinski, Alié Brunissen, M. Saffroy, Gérard Chassaing, A. Carruette, M. Rodriguez, J. Martinez, Claude Garret, Solange Lavielle, Yvette Torrens, Jean-Claude Beaujouan
Publikováno v:
International journal of peptide and protein research. 42(3)
Previous studies with Substance P (SP) antagonists (GR 71251, [DPro9, Pro10, Trp11]SP and [DPro9, MeLeu10, Trp11]SP) have suggested the existence in the guinea-pig ileum (GPI) of two distinct tachykinin receptors associated with the contractile respo
Autor:
A. Carruette, F. Petitet, Jean-Claude Beaujouan, Solange Lavielle, Jacques Glowinski, Claude Garret, Gérard Chassaing, Alié Brunissen, Yvette Torrens, M. Saffroy
Publikováno v:
Neuropeptides. 23(2)
Structural considerations led us to postulate that the introduction of the dipeptides DPro 9 -Pro 10 and DPro 9 -MeLeu 10 should lock the C-terminal tetrapeptide of SP in a type II' β-turn structure, a prerequisite for antagonist activity. Indeed, a