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pro vyhledávání: '"Ali, Dodhy"'
Autor:
Ann L, White, H T Claude, Chan, Ruth R, French, Jane, Willoughby, C Ian, Mockridge, Ali, Roghanian, Christine A, Penfold, Steven G, Booth, Ali, Dodhy, Marta E, Polak, Elizabeth A, Potter, Michael R, Ardern-Jones, J Sjef, Verbeek, Peter W M, Johnson, Aymen, Al-Shamkhani, Mark S, Cragg, Stephen A, Beers, Martin J, Glennie
Publikováno v:
Cancer cell. 27(1)
Monoclonal antibody (mAb) drugs that stimulate antitumor immunity are transforming cancer treatment but require optimization for maximum clinical impact. Here, we show that, unlike other immunoglobulin isotypes, human IgG2 (h2) imparts FcγR-independ