Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alfredo Ruffo"'
Publikováno v:
Rendiconti Lincei. 13:37-43
We investigated on cultured 3T3-L1 pre-adipocytes incubated with and withoutα-hydroxy-β-oxalosuccinic acid, shortly named oxalomalate (OMA), the rate of growth and differentiation together with fatty acids and protein synthesis and the variation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d6b33cf00faf4c35ea4f41fd8e72127
https://doi.org/10.1007/bf02904669
https://doi.org/10.1007/bf02904669
Autor:
Guido Mele, Alfredo Colonna, Concetta Pietropaolo, Alfredo Ruffo, Gaetano Ricciardelli, Michela Festa
Publikováno v:
Journal of Biological Chemistry. 275:36708-36712
The role of iron-dependent oxidative metabolism in protecting the oxidable substrates contained in mature adipocytes is still unclear. Because differentiation increases ferritin formation in several cell types, thereby leading to an accumulation of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81aea8cf831b76a4be11d56bcf8e6dc4
https://doi.org/10.1074/jbc.m004988200
https://doi.org/10.1074/jbc.m004988200
Autor:
Michela Festa, Alfredo Ruffo
Publikováno v:
Rendiconti Lincei. 11:111-114
It has been investigated whether oxalomalate (OMA) the competitive inhibitor of cytosolic aconitase might extend its effect also on IRP-1, an iron regulatory protein, probably present in a commercial preparation of purified aconitase. The results sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abcad5237c28a9a276f200daae8a6244
https://doi.org/10.1007/bf02904377
https://doi.org/10.1007/bf02904377
Publikováno v:
Biochemical Journal. 348:315-320
We investigated the effect of oxalomalate (OMA, α-hydroxy-β-oxalosuccinic acid), a competitive inhibitor of aconitase, on the RNA-binding activity of the iron-regulatory proteins (IRP1 and IRP2) that control the post-transcriptional expression of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b340075faafe117b38b72f30292a3ef
https://doi.org/10.1042/bj3480315
https://doi.org/10.1042/bj3480315
Autor:
Alfredo Ruffo
Publikováno v:
Rendiconti Lincei. 10:25-62
Sono stati riportati in forma riassuntiva alcuni dei risultati molto validi che hanno rappresentato il pieno successo della ricerca biochimica tra gli anni 1930 e ’50. Sono gli anni della grande svolta innovativa apportata dalle applicazioni tecnol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630a49912e0c266a89897b7afe239571
https://doi.org/10.1007/bf02904451
https://doi.org/10.1007/bf02904451
Publikováno v:
Rendiconti Lincei. 10:21-24
It has been investigatedin vitro the effect of oxalomalate (OMA) on the ferritin mRNA binding capacity of the bifunctional protein aconitase/IRP-1 contained in lysates of confluent cultures of 3T3-L1 fibroblasts. After short time of incubation with O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7297c7c5d121ee15f905c101fe787807
https://doi.org/10.1007/bf02904450
https://doi.org/10.1007/bf02904450
Publikováno v:
Rendiconti Lincei. 8:117-121
Ferritin content and the specific RNA binding capacity of IRP1/aconitase were determined in lysates of 3T3-L1 adipocytes during their differentiation promoted by the addition to the culture of isobutyl-methylxantine, insulin and dexamethasone (DXM) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d90e9d65489d271eefde4391f2d56cbc
https://doi.org/10.1007/bf03002326
https://doi.org/10.1007/bf03002326
3T3-L1 cells can be induced to differentiate by exposing cell culture to a medium containing 3-isobutyl-l-methyl-xanthine together with insulin and dexamethasone. We have previously observed that oxalomalate which inhibits aconitase thus blocking the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3070e89d7f39a476f04ab56fdc49f0f
http://hdl.handle.net/11588/352199
http://hdl.handle.net/11588/352199
