Development and selective grain make plasticity 'take the lead' in adaptive evolution

Autor: Miguel Brun-Usan, Alfredo Rago, Christoph Thies, Tobias Uller, Richard A. Watson

Publikováno v: BMC Ecology and Evolution, Vol 21, Iss 1, Pp 1-17 (2021)

Abstract Background Biological evolution exhibits an extraordinary capability to adapt organisms to their environments. The explanation for this often takes for granted that random genetic variation produces at least some beneficial phenotypic variat

Externí odkaz: https://doaj.org/article/81d307e08c604733884e5a13f3b41cba

Sex biased expression and co-expression networks in development, using the hymenopteran Nasonia vitripennis.

Autor: Alfredo Rago, John H Werren, John K Colbourne

Publikováno v: PLoS Genetics, Vol 16, Iss 1, p e1008518 (2020)

Sexual dimorphism requires regulation of gene expression in developing organisms. These developmental differences are caused by differential expression of genes and isoforms. The effect of expressing a gene is also influenced by which other genes are

Externí odkaz: https://doaj.org/article/2b0182ce897a4d91bf07256e58027422

Function and evolution of DNA methylation in Nasonia vitripennis.

Autor: Xu Wang, David Wheeler, Amanda Avery, Alfredo Rago, Jeong-Hyeon Choi, John K Colbourne, Andrew G Clark, John H Werren

Publikováno v: PLoS Genetics, Vol 9, Iss 10, p e1003872 (2013)

The parasitoid wasp Nasonia vitripennis is an emerging genetic model for functional analysis of DNA methylation. Here, we characterize genome-wide methylation at a base-pair resolution, and compare these results to gene expression across five develop

Externí odkaz: https://doaj.org/article/6d1f9f495f384f7292c282fedc5a8d00

Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial

Autor: Jakob Hendel, Maria Juul Nielsen, Alfredo Rago, Jesper A.B. Strickertsson, Albin Sandelin, Lars H. Engelholm, Kristoffer Vitting-Seerup, Christa Broholm, Christina V Müller, Adam Baker, Cathrine Melsæther, Kim B. Jensen, Stine Sloth, Yun Chen, Jette Bornholdt

Publikováno v: Gut Microbes, Vol 12, Iss 1 (2020)
Bornholdt, J, Chen, Y, Rago, A, Sloth, S, Hendel, J, Melsæther, C, Müller, C V, Juul Nielsen, M, Strickertsson, J, Engelholm, L, Vitting-Seerup, K, Jensen, K B, Baker, A & Sandelin, A 2020, ' Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects : a randomized trial ', Gut Microbes, vol. 12, no. 1, pp. 1-14 . https://doi.org/10.1080/19490976.2020.1854639
Gut Microbes
article-version (VoR) Version of Record

The specific effects of administering live probiotics in the human gut are not well characterized. To this end, we investigated the immediate effect of Lactobacillus rhamnosus GG (LGG) in the jejunum of 27 healthy volunteers 2 h after ingestion using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7913ba5aa77dbfd6a07f7f993259b1ba
https://doaj.org/article/9243eb2759cc40ca901701ba70e54b10

Developmental plasticity and evolutionary explanations

Autor: Illiam S. C. Jackson, Alfredo Rago, Nathalie Feiner, Reinder Radersma, Tobias Uller

Publikováno v: Evolution and Development, 22(1-2), 47-55
Evolution and Development 22 (2020) 1-2

Developmental plasticity looks like a promising bridge between ecological and developmental perspectives on evolution. Yet, there is no consensus on whether plasticity is part of the explanation for adaptive evolution or an optional "add-on" to genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48499359157c9688620f911c91037e28
https://research.wur.nl/en/publications/developmental-plasticity-and-evolutionary-explanations