Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alfredo Piñeyro López"'
Autor:
Marco A. Flores-Diego, Salvador Borrego-Alvarado, María E. Gamino-Peña, Alfredo Piñeyro-López, Magdalena Gómez-Silva, Rigoberto Vargas-Zapata, Everardo Piñeyro-Garza, Raúl Reyes-Araiza, Martha E. Salazar-Leal
Publikováno v:
Clinical Therapeutics. 31:411-417
The proprietary form of topiramate is indicated in Mexico as an antiepileptic agent and in the prophylaxis of migraine headaches. However, before generic topiramate is placed on the market, pharmacokinetic studies investigating the bioequivalence of
Autor:
Salvador Namur, Rubén Luján Rangel, Noemí Wacksman, Everardo Piñeyro-Garza, Raúl Reyes-Araiza, Alfredo Piñeyro-López, Alberto de Lago, Magdalena Gómez Silva, Mario González-de la Parra, Oscar Torres-Alanís
Publikováno v:
Clinical Therapeutics. 27:1607-1611
Azithromycin is related to erythromycin but is more active against gram-negative bacteria and less active against streptococci and staphylococci compared with erythromycin. For these reasons, and because of convenience of dosing (QD for 3 days), azit
Autor:
Ma de la Luz Salazar Cavazos, Alfredo Piñeyro López, Víctor Manuel Torres de la Cruz, Noemí Waksman de Torres
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 28:693-704
A rapid, precise, and sensitive method has been developed for the simultaneous determination of five antiepileptic drugs (carbamazepine, phenobarbital, diphenylhydantoin, primidone, and oxcarbazepine) and six metabolites (from carbamazepine, carbamaz
Publikováno v:
Toxicology in Vitro. 19:47-53
T-514 (Peroxisomicine A(1)) from Karwinskia humboldtiana is a dimeric hydroxyanthracenone with a highly selective cytotoxic effect on tumor cells. We evaluated the metabolism of this compound in two in vitro systems (liver microsomes and hepatocytes)
Publikováno v:
Journal of Chromatography B. 783:85-92
Peroxisomicine A1 is a potential antineoplastic substance extracted from plants of the genus Karwinskia. An RP-HPLC–DAD method was developed and validated for the separation and quantification of four isomers of this compound. These isomers coelute
Publikováno v:
Human & Experimental Toxicology. 21:573-577
The efficacy of meso-2,3-dimercaptosuccinic acid (DMSA) was evaluated in workers occupationally exposed to lead (Pb; blood level >50 mg //dL). Ten men were given 600 mg of DMSA per orem daily, for five days. Pb concentrations of whole blood and urine
Autor:
Alfredo Piñeyro López, Ma. de la Luz Salazar, Noemí Waksman de Torres, Pedro Luis López de Alba
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 25:1747-1760
A simple and reliable method for determination of isoperoximicine in peroxisomicine-contaminated batches was developed. The method consists of mathematical derivatization of zero order chromatograms, plus a standard addition technique required to inc
Autor:
Alfredo Piñeyro-López, N. Waksman de Torres, A. Garcia-Luna, Rosalba Ramírez-Durón, Lourdes Garza-Ocañas
Publikováno v:
Pharmaceutical Biology. 40:440-447
Peroxisomicine A1 (PA1) is a dimeric anthracenone obtained from plants of the genus Karwinskia. Toxicological studies have demonstrated a selective toxicity of peroxisomicine A1 on various human tumor cell lines in vitro. For this reason it has been
Autor:
Karl B. Rechinger, Jan A.K.W. Kiel, Vladimira Torres-González, Rigoberto Vargas-Zapata, Julio Sepúlveda-Saavedra, Ineke Keizer-Gunnink, Alfredo Piñeyro-López, Marten Veenhuis
Publikováno v:
Toxicon, 37(2), 385-398
Previously we demonstrated that peroxisomicine A1 (T-514), a plant toxin isolated from Karwinskia species, has a deteriorating effect on the integrity of peroxisomes of methylotrophic yeasts. Here we describe two strains of Hansenula polymorpha, affe
Autor:
Myrthala Moreno-Sepúlveda, Julio Sepúlveda-Saavedra, Raquel Guadalupe Ballesteros-Elizondo, Alfredo Piñeyro-López, Rigoberto Vargas-Zapata
Publikováno v:
Toxicon. 35:777-783
Peroxisomicine is a toxic compound isolated from plants of the genus Karwinskia (Rhamnaceae). This toxin produces irreversible and selective damage to the peroxisomes of yeast cells in vivo. Peroxisomicine also inhibits catalase activity in vitro, wh