Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Alfredo Perales Puchalt"'
Autor:
Hyeree Choi, Michelle Ho, Opeyemi S. Adeniji, Leila Giron, Devivasha Bordoloi, Abhijeet J. Kulkarni, Alfredo Perales Puchalt, Mohamed Abdel-Mohsen, Kar Muthumani
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Sialic acid-binding Immunoglobulin-like lectin-9 (Siglec-9) is a glyco-immune negative checkpoint expressed on several immune cells. Siglec-9 exerts its inhibitory effects by binding to sialoglycan ligands expressed on cancer cells, enabling them to
Externí odkaz:
https://doaj.org/article/c25bf30ad0a244629991b3e95285bea3
Autor:
Daniel H. Park, Kevin Liaw, Pratik Bhojnagarwala, Xizhou Zhu, Jihae Choi, Ali R. Ali, Devivasha Bordoloi, Ebony N. Gary, Ryan P. O’Connell, Abhijeet Kulkarni, Diana Guimet, Trevor Smith, Alfredo Perales-Puchalt, Ami Patel, David B. Weiner
Publikováno v:
Molecular Therapy: Oncolytics, Vol 28, Iss , Pp 249-263 (2023)
Glioblastoma multiforme (GBM) is among the most difficult cancers to treat with a 5-year survival rate less than 5%. An immunotherapeutic vaccine approach targeting GBM-specific antigen, EGFRvIII, previously demonstrated important clinical impact. Ho
Externí odkaz:
https://doaj.org/article/711f820743e943359c7145d81fe55987
Autor:
Manisha Bhutani, Alfred Garfall, Katarina Uttervall, Saad Z Usmani, Lionel Karlin, Lotfi Benboubker, Hareth Nahi, Jesús San Miguel, Danielle Trancucci, Keqin Qi, Tara Stephenson, Alfredo Perales-Puchalt, Katherine Chastain, Ajai Chari
Publikováno v:
HemaSphere, Vol 7, p e90600b0 (2023)
Externí odkaz:
https://doaj.org/article/57fb171e99b34443b7272faba575de36
Autor:
Niels W.C.J. van de Donk, Alfred Garfall, Lotfi Benboubker, Katarina Uttervall, Kaz Groen, Laura Rosiñol Dachs, Caroline Hodin, Tara Stephenson, Danielle Trancucci, Alfredo Perales-Puchalt, Rachel Kobos, Arnob Banerjee, Maria-Victoria Mateos
Publikováno v:
HemaSphere, Vol 7, p e43149cb (2023)
Externí odkaz:
https://doaj.org/article/5d865868588442d498401f6a9a903b40
Autor:
Kristine Frerichs, Christie Verkleij, Maria-Victoria Mateos, Sonja Zweegman, Kaz Groen, Ilse Kuipers, Tom Martin, Cesar Rodriguez, Ajay Nooka, Sandy Kruijswijk, Sheri Skerget, Margaret Doyle, Arnob Banerjee, Katherine Chastain, Alfredo Perales-Puchalt, Tara Stephenson, Clarissa Uhlar, Rachel Kobos, Raluca Verona, Niels W.C.J. van de Donk
Publikováno v:
HemaSphere, Vol 7, p e5193345 (2023)
Externí odkaz:
https://doaj.org/article/93101672d5c242309f05ac55ecdf6a47
Autor:
Devivasha Bordoloi, Pratik S. Bhojnagarwala, Alfredo Perales-Puchalt, Abhijeet J. Kulkarni, Xizhou Zhu, Kevin Liaw, Ryan P. O’Connell, Daniel H. Park, Daniel W. Kulp, Rugang Zhang, David B. Weiner
Publikováno v:
JCI Insight, Vol 7, Iss 22 (2022)
Despite advances in ovarian cancer (OC) therapy, recurrent OC remains a poor-prognosis disease. Because of the close interaction between OC cells and the tumor microenvironment (TME), it is important to develop strategies that target tumor cells and
Externí odkaz:
https://doaj.org/article/a607704c926640839bde5206f6333f01
Autor:
Urvi S. Zankharia, Sagar Kudchodkar, Makan Khoshnejad, Alfredo Perales-Puchalt, Hyeree Choi, Michelle Ho, Faraz Zaidi, Kenneth E. Ugen, Joseph J. Kim, David B. Weiner, Kar Muthumani
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 9, Pp 2156-2164 (2020)
Hepatitis B virus (HBV) causes a potentially life-threatening liver infection that frequently results in life-long chronic infection. HBV is responsible for 887,000 deaths each year, most resulting from chronic liver diseases and hepatocellular carci
Externí odkaz:
https://doaj.org/article/15e32ce0be1f43fb91d185f483eef008
Autor:
Makan Khoshnejad, Alfredo Perales-Puchalt, Yaya Dia, Peng Xiao, Ami Patel, Ziyang Xu, Xizhou Zhu, Kun Yun, Ishana Baboo, Rehman Qureshi, Laurent Humeau, Kar Muthumani, David B. Weiner
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 652-663 (2020)
Arginase is a complex and unique enzyme that plays diverse roles in health and disease. By metabolizing arginine, it can shape the outcome of innate and adaptive immune responses. The immunomodulatory capabilities of arginase could potentially be app
Externí odkaz:
https://doaj.org/article/4b6264ac10cc4e5597009cccad27ac16
Autor:
Ziyang Xu, Megan C. Wise, Neethu Chokkalingam, Susanne Walker, Edgar Tello‐Ruiz, Sarah T. C. Elliott, Alfredo Perales‐Puchalt, Peng Xiao, Xizhou Zhu, Ruth A. Pumroy, Paul D. Fisher, Katherine Schultheis, Eric Schade, Sergey Menis, Stacy Guzman, Hanne Andersen, Kate E. Broderick, Laurent M. Humeau, Kar Muthumani, Vera Moiseenkova‐Bell, William R. Schief, David B. Weiner, Daniel W. Kulp
Publikováno v:
Advanced Science, Vol 7, Iss 8, Pp n/a-n/a (2020)
Abstract Nanotechnologies are considered to be of growing importance to the vaccine field. Through decoration of immunogens on multivalent nanoparticles, designed nanovaccines can elicit improved humoral immunity. However, significant practical and m
Externí odkaz:
https://doaj.org/article/a5cfd50706de4598866740c702c06b33
Autor:
Ziyang Xu, Megan C. Wise, Hyeree Choi, Alfredo Perales-Puchalt, Ami Patel, Edgar Tello-Ruiz, Jacqueline D. Chu, Kar Muthumani, David B. Weiner
Publikováno v:
EBioMedicine, Vol 35, Iss , Pp 97-105 (2018)
Background: Despite vigorous and ongoing efforts, active immunizations have yet to induce broadly neutralizing antibodies (bNAbs) against HIV-1. An alternative approach is to achieve prophylaxis with long-term expression of potent biologic HIV-1 inhi
Externí odkaz:
https://doaj.org/article/5260fc14d59a4d9cb8e5ebe8ff2bb3f9