Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Alfredo Ortega-Alonso"'
Autor:
Joonatan Palmu, Christin S. Börschel, Alfredo Ortega-Alonso, Lajos Markó, Michael Inouye, Pekka Jousilahti, Rodolfo A. Salido, Karenina Sanders, Caitriona Brennan, Gregory C. Humphrey, Jon G. Sanders, Friederike Gutmann, Dominik Linz, Veikko Salomaa, Aki S. Havulinna, Sofia K. Forslund, Rob Knight, Leo Lahti, Teemu Niiranen, Renate B. Schnabel
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104583- (2023)
Summary: Background: Atrial fibrillation (AF) is an important heart rhythm disorder in aging populations. The gut microbiome composition has been previously related to cardiovascular disease risk factors. Whether the gut microbial profile is also ass
Externí odkaz:
https://doaj.org/article/4d04f3726b78491dac33d3efd203cd5c
Autor:
Aaron Kortteenniemi, Alfredo Ortega-Alonso, Amir-Homayoun Javadi, Owen Thomas, Tommi Tolmunen, Tuukka Kotilainen, Jan Wikgren, Soili M. Lehto
Publikováno v:
Psychiatria Fennica, Vol 51, Pp 142-161 (2020)
Transcranial electrical stimulation (tES) has shown promise in the treatment of conditions such as depression and chronic pain with mild-to-moderate adverse effects (AEs). Few previous studies have attempted to identify factors predicting tES-induce
Externí odkaz:
https://doaj.org/article/c943e4f80dd848dca215c16791ddffc0
Autor:
Aaron Kortteenniemi, Alfredo Ortega-Alonso, Amir-Homayoun Javadi, Tommi Tolmunen, Toni Ali-Sisto, Tuukka Kotilainen, Jan Wikgren, Leila Karhunen, Vidya Velagapudi, Soili M. Lehto
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
BackgroundTranscranial direct current stimulation (tDCS), a putative treatment for depression, has been proposed to affect peripheral metabolism. Metabolic products from brain tissue may also cross the blood–brain barrier, reflecting the conditions
Externí odkaz:
https://doaj.org/article/5566ffdc857f496d9e152e3078dfa606
Autor:
Nicholas J. Bradshaw, Liisa Ukkola-Vuoti, Maiju Pankakoski, Amanda B. Zheutlin, Alfredo Ortega-Alonso, Minna Torniainen-Holm, Vishal Sinha, Sebastian Therman, Tiina Paunio, Jaana Suvisaari, Jouko Lönnqvist, Tyrone D. Cannon, Jari Haukka, William Hennah
Publikováno v:
Open Biology, Vol 7, Iss 11 (2017)
Genetic studies of familial schizophrenia in Finland have observed significant associations with a group of biologically related genes, DISC1, NDE1, NDEL1, PDE4B and PDE4D, the ‘DISC1 network’. Here, we use gene expression and psychoactive medica
Externí odkaz:
https://doaj.org/article/4b629c90c56d4cd896a19d72e6ebdeb4
Autor:
Marius R. Robciuc, Jussi Naukkarinen, Alfredo Ortega-Alonso, Henna Tyynismaa, Taneli Raivio, Aila Rissanen, Jaakko Kaprio, Christian Ehnholm, Matti Jauhiainen, Kirsi H. Pietiläinen
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 8, Pp 1575-1582 (2011)
Animal studies have suggested that angiopoietin-like 4 (Angptl4) regulates adiposity through central and peripheral mechanisms. The aim of this study was to investigate whether serum concentration and adipose tissue expression of Angptl4 are associat
Externí odkaz:
https://doaj.org/article/5a0474069e9a4871b51c3961040d73ad
Autor:
Andrea Ganna, Alfredo Ortega-Alonso, Aki Havulinna, Veikko Salomaa, Jaakko Kaprio, Nancy L Pedersen, Patrick F Sullivan, Erik Ingelsson, Christina M Hultman, Patrik K E Magnusson
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83101 (2013)
Twin registries around the globe have collected DNA samples from large numbers of monozygotic and dizygotic twins. The twin sample collections are frequently used as controls in disease-specific studies together with non-twins. This approach is unbia
Externí odkaz:
https://doaj.org/article/0a06cd2350ac43e7949bb497599f860e
Autor:
Vishal Sinha, Jaana Suvisaari, Pekka Jylhä, Erkki Isometsä, Tyrone D. Cannon, Minna Torniainen-Holm, William Hennah, Alfredo Ortega-Alonso, Liisa Ukkola-Vuoti, Iiris Hovatta, Jaakko Kaprio, Annamari Tuulio-Henriksson, Tiina Paunio, Sebastian Therman, Jouko Lönnqvist
Publikováno v:
Molecular Psychiatry. 26:816-824
We have previously reported a replicable association between variants at the PDE4D gene and familial schizophrenia in a Finnish cohort. In order to identify the potential functional mutations underlying these previous findings, we sequenced 1.5 Mb of
Autor:
Alfredo Ortega-Alonso, Tyrone D. Cannon, Sebastian Therman, Tiina Paunio, Annamari Tuulio-Henriksson, Erkki Isometsä, Outi Linnaranta, Jaana Suvisaari, Liisa Ukkola-Vuoti, Jaakko Kaprio, William Hennah, Minna Torniainen-Holm, Jouko Lönnqvist, Vishal Sinha, Pekka Jylhä, Amanda B Zheutlin, Iiris Hovatta
Publikováno v:
Schizophrenia Bulletin Open. 1
Through copy number variations, the 16p13.11 locus has been consistently linked to mental disorders. This locus contains the NDE1 gene, which also encodes microRNA-484. Both of them have been highlighted to play a role in the etiology of mental illne
Autor:
Jesper Lundbom, Antti J. Kangas, Joel T. Rämö, Pasi Soininen, Nina Lundbom, Aila Rissanen, Kirsi H. Pietiläinen, Antti Hakkarainen, Mika Ala-Korpela, Sanna Kaye, Leonie H. Bogl, Alfredo Ortega-Alonso, Jaakko Kaprio
Publikováno v:
Metabolism. 65:111-121
Objective. To investigate how obesity, insulin resistance and low-grade inflammation link to circulating metabolites, and whether the connections are due to genetic or environmental factors. Subjects and methods. Circulating serum metabolites were de
Variants in regulatory elements ofPDE4Dassociate with Major Mental Illness in the Finnish population
Autor:
Erkki Isometsä, Jaakko Kaprio, Minna Torniainen-Holm, William Hennah, Alfredo Ortega-Alonso, Liisa-Ukkola Vuoti, Jouko Lönnqvist, Sebastian Therman, Vishal Sinha, Pekka Jylhä, Tyrone D. Cannon, Jaana Suvisaari, Iiris Hovatta, Annamari Tuulio-Henriksson, Tiina Paunio
We have previously reported a replicable association between variants at thePDE4Dgene and familial schizophrenia in a Finnish cohort. In order to identify the potential functional mutations alluded to by these previous findings, we sequenced the 1.5M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a143841fa5dbb5f0e0ee8c92219287d
https://doi.org/10.1101/390518
https://doi.org/10.1101/390518