Výsledky vyhledávání - "Alfredo J. Zamora"

Impact ofgspOncogene on the Expression of Genes Coding for Gsα, Pit-1, Gi2α, and Somatostatin Receptor 2 in Human Somatotroph Adenomas: Involvement in Octreotide Sensitivity1

Autor: P. Jaquet, Alain Enjalbert, Alfredo J. Zamora, Ginette Gunz, I. Pellegrini-Bouiller, Anne Barlier

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 84:2759-2765

The impact of the gsp oncogene on the expression of genes engaged in the somatotroph cell phenotype remains poorly understood in human somatotroph adenomas. As the gsp oncogene is associated with an increased octreotide (somatostatin agonist) sensiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be46f1c89ee4b2d1d1501a11dcd5dad0
https://doi.org/10.1210/jcem.84.8.5919

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Expression of the Members of the Ptx Family of Transcription Factors in Human Pituitary Adenomas1

Autor: Alain Enjalbert, I. Pellegrini-Bouiller, Michel Grino, Alfredo J. Zamora, Ginette Gunz, François Grisoli, Christine Manrique, Dominique Figarella-Branger, P. Jaquet

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 84:2212-2220

A number of putative transcription factors described in the pituitary have been implicated as key elements in the processes that direct pituitary development. Three recently described proteins, Ptx1, Ptx2, and Ptx3, define a new family of transcripti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fb9e24b9588394cf5670c3793c59a80
https://doi.org/10.1210/jcem.84.6.5760

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Ursodeoxycholate protects against ethanol-induced liver mitochondrial injury

Autor: J.C. Montet, Laurent Tabouy, Alfredo J Zamora, A.M. Montet, L. Oliva, Françoise Beaugé

Publikováno v: Life Sciences. 63:2259-2270

The purpose of this work was to examine whether ursodeoxycholate (UDC), a hydrophilic bile salt, could reduce mitochondrial liver injury from chronic ethanol consumption in rats. Animals were pair-fed liquid diets containing 36% of calories as ethano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30f4b3e056fce6cb2b4d396ed8c3880
https://doi.org/10.1016/s0024-3205(98)00511-6

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An In Situ Hybridization Histochemistry Technique Allowing Simultaneous Visualization by the Use of Confocal Microscopy of Three Cellular mRNA Species in Individual Neurons

Autor: Alfredo J. Zamora, Michel Grino

Publikováno v: Journal of Histochemistry & Cytochemistry. 46:753-759

We present a specific and sensitive method for simultaneous detection of three mRNA species in individual neurons. The method relies on the use of riboprobes labeled with [35S]-UTP, digoxigenin-UTP, or biotin-UTP. The nonradioactive probes were seque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22a67d42de0af9d995c865086d36ff6
https://doi.org/10.1177/002215549804600608

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Pronostic and Therapeutic Consequences of Gsα Mutations in Somatotroph Adenomas1

Autor: Anne Barlier, Isabelle Morange-Ramos, P. Jaquet, Alfredo J. Zamora, Ginette Gunz, Dominique Figarella-Branger, H. Dufour, Alain Enjalbert

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 83:1604-1610

Human pituitary somatotroph adenomas can be associated with mutations of the s alpha-subunit of G proteins. However, the impact of the gsp mutations on the tumoral phenotype is not well understood at present. This study aims to determine whether the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b65239f24cd7e1d6686ef4c2068e1413
https://doi.org/10.1210/jcem.83.5.4797

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Expression of Angiotensin II Receptor Subtypes AT1A and AT1B in Enriched Fractions of Dispersed Rat Pituitary Cells

Autor: R. Rasolojanahary, C. Moreau, Claude Kordon, Catherine Llorens-Cortes, Alain Enjalbert, Alfredo J. Zamora

Publikováno v: Neuroendocrinology. 66:416-425

Differential evaluation of angiotensin II (Ang II) receptors (AT 1A, AT 1B and AT2) expression was performed in dispersed adenohypophyseal cells fractionated by unit gravity sedimentation. Binding of [125I-Sar1-Ile8]-Ang II and its displacement by sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3c57b41080af766d2faa63077c85334
https://doi.org/10.1159/000127267

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Lentiviral vectors efficiently transduce human gonadotroph and somatotroph adenomas in vitro. Targeted expression of transgene by pituitary hormone promoters

Autor: Catherine Roche, David Taïeb, Claude Bagnis, Alfredo J. Zamora, Anne Barlier, Ramahefarizo Rasolonjanahary, H. Dufour, Esteban Lavaque, Alain Enjalbert

Publikováno v: The Journal of endocrinology. 183(1)

Despite important advances in human therapeutics, no specific treatment for both non-functioning gonadotroph and resistant somatotroph adenomas is available. Gene transfer by viral vectors can be considered as a promising way to achieve a specific an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90eb42a9ea3318895819750c0d88262c
https://pubmed.ncbi.nlm.nih.gov/15525589

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Human Somatostatin Receptor Subtypes in Acromegaly: Distinct Patterns of Messenger Ribonucleic Acid Expression and Hormone Suppression Identify Different Tumoral Phenotypes 1

Autor: Michael D. Culler, Alfredo J. Zamora, Michel Grino, Frédéric Fina, Alexandru Saveanu, L'Houcine Ouafik, J. P. Moreau, P. Jaquet, Ginette Gunz, Alain Enjalbert

Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 2000, 85 (2), pp.781-792. ⟨10.1210/jcem.85.2.6338⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2000, 85 (2), pp.781-792. ⟨10.1210/jcem.85.2.6338⟩

Recently, studies using somatostatin (SRIF) analogs preferential for either the SRIF receptor 2 (SSTR2) or the SSTR5 subtype demonstrated a variable suppression of GH and PRL release from GH-secreting human adenomas. These data suggested the concept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453884fb3b21d882d02cbf572d3aae81
https://hal-amu.archives-ouvertes.fr/hal-01820857

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Anergy induction in encephalitogenic T cells by brain microvessel endothelial cells is inhibited by interleukin-1

Autor: Dominique Bernard, Sandrine Bourdoulous, Christine Le Page, Alfredo J. Zamora, Pierre-Olivier Couraud, Evelyne Beraud, Arnaud Ferry, A. Donny Strosberg

Publikováno v: European journal of immunology. 25(5)

Experimental autoimmune encephalomyelitis (EAE) is an inflammatory disease of the central nervous system (CNS) which can be induced, in susceptible strains like Lewis rats, by transfer of activated myelin basic protein (MBP)-specific CD4+ T lymphocyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88ccb9fa8bfea521f44083d79ff97ed
https://pubmed.ncbi.nlm.nih.gov/7539749

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