Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alfredo I. Sagredo"'
Autor:
Estefanie Dufey, José Manuel Bravo-San Pedro, Cristian Eggers, Matías González-Quiroz, Hery Urra, Alfredo I. Sagredo, Denisse Sepulveda, Philippe Pihán, Amado Carreras-Sureda, Younis Hazari, Eduardo A. Sagredo, Daniela Gutierrez, Cristian Valls, Alexandra Papaioannou, Diego Acosta-Alvear, Gisela Campos, Pedro M. Domingos, Rémy Pedeux, Eric Chevet, Alejandra Alvarez, Patricio Godoy, Peter Walter, Alvaro Glavic, Guido Kroemer, Claudio Hetz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
IRE1α plays a key role in the unfolded protein response (UPR) by promoting the unconventional splicing of the XBP1 and the selective cleavage of RNAs. Here the authors report that IRE1α is activated upon the DNA damage response and selectively cont
Externí odkaz:
https://doaj.org/article/41bd77e35d0d4d3fba7541fc5ffc6412
Autor:
Eduardo A. Sagredo, Alejandro Blanco, Alfredo I. Sagredo, Paola Pérez, Gonzalo Sepúlveda-Hermosilla, Fernanda Morales, Bettina Müller, Ricardo Verdugo, Katherine Marcelain, Olivier Harismendy, Ricardo Armisén
Publikováno v:
Biological Research, Vol 51, Iss 1, Pp 1-10 (2018)
Abstract Background Whole transcriptome RNA variant analyses have shown that adenosine deaminases acting on RNA (ADAR) enzymes modify a large proportion of cellular RNAs, contributing to transcriptome diversity and cancer evolution. Despite the advan
Externí odkaz:
https://doaj.org/article/a5c38d40f9104f5db1a081e849477aff
Autor:
Alfredo I. Sagredo, Eduardo A. Sagredo, Claudio Cappelli, Pablo Báez, Rodrigo E. Andaur, Constanza Blanco, Julio C. Tapia, César Echeverría, Oscar Cerda, Andrés Stutzin, Felipe Simon, Katherine Marcelain, Ricardo Armisén
Publikováno v:
Molecular Oncology, Vol 12, Iss 2, Pp 151-165 (2018)
Increased expression of the TRPM4 channel has been reported to be associated with the progression of prostate cancer. However, the molecular mechanism underlying its effect remains unknown. This work found that decreasing TRPM4 levels leads to the re
Externí odkaz:
https://doaj.org/article/39b1d5fb4e064e63b1ddea25c367a8f3
Publikováno v:
Translational Cancer Research. 6:S1371-S1383