Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Alfredo Giner-Sorolla"'
Autor:
Ronald G. Coffey, Alfredo Giner-Sorolla, Marina Sosa, John W. Hadden, Yulai Wang, Elba M. Hadden
Publikováno v:
International Journal of Immunopharmacology. 17:763-770
Methyl inosine monophosphate (MIMP) augments preferentially the in vitro responses of human and murine lymphocytes to a T-cell mitogen such as phytohemagglutinin (PHA) and inconsistently to a B-cell mitogen such as pokeweed or lipopolysaccharide (LPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264baf53c127afa0f52774513f16cab4
https://doi.org/10.1016/0192-0561(95)00065-a
https://doi.org/10.1016/0192-0561(95)00065-a
Publikováno v:
Annals of the New York Academy of Sciences. 685:458-463
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e59f5d08294d7bccb3cad00aa4c9a0
https://doi.org/10.1111/j.1749-6632.1993.tb35906.x
https://doi.org/10.1111/j.1749-6632.1993.tb35906.x
Autor:
Anutosh R. Saha, John W. Hadden, Elba M. Hadden, Marina Sosa, Yulai Wang, Alfredo Giner-Sorolla, Jorge Coto
Publikováno v:
International Journal of Immunopharmacology. 14:1259-1266
Inosine 5′ - methyl monophosphate (MIMP) is a new immunomodulator designed to improve upon the activity of other thymomimetic purines. In Balb/c mice, MIMP was assessed for toxicity and activity on immune responses. The lethal dose for half the mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d3e87323bc73c27799cca4169216ca
https://doi.org/10.1016/0192-0561(92)90062-p
https://doi.org/10.1016/0192-0561(92)90062-p
Autor:
Robert M. Nelson, Alfredo Giner-Sorolla, Elba M. Hadden, Craig Monell, Steven Specter, John W. Hadden, Joseph Ongradi, Mette Strand, Marina Sosa
Publikováno v:
International Journal of Immunopharmacology. 14:555-563
MIMP is a new thymomimetic purine under development for immunorestorative therapy. Lymphocytes were obtained from eight patients with acquired immunodeficiency disease (AIDS), eight with symptomatic pre-AIDS (ARC), and 22 normal controls and were sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d36f449636b94564f125f8f8e50e48af
https://doi.org/10.1016/0192-0561(92)90116-3
https://doi.org/10.1016/0192-0561(92)90116-3
Publikováno v:
International Journal of Immunopharmacology. 13:49-54
Prior work has documented the thymomimetic and immunotherapeutic activity of purine molecules related in structure to inosine. Synthesis of a series of new structures has yielded a stable methylated form of IMP resistant to hydrolysis by 5′ nucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02f7f77c3458e8266169f6ac2609ac9
https://doi.org/10.1016/0192-0561(91)90124-p
https://doi.org/10.1016/0192-0561(91)90124-p
Publikováno v:
Ciba Foundation Symposium-Chemistry and Biology of Purines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99a6f190953477eb2588347b53ec8f84
https://doi.org/10.1002/9780470719015.ch2
https://doi.org/10.1002/9780470719015.ch2
Autor:
Ronald G. Coffey, Elba M. Hadden, Marina Sosa, Alfredo Giner-Sorolla, John W. Hadden, Yulai Wang
Publikováno v:
International Journal of Immunopharmacology. 13:761
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5da1d8ac4821f3a0856b3b60618f5f3d
https://doi.org/10.1016/0192-0561(91)90288-i
https://doi.org/10.1016/0192-0561(91)90288-i
Autor:
Robert Settineri, Thomas Spira, Alfredo Giner-Sorolla, Elba M. Hadden, Lionel N. Simon, John W. Hadden
Publikováno v:
International Journal of Immunopharmacology. 4:235-242
NPT 15392 (Erythro-9 (2-hydroxy-3 nonyl) hypoxanthine), a novel heterocyclic immunomodulatory compound, was analyzed over a broad concentration range on a variety of human blood leukocyte functions in vitro. NPT 15392 augmented mitogen-induced lympho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cca8eb5661300d3a3cbe5399d7375f6
https://doi.org/10.1016/0192-0561(82)90053-4
https://doi.org/10.1016/0192-0561(82)90053-4
Autor:
Lucy M. Anderson, Jerry M. Rice, C. W. Riggs, S. Rehm, Robert M. Kovatch, Akihiro Hagiwara, Alfredo Giner-Sorolla
Publikováno v:
Cancer Letters. 42:159-167
N-Nitrosocimetidine (NCM) is a nitrosation product of cimetidine, a commonly-prescribed pharmaceutical agent. In spite of its known genotoxicity, NCM has failed to cause tumors in assays with rats and mice, but has given indications of enhancing or s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34dd890d8fff49cc47a588c8f96cf98d
https://doi.org/10.1016/0304-3835(88)90300-x
https://doi.org/10.1016/0304-3835(88)90300-x
Publikováno v:
The Journal of Organic Chemistry. 27:567-572
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed7e129a5ce252fc790c283a422bda69
https://doi.org/10.1021/jo01049a053
https://doi.org/10.1021/jo01049a053