Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Alfredo F, Braña"'
Autor:
Suhui Ye, Giovanni Ballin, Ignacio Pérez‐Victoria, Alfredo F. Braña, Jesús Martín, Fernando Reyes, José A. Salas, Carmen Méndez
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 12, Pp 2905-2916 (2022)
Abstract Coelimycin P1 and argimycins P are two types of polyketide alkaloids produced by Streptomyces coelicolor and Streptomyces argillaceus, respectively. Their biosynthesis pathways share some early steps that render very similar aminated polyket
Externí odkaz:
https://doaj.org/article/0462977fc0a8404686a8871d95ce53c2
Autor:
Suhui Ye, Brian Molloy, Ignacio Pérez-Victoria, Ignacio Montero, Alfredo F. Braña, Carlos Olano, Sonia Arca, Jesús Martín, Fernando Reyes, José A. Salas, Carmen Méndez
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8197 (2023)
Genome mining using standard bioinformatics tools has allowed for the uncovering of hidden biosynthesis gene clusters for specialized metabolites in Streptomyces genomes. In this work, we have used an alternative approach consisting in seeking “Str
Externí odkaz:
https://doaj.org/article/0bf7bf73563d4615bf03b0e677fa3456
Autor:
Aida Sarmiento-Vizcaíno, Julia Espadas, Jesús Martín, Alfredo F. Braña, Fernando Reyes, Luis A. García, Gloria Blanco
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
A cultivation-dependent approach revealed that highly diverse populations of Streptomyces were present in atmospheric precipitations from a hailstorm event sampled in February 2016 in the Cantabrian Sea coast, North of Spain. A total of 29 bioactive
Externí odkaz:
https://doaj.org/article/354295ea987d44689a59bfc28e1a0447
Autor:
Suhui Ye, Alfredo F. Braña, Javier González-Sabín, Francisco Morís, Carlos Olano, José A. Salas, Carmen Méndez
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Argimycins P are a recently identified family of polyketide alkaloids encoded by the cryptic gene cluster arp of Streptomyces argillaceus. These compounds contain either a piperideine ring, or a piperidine ring which may be fused to a five membered r
Externí odkaz:
https://doaj.org/article/fa3837eca8cc4953ae6f0c5c322a3d91
Autor:
Mónica G. Malmierca, Lorena González-Montes, Ignacio Pérez-Victoria, Carlos Sialer, Alfredo F. Braña, Raúl García Salcedo, Jesús Martín, Fernando Reyes, Carmen Méndez, Carlos Olano, José A. Salas
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Many bioactive natural products are glycosylated compounds in which the sugar components usually participate in interaction and molecular recognition of the cellular target. Therefore, the presence of sugar moieties is important, in some cases essent
Externí odkaz:
https://doaj.org/article/d5ffdf28b0c34b71b91c306cee24c81b
Autor:
Adriana Becerril, Susana Álvarez, Alfredo F Braña, Sergio Rico, Margarita Díaz, Ramón I Santamaría, José A Salas, Carmen Méndez
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0198145 (2018)
Sequencing of Streptomyces genomes has revealed they harbor a high number of biosynthesis gene cluster (BGC), which uncovered their enormous potentiality to encode specialized metabolites. However, these metabolites are not usually produced under sta
Externí odkaz:
https://doaj.org/article/6f2bb4232e054ed29f6a56661b9ced5f
Autor:
Alfredo F. Braña, Aida Sarmiento-Vizcaíno, Ignacio Pérez-Victoria, Jesús Martín, Luis Otero, Juan José Palacios-Gutiérrez, Jonathan Fernández, Yamina Mohamedi, Tania Fontanil, Marina Salmón, Santiago Cal, Fernando Reyes, Luis A. García, Gloria Blanco
Publikováno v:
Marine Drugs, Vol 17, Iss 2, p 114 (2019)
The isolation and structural elucidation of a structurally new desertomycin, designated as desertomycin G (1), with strong antibiotic activity against several clinically relevant antibiotic resistant pathogens are described herein. This new natural p
Externí odkaz:
https://doaj.org/article/da47d8869db64a3ab189db3cde0536b4
Autor:
Alfredo F. Braña, Fernando Reyes, Jesús Martín, Adriana Becerril, Ignacio Pérez-Victoria, Suhui Ye, José A. Salas, Carmen Méndez
Publikováno v:
ACS Chemical Biology. 15:1541-1553
Largimycins are hybrid nonribosomal peptide-polyketides that constitute a new group of metabolites in the leinamycin family of natural products displaying unique structural features such as containing an oxazole instead of a thiazole ring or being ox
Autor:
Raúl García-Salcedo, Rubén Álvarez-Álvarez, Carlos Olano, Librada Cañedo, Alfredo F. Braña, Carmen Méndez, Fernando de la Calle, José A. Salas
Publikováno v:
Marine Drugs, Vol 16, Iss 8, p 259 (2018)
Jomthonic acids (JAs) are a group of natural products (NPs) with adipogenic activity. Structurally, JAs are formed by a modified β-methylphenylalanine residue, whose biosynthesis involves a methyltransferase that in Streptomyces hygroscopicus has be
Externí odkaz:
https://doaj.org/article/9f015a5240174a7d865924deb7dc7bcb
Autor:
Aida Sarmiento-Vizcaíno, Alfredo F. Braña, Ignacio Pérez-Victoria, Jesús Martín, Nuria de Pedro, Mercedes de la Cruz, Caridad Díaz, Francisca Vicente, José L. Acuña, Fernando Reyes, Luis A. García, Gloria Blanco
Publikováno v:
Marine Drugs, Vol 15, Iss 9, p 271 (2017)
The present article describes a structurally novel natural product of the paulomycin family, designated as paulomycin G (1), obtained from the marine strain Micromonospora matsumotoense M-412, isolated from Cantabrian Sea sediments collected at 2000
Externí odkaz:
https://doaj.org/article/8a5133b110094ce89042bfd676ec1f14