Zobrazeno 1 - 10
of 582
pro vyhledávání: '"Alfredo Carrato"'
Autor:
Sonia Alcalá, Lara Villarino, Laura Ruiz-Cañas, José R. Couceiro, Miguel Martínez-Calvo, Adrián Palencia-Campos, Diego Navarro, Pablo Cabezas-Sainz, Iker Rodriguez-Arabaolaza, Alfonso Cordero-Barreal, Lucia Trilla-Fuertes, Juan A. Rubiolo, Sandra Batres-Ramos, Mireia Vallespinos, Cristina González-Páramos, Jéssica Rodríguez, Angelo Gámez-Pozo, Juan Ángel Fresno Vara, Sara Fra Fernández, Amparo Benito Berlinches, Nicolás Moreno-Mata, Ana María Torres Redondo, Alfredo Carrato, Patrick C. Hermann, Laura Sánchez, Susana Torrente, Miguel Ángel Fernández-Moreno, José L. Mascareñas, Bruno Sainz
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-27 (2024)
Abstract Background Previous studies by our group have shown that oxidative phosphorylation (OXPHOS) is the main pathway by which pancreatic cancer stem cells (CSCs) meet their energetic requirements; therefore, OXPHOS represents an Achille’s heel
Externí odkaz:
https://doaj.org/article/a0e8a35f5983431287f4bb493ff1d8e0
Autor:
María Angeles Vaz Salgado, Julie Earl, Victor Rodriguez Berrocal, Freddy Salge Arrieta, Ana Gomez, Juan Manuel Sepulveda-Sanchez, Ángel Perez-Nuñez, Elena Corral de la Fuente, Daniel Lourido, MaríaVillamayor, Hector Pian, Alfonso Muriel, Elisabetta Rossi, Rita Zamarchi, Alfredo Carrato, Luis Ley
Publikováno v:
Future Science OA, Vol 8, Iss 5 (2022)
Aim: Glioblastoma (GB) is an aggressive tumor type and the detection of circulating endothelial cells (CECs) in peripheral blood has been related to angiogenesis. Materials & methods: A prospective single-center pilot study of CEC detection at diagno
Externí odkaz:
https://doaj.org/article/10cbeb6d83ca4bf8842cb0bb7fc1e6a4
Autor:
Mercedes Herrera, Alberto Berral-González, Igor López-Cade, Cristina Galindo-Pumariño, Santiago Bueno-Fortes, Manuel Martín-Merino, Alfredo Carrato, Alberto Ocaña, Carolina De La Pinta, Ana López-Alfonso, Cristina Peña, Vanesa García-Barberán, Javier De Las Rivas
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-6 (2021)
Externí odkaz:
https://doaj.org/article/823a990bdb2b4b97be3a0373ad47993f
Autor:
Evangelina López de Maturana, Juan Antonio Rodríguez, Lola Alonso, Oscar Lao, Esther Molina-Montes, Isabel Adoración Martín-Antoniano, Paulina Gómez-Rubio, Rita Lawlor, Alfredo Carrato, Manuel Hidalgo, Mar Iglesias, Xavier Molero, Matthias Löhr, Christopher Michalski, José Perea, Michael O’Rorke, Victor Manuel Barberà, Adonina Tardón, Antoni Farré, Luís Muñoz-Bellvís, Tanja Crnogorac-Jurcevic, Enrique Domínguez-Muñoz, Thomas Gress, William Greenhalf, Linda Sharp, Luís Arnes, Lluís Cecchini, Joaquim Balsells, Eithne Costello, Lucas Ilzarbe, Jörg Kleeff, Bo Kong, Mirari Márquez, Josefina Mora, Damian O’Driscoll, Aldo Scarpa, Weimin Ye, Jingru Yu, PanGenEU Investigators, Montserrat García-Closas, Manolis Kogevinas, Nathaniel Rothman, Debra T Silverman, SBC/EPICURO Investigators, Demetrius Albanes, Alan A Arslan, Laura Beane-Freeman, Paige M Bracci, Paul Brennan, Bas Bueno-de-Mesquita, Julie Buring, Federico Canzian, Margaret Du, Steve Gallinger, J Michael Gaziano, Phyllis J Goodman, Marc Gunter, Loic LeMarchand, Donghui Li, Rachael E Neale, Ulrika Peters, Gloria M Petersen, Harvey A Risch, Maria José Sánchez, Xiao-Ou Shu, Mark D Thornquist, Kala Visvanathan, Wei Zheng, Stephen J Chanock, Douglas Easton, Brian M Wolpin, Rachael Z Stolzenberg-Solomon, Alison P Klein, Laufey T Amundadottir, Marc A Marti-Renom, Francisco X Real, Núria Malats
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Abstract Background Pancreatic cancer (PC) is a complex disease in which both non-genetic and genetic factors interplay. To date, 40 GWAS hits have been associated with PC risk in individuals of European descent, explaining 4.1% of the phenotypic var
Externí odkaz:
https://doaj.org/article/fd82873a71df49c79bdc3dadb14c043b
Autor:
Sonia Alcalá, Patricia Sancho, Paola Martinelli, Diego Navarro, Coral Pedrero, Laura Martín-Hijano, Sandra Valle, Julie Earl, Macarena Rodríguez-Serrano, Laura Ruiz-Cañas, Katerin Rojas, Alfredo Carrato, Laura García-Bermejo, Miguel Ángel Fernández-Moreno, Patrick C. Hermann, Bruno Sainz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The ubiquitin-like modifier ISG15 exerts post-translational protein regulation through ISGylation. Here, the authors show that ISGylation is necessary for pancreatic cancer stem cell self-renewal and tumourigenesis by supporting the recycling of non-
Externí odkaz:
https://doaj.org/article/89c3ab82d8814e75bb09a84a79555d89
Autor:
Víctor Albarrán, Jesús Chamorro, Diana Isabel Rosero, Cristina Saavedra, Ainara Soria, Alfredo Carrato, Pablo Gajate
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Immune checkpoint inhibitors have entailed a change of paradigm in the management of multiple malignant diseases and are acquiring a key role in an increasing number of clinical sceneries. However, since their mechanism of action is not limited to th
Externí odkaz:
https://doaj.org/article/a962b69d86224345b97a554c344a2b01
Autor:
Neus Martínez-Bosch, Helena Cristóbal, Mar Iglesias, Meritxell Gironella, Luis Barranco, Laura Visa, Domenico Calafato, Silvia Jiménez-Parrado, Julie Earl, Alfredo Carrato, Noemí Manero-Rupérez, Mireia Moreno, Albert Morales, Carmen Guerra, Pilar Navarro, Pablo García de Frutos
Publikováno v:
EBioMedicine, Vol 75, Iss , Pp 103797- (2022)
Summary: Background: Early diagnosis is crucial for patients with pancreatic ductal adenocarcinoma (PDAC). The AXL receptor tyrosine kinase is proteolytically processed releasing a soluble form (sAXL) into the blood stream. Here we explore the use of
Externí odkaz:
https://doaj.org/article/4de7d7f3e87f4b039869307abbfaa73f
Autor:
Konstantinos Stamatakis, Patricia Torres-Gérica, Alba Jiménez-Segovia, Edurne Ramos-Muñoz, Lorena Crespo-Toro, Patricia Fuentes, María L. Toribio, Francisco Callejas-Hernández, Alfredo Carrato, María Laura García Bermejo, Manuel Fresno
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Cyclooxygenase 2 (COX2) has been implicated in cancer development and metastasis. We have identified several COX2-regulated inflammation-related genes in human colorectal cancer cells and shown that some of them play important roles in tumor progress
Externí odkaz:
https://doaj.org/article/57c74619528c4c3eaae1892e0aaf210f
Autor:
Juan José Serrano Domingo, Teresa Alonso Gordoa, Javier Lorca Álvaro, Javier Molina-Cerrillo, Arantzazu Barquín García, Olga Martínez Sáez, Javier Burgos Revilla, Alfredo Carrato, Sara Álvarez Rodríguez
Publikováno v:
Therapeutic Advances in Urology, Vol 13 (2021)
Introduction: Androgenic deprivation therapies have been linked to the development of metabolic syndrome (MS) and cardiovascular diseases, which may lead to a poorer survival in patients with metastatic Castration-Resistant Prostate Cancer (mCRPC). W
Externí odkaz:
https://doaj.org/article/bd7dd74fc3904ca98d86d7a190c3ecec
Autor:
Elena María Vida Navas, Alberto Martínez Lorca, Aintzane Sancho Gutiérrez, Lucia Sanz Gómez, Teresa Navarro Martínez, Enrique Grande Pulido, Alfredo Carrato Mena, Pablo Gajate Borau
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Peptide receptor radionuclide therapy (PRRT) is an established treatment in advanced neuroendocrine tumors (NETs), which overexpressed somatostatin receptors. However, after progression there are a limited number of available treatments. We want to s
Externí odkaz:
https://doaj.org/article/2055b3371b7f4a068ee6fa36f91423f0