Zobrazeno 1 - 10 of 178 pro vyhledávání: '"Alfredo Cantafora"'
1
Akademický článek
Cryopreservation protocol for human biliary tree stem/progenitors, hepatic and pancreatic precursors
Autor: Lorenzo Nevi, Vincenzo Cardinale, Guido Carpino, Daniele Costantini, Sabina Di Matteo, Alfredo Cantafora, Fabio Melandro, Roberto Brunelli, Carlo Bastianelli, Camilla Aliberti, Marco Monti, Daniela Bosco, Pasquale Bartolomeo Berloco, Pierluigi Benedetti Panici, Lola Reid, Eugenio Gaudio, Domenico Alvaro
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Human biliary tree stem/progenitor cells (hBTSCs) are being used for cell therapies of patients with liver cirrhosis. A cryopreservation method was established to optimize sourcing of hBTSCs for these clinical programs and that comprises ser
Externí odkaz: https://doaj.org/article/b90fb1f259eb4becb8d0886c88ca6666
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2
Akademický článek
TGF-β signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures.
Autor: Anna Maria Lustri, Sabina Di Matteo, Alice Fraveto, Daniele Costantini, Alfredo Cantafora, Chiara Napoletano, Maria Consiglia Bragazzi, Felice Giuliante, Agostino M De Rose, Pasquale B Berloco, Gian Luca Grazi, Guido Carpino, Domenico Alvaro
Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0183932 (2017)
Cholangiocarcinoma (CCA) and its subtypes (mucin- and mixed-CCA) arise from the neoplastic transformation of cholangiocytes, the epithelial cells lining the biliary tree. CCA has a high mortality rate owing to its aggressiveness, late diagnosis and h
Externí odkaz: https://doaj.org/article/772ffd035cd74718961fcd146e9e3396
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3
Akademický článek
Abnormal splicing of ABCA1 pre-mRNA in Tangier disease due to a IVS2 +5G>C mutation in ABCA1 gene
Autor: Serena Altilia, Livia Pisciotta, Rita Garuti, Patrizia Tarugi, Alfredo Cantafora, Laura Calabresi, Jacopo Tagliabue, Sergio Maccari, Franco Bernini, Ilaria Zanotti, Carlo Vergani, Stefano Bertolini, Sebastiano Calandra
Publikováno v: Journal of Lipid Research, Vol 44, Iss 2, Pp 254-264 (2003)
Two point mutations of ABCA1 gene were found in a patient with Tangier disease (TD): i) G>C in intron 2 (IVS2 +5G>C) and ii) c.844 C>T in exon 9 (R282X). The IVS2 +5G>C mutation was also found in the brother of another deceased TD patient, but not in
Externí odkaz: https://doaj.org/article/eb6e958ad20e4b4cb77ab5e79e99a6b5
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4
Akademický článek
Simple detection of a point mutation in LDL receptor gene causing familial hypercholesterolemia in southern Italy by allele-specific polymerase chain reaction
Autor: Alfredo Cantafora, Ida Blotta, Elisabetta Mercuri, Sebastiano Calandra, Stefano Bertolini
Publikováno v: Journal of Lipid Research, Vol 39, Iss 5, Pp 1101-1105 (1998)
Polymerase chain reaction (PCR) amplification of specific alleles allowed the rapid detection of a point mutation (missense Gly528 → Asp) in exon 11 of the low density lipoprotein receptor gene which was otherwise not detectable by exon amplificati
Externí odkaz: https://doaj.org/article/2dab7a4b5d9249ea99e90d7a844ae4e6
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5
The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity
Autor: Monica Mischitelli, Gianluca Mennini, Massimo Rossi, Antonio Molinaro, Flaminia Ferri, Maria Eva Argenziano, Alessandro Corsi, Mara Riminucci, Quirino Lai, Sergio Morini, Alfredo Cantafora, G. Spadetta, Eugenio Gaudio, Francesco Pugliese, Guido Carpino, Simona Parisse, Simone Carotti, Stefano Ginanni Corradini
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6100, p 6100 (2021)
Volume 22
Issue 11
In nonalcoholic steatohepatitis animal models, an increased lipid droplet size in hepatocytes is associated with fibrogenesis. Hepatocytes with large droplet (Ld-MaS) or small droplet (Sd-MaS) macrovesicular steatosis may coexist in the human liver,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e9564f7d78e0d6dd4c3eb0f8f3e242
http://europepmc.org/articles/PMC8200978
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6
Profiles of Cancer Stem Cell Subpopulations in Cholangiocarcinomas
Autor: Paolo Onori, Gian Luca Grazi, Maria Consiglia Bragazzi, Anastasia Renzi, A. Torrice, Domenico Alvaro, Chiara Napoletano, Gianfranco Alpini, Antonio Franchitto, Alfredo Cantafora, Eugenio Gaudio, Nicola Caporaso, Felice Giuliante, Agostino M. Derose, Vincenzo Cardinale, Lola M. Reid, A. Fraveto, Guido Carpino, Giuseppe D'Argenio
Publikováno v: The American Journal of Pathology. 185:1724-1739
Cholangiocarcinomas (CCAs) comprise a mucin-secreting form, intrahepatic or perihilar, and a mixed form located peripherally. We characterized cancer stem cells (CSCs) in CCA subtypes and evaluated their cancerogenic potential. CSC markers were inves
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217a9686e4a42df32b6f45bc19a399e3
https://doi.org/10.1016/j.ajpath.2015.02.010
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7
TGF-β signaling is an effective target to impair survival and induce apoptosis of human cholangiocarcinoma cells: A study on human primary cell cultures
Autor: Felice Giuliante, Chiara Napoletano, Daniele Costantini, Maria Consiglia Bragazzi, Guido Carpino, Alfredo Cantafora, Agostino Maria De Rose, Sabina Di Matteo, Domenico Alvaro, Pasquale Berloco, Anna Maria Lustri, A. Fraveto, Gian Luca Grazi
Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0183932 (2017)
PLoS ONE
Cholangiocarcinoma (CCA) and its subtypes (mucin- and mixed-CCA) arise from the neoplastic transformation of cholangiocytes, the epithelial cells lining the biliary tree. CCA has a high mortality rate owing to its aggressiveness, late diagnosis and h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8d9b8266cc697dea398a4f2efeb745
http://hdl.handle.net/11573/1011694
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8
The Fas/Fas ligand apoptosis pathway underlies immunomodulatory properties of human biliary tree stem/progenitor cells
Autor: Roberto Brunelli, Anto De Pol, Chiara Napoletano, Carlo Bastianelli, Alessandra Pisciotta, Raffaele Gentile, Gianluca Carnevale, Andrea Cossarizza, Lara Gibellini, Sara De Biasi, Eugenio Gaudio, Vincenzo Cardinale, Alfredo Cantafora, Massimo Riccio, Pasquale Berloco, Domenico Alvaro, Guido Carpino
Publikováno v: Journal of Hepatology. 61:1097-1105
Background & Aims Human biliary tree stem/progenitor cells (hBTSCs) are multipotent epithelial stem cells, easily obtained from the biliary tree, with the potential for regenerative medicine in liver, biliary tree, and pancreas diseases. Recent repor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f32232e757e5503cd22574024d54ce
https://doi.org/10.1016/j.jhep.2014.06.016
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9
Recipient perioperative cholesterolaemia and graft cholesterol metabolism gene expression predict liver transplant outcome
Autor: Alfredo Cantafora, M. Siciliano, Manuela Merli, E. Poli, Lucia Parlati, Alessandro Corsi, Annarita Vestri, Massimo Rossi, Fabio Melandro, Adolfo Francesco Attili, Gianluca Mennini, Antonio Molinaro, Stefano Ginanni Corradini, Pasquale Berloco, Paolo Bianco, Edmondo Falleti, Davide Bitetto, Pierluigi Toniutto
Publikováno v: Liver International. 34:e290-e301
Background & Aims We analysed for the first time whether recipient perioperative serum total cholesterol (sTC) concentration is associated with liver transplantation outcome. Methods We studied noncholestatic cirrhotics submitted to primary deceased-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207a1efd182523c4f9d7eb74a63248d1
https://doi.org/10.1111/liv.12351
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