Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Alfredo Molinolo"'
Autor:
Rebecca A. Shatsky, Hemali Batra-Sharma, Teresa Helsten, Richard B. Schwab, Emily I. Pittman, Minya Pu, Elizabeth Weihe, Emanuela M. Ghia, Laura Z. Rassenti, Alfredo Molinolo, Betty Cabrera, James B. Breitmeyer, George F. Widhopf, Karen Messer, Catriona Jamieson, Thomas J. Kipps, Barbara A. Parker
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Background Zilovertamab is a humanized monoclonal antibody targeting ROR1, an onco-embryonic antigen expressed by malignant cells of a variety of solid tumors, including breast cancer. A prior phase 1 study showed that zilovertamab was well
Externí odkaz:
https://doaj.org/article/0486bdf60d074a82b6fba59959ed172b
Autor:
Rebecca A. Shatsky, Hemali Batra-Sharma, Teresa Helsten, Richard B. Schwab, Emily I. Pittman, Minya Pu, Elizabeth Weihe, Emanuela M. Ghia, Laura Z. Rassenti, Alfredo Molinolo, Betty Cabrera, James B. Breitmeyer, George F. Widhopf II, Karen Messer, Catriona Jamieson, Thomas J. Kipps, Barbara A. Parker
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/e6112c11579145ef905f2712d4ff134a
Autor:
Carlos J Diaz Osterman, Duygu Ozmadenci, Elizabeth G Kleinschmidt, Kristin N Taylor, Allison M Barrie, Shulin Jiang, Lisa M Bean, Florian J Sulzmaier, Christine Jean, Isabelle Tancioni, Kristen Anderson, Sean Uryu, Edward A Cordasco, Jian Li, Xiao Lei Chen, Guo Fu, Marjaana Ojalill, Pekka Rappu, Jyrki Heino, Adam M Mark, Guorong Xu, Kathleen M Fisch, Vihren N Kolev, David T Weaver, Jonathan A Pachter, Balázs Győrffy, Michael T McHale, Denise C Connolly, Alfredo Molinolo, Dwayne G Stupack, David D Schlaepfer
Publikováno v:
eLife, Vol 8 (2019)
Gene copy number alterations, tumor cell stemness, and the development of platinum chemotherapy resistance contribute to high-grade serous ovarian cancer (HGSOC) recurrence. Stem phenotypes involving Wnt-β-catenin, aldehyde dehydrogenase activities,
Externí odkaz:
https://doaj.org/article/7193db572cdc40948c8a07915a6afd96
Autor:
Marzia Scortegagna, Yuanning Du, Linda M. Bradley, Kun Wang, Alfredo Molinolo, Eytan Ruppin, Rabi Murad, Ze'ev A. Ronai
Publikováno v:
Cancer Research.
Cellular components of the tumor microenvironment, including myeloid cells, play important roles in the progression of lung adenocarcinoma (LUAD) and its response to therapy. Here, we characterize the function of the ubiquitin ligases Siah1a/2 in reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaadab17b9c35c7972109c7b45fd8d61
https://doi.org/10.1158/0008-5472.can-23-0258
https://doi.org/10.1158/0008-5472.can-23-0258
Autor:
Yardena Samuels, Carlos López-Otín, Jeffrey E. Gershenwald, Michael A. Davies, Steven A. Rosenberg, Pedro Cruz, Isabel Cardenas-Navia, Jimmy C. Lin, Alfredo Molinolo, Cristina G. Viloria, Todd D. Prickett, Xiaomu Wei
PDF file - 431K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d5bd504b4d563f9027682fb0e3a544
https://doi.org/10.1158/1541-7786.22518732
https://doi.org/10.1158/1541-7786.22518732
Autor:
Yardena Samuels, Carlos López-Otín, Jeffrey E. Gershenwald, Michael A. Davies, Steven A. Rosenberg, Pedro Cruz, Isabel Cardenas-Navia, Jimmy C. Lin, Alfredo Molinolo, Cristina G. Viloria, Todd D. Prickett, Xiaomu Wei
The disintegrin-metalloproteinases with thrombospondin domains (ADAMTS) genes have been suggested to function as tumor suppressors as several have been found to be epigenetically silenced in various cancers. We performed a mutational analysis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11703b25d3b8e3bc4e02fa87898149be
https://doi.org/10.1158/1541-7786.c.6542100
https://doi.org/10.1158/1541-7786.c.6542100
Autor:
Roberto Weigert, J. Silvio Gutkind, Alfredo Molinolo, Vyomesh Patel, Kantima Leelahavanichkul, Andrius Masedunskas, Jamie Thompson, Kamil Rechache, Panomwat Amornphimoltham
MOV file - 313K, Intravital imaging of tumor cells migration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a151df75f29785acf690027ec836db77
https://doi.org/10.1158/1078-0432.22451648.v1
https://doi.org/10.1158/1078-0432.22451648.v1
Autor:
Roberto Weigert, J. Silvio Gutkind, Alfredo Molinolo, Vyomesh Patel, Kantima Leelahavanichkul, Andrius Masedunskas, Jamie Thompson, Kamil Rechache, Panomwat Amornphimoltham
PDF file - 82K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2667b3d1d513e8983035004ed776a8
https://doi.org/10.1158/1078-0432.22451657
https://doi.org/10.1158/1078-0432.22451657
Autor:
Roberto Weigert, J. Silvio Gutkind, Alfredo Molinolo, Vyomesh Patel, Kantima Leelahavanichkul, Andrius Masedunskas, Jamie Thompson, Kamil Rechache, Panomwat Amornphimoltham
MOV file - 313K, Rab25 expression reduces protrusion at the plasma membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1710faf4d051d0d1461c45d468c154fd
https://doi.org/10.1158/1078-0432.22451645.v1
https://doi.org/10.1158/1078-0432.22451645.v1
Autor:
J. Silvio Gutkind, Vyomesh Patel, Alfredo Molinolo, Kantima Leelahavanichkul, Panomwat Amornphimoltham
Purpose: The activation of Akt/mammalian target of rapamycin (mTOR) pathway represents a frequent event in squamous cell carcinoma (SCC) progression, thus raising the possibility of using specific mTOR inhibitors for the treatment of SCC patients. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8fad7919e5a02397f92a736164a3386
https://doi.org/10.1158/1078-0432.c.6517095
https://doi.org/10.1158/1078-0432.c.6517095