Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Alfredo, Ferro"'
TMBcalc: a computational pipeline for identifying pan-cancer Tumor Mutational Burden gene signatures
Autor:
Grete Francesca Privitera, Salvatore Alaimo, Anna Caruso, Alfredo Ferro, Stefano Forte, Alfredo Pulvirenti
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background:In the precision medicine era, identifying predictive factors to select patients most likely to benefit from treatment with immunological agents is a crucial and open challenge in oncology.Methods:This paper presents a pan-cancer analysis
Externí odkaz:
https://doaj.org/article/6c66c76d46664a4a9817ec92c3d87ff3
Autor:
Alessandro La Ferlita, Salvatore Alaimo, Giovanni Nigita, Rosario Distefano, Joal D. Beane, Philip N. Tsichlis, Alfredo Ferro, Carlo M. Croce, Alfredo Pulvirenti
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108810- (2024)
Summary: tRNA-derived ncRNAs are a heterogeneous class of non-coding RNAs recently proposed to be active regulators of gene expression and be involved in many diseases, including cancer. Consequently, several online resources on tRNA-derived ncRNAs h
Externí odkaz:
https://doaj.org/article/df8d8d9b250e4871b51ccf310172e060
Autor:
Ilaria Cosentini, Daniele Filippo Condorelli, Giorgio Locicero, Alfredo Ferro, Alfredo Pulvirenti, Vincenza Barresi, Salvatore Alaimo
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/7449cfa806ef4b568a8952ae87df7f5e
Autor:
Elisabetta Sciacca, Anna E. A. Surace, Salvatore Alaimo, Alfredo Pulvirenti, Felice Rivellese, Katriona Goldmann, Alfredo Ferro, Vito Latora, Costantino Pitzalis, Myles J. Lewis
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-14 (2022)
Abstract Background To determine whether gene-gene interaction network analysis of RNA sequencing (RNA-Seq) of synovial biopsies in early rheumatoid arthritis (RA) can inform our understanding of RA pathogenesis and yield improved treatment response
Externí odkaz:
https://doaj.org/article/e0a65c61fe5740cdb09f8f6ab51d5801
Autor:
Alessandro Muscolino, Antonio Di Maria, Rosaria Valentina Rapicavoli, Salvatore Alaimo, Lorenzo Bellomo, Fabrizio Billeci, Stefano Borzì, Paolo Ferragina, Alfredo Ferro, Alfredo Pulvirenti
Publikováno v:
Applied Network Science, Vol 7, Iss 1, Pp 1-24 (2022)
Abstract Background The rapidly increasing biological literature is a key resource to automatically extract and gain knowledge concerning biological elements and their relations. Knowledge Networks are helpful tools in the context of biological knowl
Externí odkaz:
https://doaj.org/article/48b62a382556467a9680b35db8851a96
Autor:
Naomi I. Maria, Rosaria Valentina Rapicavoli, Salvatore Alaimo, Evelyne Bischof, Alessia Stasuzzo, Jantine A.C. Broek, Alfredo Pulvirenti, Bud Mishra, Ashley J. Duits, Alfredo Ferro
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e14115- (2023)
The current, rapidly diversifying pandemic has accelerated the need for efficient and effective identification of potential drug candidates for COVID-19. Knowledge on host-immune response to SARS-CoV-2 infection, however, remains limited with few dru
Externí odkaz:
https://doaj.org/article/0ed24cbe7de84a848aaf54c9a501957a
Autor:
Gioacchino P. Marceca, Rosario Distefano, Luisa Tomasello, Alessandro Lagana, Francesco Russo, Federica Calore, Giulia Romano, Marina Bagnoli, Pierluigi Gasparini, Alfredo Ferro, Mario Acunzo, Qin Ma, Carlo M. Croce, Giovanni Nigita
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-11 (2021)
Abstract MicroRNAs (miRNAs) are regulatory small non-coding RNAs that function as translational repressors. MiRNAs are involved in most cellular processes, and their expression and function are presided by several factors. Amongst, miRNA editing is a
Externí odkaz:
https://doaj.org/article/35c91d7ed5b145ce98b819e875e1d78d
Publikováno v:
Applied Network Science, Vol 6, Iss 1, Pp 1-22 (2021)
Abstract Temporal networks are graphs where each edge is associated with a timestamp denoting when two nodes interact. Temporal Subgraph Isomorphism (TSI) aims at retrieving all the subgraphs of a temporal network (called target) matching a smaller t
Externí odkaz:
https://doaj.org/article/daadffa02d8f443080d41c6d29c7ce7a
Autor:
Alessandro La Ferlita, Salvatore Alaimo, Sebastiano Di Bella, Emanuele Martorana, Georgios I. Laliotis, Francesco Bertoni, Luciano Cascione, Philip N. Tsichlis, Alfredo Ferro, Roberta Bosotti, Alfredo Pulvirenti
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background RNA-Seq is a well-established technology extensively used for transcriptome profiling, allowing the analysis of coding and non-coding RNA molecules. However, this technology produces a vast amount of data requiring sophisticated c
Externí odkaz:
https://doaj.org/article/4e360b93746c4bf4a5e05628bf5e1e7a
Autor:
Antonio Di Maria, Salvatore Alaimo, Lorenzo Bellomo, Fabrizio Billeci, Paolo Ferragina, Alfredo Ferro, Alfredo Pulvirenti
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The inference of novel knowledge and new hypotheses from the current literature analysis is crucial in making new scientific discoveries. In bio-medicine, given the enormous amount of literature and knowledge bases available, the automatic gain of kn
Externí odkaz:
https://doaj.org/article/53cd42e240df454a840a529f899e21ca