Zobrazeno 1 - 10
of 1 099
pro vyhledávání: '"Alfredo, Falcone"'
Autor:
Luigi Coltelli, Giacomo Allegrini, Paola Orlandi, Chiara Finale, Andrea Fontana, Luna Chiara Masini, Marco Scalese, Giada Arrighi, Maria Teresa Barletta, Ermelinda De Maio, Marta Banchi, Elisabetta Fini, Patrizia Guidi, Giada Frenzilli, Sara Donati, Simona Giovannelli, Lucia Tanganelli, Barbara Salvadori, Lorenzo Livi, Icro Meattini, Ilaria Pazzagli, Marco Di Lieto, Mirco Pistelli, Virginia Casadei, Antonella Ferro, Samanta Cupini, Francesca Orlandi, Damiana Francesca, Giulia Lorenzini, Leonardo Barellini, Alfredo Falcone, Alessandro Cosimi, Guido Bocci
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract To investigate pharmacogenetic interactions among VEGF-A, VEGFR-2, IL-8, HIF-1α, EPAS-1, and TSP-1 SNPs and their role on progression-free survival (PFS) in metastatic breast cancer (MBC) patients treated with bevacizumab plus first-line pa
Externí odkaz:
https://doaj.org/article/ddb3a8574ac74c6f9118cd6ec4935bea
Autor:
Jingyuan Wang, Joshua Millstein, Yan Yang, Sebastian Stintzing, Hiroyuki Arai, Francesca Battaglin, Natsuko Kawanishi, Shivani Soni, Wu Zhang, Christoph Mancao, Chiara Cremolini, Tianshu Liu, Volker Heinemann, Alfredo Falcone, Lin Shen, Heinz-Josef Lenz
Publikováno v:
EClinicalMedicine, Vol 57, Iss , Pp 101827- (2023)
Summary: Background: Antiangiogenic drug (AAD)-triggered oxygen and nutrient depletion through suppression of angiogenesis switches glucose-dependent to lipid-dependent metabolism. Blocking fatty acid oxidation can enhance AAD-mediated anti-tumor eff
Externí odkaz:
https://doaj.org/article/369c666a028b48c587ea629fca3a1f39
Autor:
Madiha Naseem, Shu Cao, Dongyun Yang, Joshua Millstein, Alberto Puccini, Fotios Loupakis, Sebastian Stintzing, Chiara Cremolini, Ryuma Tokunaga, Francesca Battaglin, Shivani Soni, Martin D. Berger, Afsaneh Barzi, Wu Zhang, Alfredo Falcone, Volker Heinemann, Heinz-Josef Lenz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract KRAS status serves as a predictive biomarker of response to treatment in metastatic colorectal cancer (mCRC). We hypothesize that complex interactions between multiple pathways contribute to prognostic differences between KRAS wild-type and
Externí odkaz:
https://doaj.org/article/bcef797c1a0241b78b98c0ecbb71d350
Autor:
Carlotta Antoniotti, Beatrice Borelli, Daniele Rossini, Filippo Pietrantonio, Federica Morano, Lisa Salvatore, Sara Lonardi, Federica Marmorino, Stefano Tamberi, Salvatore Corallo, Giampaolo Tortora, Francesca Bergamo, Di Stefano Brunella, Alessandra Boccaccino, Elisa Grassi, Patrizia Racca, Emiliano Tamburini, Giuseppe Aprile, Roberto Moretto, Luca Boni, Alfredo Falcone, Chiara Cremolini
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background Immune checkpoint inhibitors (ICIs) reported remarkable achievements in several solid tumours. However, in metastatic colorectal cancer (mCRC) promising results are limited to patients with deficient mismatch repair/microsatellite
Externí odkaz:
https://doaj.org/article/9d9f7151e67a49a2a5095a5c6c078498
Autor:
David Gómez-Ulloa, Mayur Amonkar, Smita Kothari, Winson Y. Cheung, Ian Chau, John R. Zalcberg, Núria Lara Suriñach, Alfredo Falcone
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Second-line (2 L) chemotherapies for advanced or metastatic gastric cancer have shown improved survival but there is no commonly accepted standard of care. This study examines real-world patient characteristics, treatment patterns
Externí odkaz:
https://doaj.org/article/6952bf68cc7e4fff80b28bf3f7411d85
Autor:
Simone Guadagni, Niccolò Furbetta, Gregorio Di Franco, Matteo Palmeri, Desirée Gianardi, Matteo Bianchini, Martina Guadagnucci, Luca Pollina, Gianluca Masi, Chiara Cremolini, Alfredo Falcone, Franco Mosca, Giulio Di Candio, Luca Morelli
Publikováno v:
Journal of Minimal Access Surgery, Vol 16, Iss 2, Pp 160-165 (2020)
Background: Although minimally invasive surgery (MIS) of the liver is increasingly widespread, its role in the treatment of colorectal liver metastasis (CRLM) remains uncertain. In this setting, the role of robotic-assisted surgery (RAS) has not been
Externí odkaz:
https://doaj.org/article/fe15a4ff561e4e3aa3d34bd1af28f47d
Autor:
Yi Xiao, Chiara Cremolini, Fotios Loupakis, Alfredo Falcone, Natsuko Kawanishi, Christoph Mancao, Bodour Salhia, Shannon M Mumenthaler, Daniel J Weisenberger, Gangning Liang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immunogenic cell death (ICD) is a tumor cell death involving both innate and adaptive immune responses. Given published findings that oxaliplatin, but not irinotecan, drives ICD, we investigated whether single nucleotide polymorphisms (SNP
Externí odkaz:
https://doaj.org/article/63cb3449cb6048b68ddf421f2efdf186
Autor:
Timothy Price, Chiara Cremolini, Alfredo Falcone, Eric Van Cutsem, Julien Taieb, Jean-Marc Phelip, Jean-Baptiste Bachet, Lucjan Wyrwicz, Fabienne Portales, Ahmet Ozet, Irfan Cicin, Dan Atlan, Martin Becquart, Loick Vidot, Nadjat Mounedji
Publikováno v:
ESMO Open, Vol 5, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/f278b869784d4e0e9c442dc4a12a9eff
Autor:
Timothy Price, Chiara Cremolini, Alfredo Falcone, Eric Van Cutsem, Julien Taieb, Jean-Marc Phelip, Jean-Baptiste Bachet, Lucjan Wyrwicz, Fabienne Portales, Ahmet Ozet, Irfan Cicin, Dan Atlan, Martin Becquart, Loick Vidot, Nadjat Mounedji
Publikováno v:
ESMO Open, Vol 5, Iss 3 (2020)
Background In RECOURSE (, trifluridine/tipiracil significantly improved overall survival and progression-free survival (PFS) versus placebo in patients with pretreated metastatic colorectal cancer (mCRC). PRECONNECT was designed to further characteri
Externí odkaz:
https://doaj.org/article/d4363a641e6c4b95ba550f4e125c6b83
Autor:
Andrea Cacciato Insilla, Caterina Vivaldi, Mirella Giordano, Enrico Vasile, Carla Cappelli, Emanuele Kauffmann, Niccolò Napoli, Alfredo Falcone, Ugo Boggi, Daniela Campani
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Neoadjuvant therapy represents an increasingly used strategy in pancreatic cancer, and this means that more pancreatic resections need to be evaluated for therapy effect. Several grading systems have been proposed for the histological assessment of t
Externí odkaz:
https://doaj.org/article/ab4da1a908af4999baa3ca66fe0f62b9