Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Alfred W Legasse"'
Autor:
Alec J Hirsch, Jessica L Smith, Nicole N Haese, Rebecca M Broeckel, Christopher J Parkins, Craig Kreklywich, Victor R DeFilippis, Michael Denton, Patricia P Smith, William B Messer, Lois M A Colgin, Rebecca M Ducore, Peta L Grigsby, Jon D Hennebold, Tonya Swanson, Alfred W Legasse, Michael K Axthelm, Rhonda MacAllister, Clayton A Wiley, Jay A Nelson, Daniel N Streblow
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006317 (2017)
[This corrects the article DOI: 10.1371/journal.ppat.1006219.].
Externí odkaz:
https://doaj.org/article/116ea9460e3f48fe8753fbc0acc79393
Autor:
Alec J Hirsch, Jessica L Smith, Nicole N Haese, Rebecca M Broeckel, Christopher J Parkins, Craig Kreklywich, Victor R DeFilippis, Michael Denton, Patricia P Smith, William B Messer, Lois M A Colgin, Rebecca M Ducore, Peta L Grigsby, Jon D Hennebold, Tonya Swanson, Alfred W Legasse, Michael K Axthelm, Rhonda MacAllister, Clayton A Wiley, Jay A Nelson, Daniel N Streblow
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006219 (2017)
Zika virus (ZIKV), an emerging flavivirus, has recently spread explosively through the Western hemisphere. In addition to symptoms including fever, rash, arthralgia, and conjunctivitis, ZIKV infection of pregnant women can cause microcephaly and othe
Externí odkaz:
https://doaj.org/article/55de2daddda341f08d68238e192dcd1f
Autor:
Benjamin J Burwitz, Daniel Malouli, Benjamin N Bimber, Jason S Reed, Abigail B Ventura, Meaghan H Hancock, Luke S Uebelhoer, Amruta Bhusari, Katherine B Hammond, Renee G Espinosa Trethewy, Alex Klug, Alfred W Legasse, Michael K Axthelm, Jay A Nelson, Byung S Park, Daniel N Streblow, Scott G Hansen, Louis J Picker, Klaus Früh, Jonah B Sacha
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1006014 (2016)
Cytomegaloviruses (CMV) are highly species-specific due to millennia of co-evolution and adaptation to their host, with no successful experimental cross-species infection in primates reported to date. Accordingly, full genome phylogenetic analysis of
Externí odkaz:
https://doaj.org/article/7f89ac2e54d24ee7a16db764f546ae92
Autor:
Elizabeth R Sturgill, Daniel Malouli, Scott G Hansen, Benjamin J Burwitz, Seongkyung Seo, Christine L Schneider, Jennie L Womack, Marieke C Verweij, Abigail B Ventura, Amruta Bhusari, Krystal M Jeffries, Alfred W Legasse, Michael K Axthelm, Amy W Hudson, Jonah B Sacha, Louis J Picker, Klaus Früh
Publikováno v:
PLoS Pathogens, Vol 12, Iss 8, p e1005868 (2016)
The natural killer cell receptor NKG2D activates NK cells by engaging one of several ligands (NKG2DLs) belonging to either the MIC or ULBP families. Human cytomegalovirus (HCMV) UL16 and UL142 counteract this activation by retaining NKG2DLs and US18
Externí odkaz:
https://doaj.org/article/ab867361cfd74334a156f85967627cb8
Autor:
Helen L. Wu, Whitney Weber, Shaheed A. Abdulhaqq, Christine Shriver-Munsch, Tonya Swanson, Mina Northrup, Kimberly Armantrout, Heidi Price, Mitchell Robertson-LeVay, Jason S. Reed, Katherine B. Bateman, Benjamin N. Bimber, Stephanie L. Junell, Rhonda MacAllister, Alfred W. Legasse, Michael K. Axthelm, Cassandra Moats, Jeremy Smedley, Theodore R. Hobbs, Lauren D. Martin, Gabrielle Meyers, Richard T. Maziarz, Benjamin J. Burwitz, Jeffrey J. Stanton, Jonah B. Sacha
Publikováno v:
Journal of Virus Eradication, Vol 5, Iss , Pp 19- (2019)
Externí odkaz:
https://doaj.org/article/aa992c8462d9478f90e5cf5c5077def3
Autor:
Gabriela M. Webb, Shengbin Li, Gwantwa Mwakalundwa, Joy M. Folkvord, Justin M. Greene, Jason S. Reed, Jeffery J. Stanton, Alfred W. Legasse, Theodore Hobbs, Lauren D. Martin, Byung S. Park, James B. Whitney, Emily K. Jeng, Hing C. Wong, Douglas F. Nixon, R. Brad Jones, Elizabeth Connick, Pamela J. Skinner, Jonah B. Sacha
Publikováno v:
Blood Advances, Vol 2, Iss 2, Pp 76-84 (2018)
Abstract: Sequestering of latent HIV in follicular helper T cells within B-cell follicles that largely exclude cytotoxic T cells is a major barrier to cellular immune-based approaches to eradicate HIV. Here, we show that the clinical-grade human inte
Externí odkaz:
https://doaj.org/article/eefee46bd3354844aa52e77eb0fb72eb
Autor:
Helen L. Wu, Kathleen Busman-Sahay, Whitney C. Weber, Courtney M. Waytashek, Carla D. Boyle, Katherine B. Bateman, Jason S. Reed, Joseph M. Hwang, Christine Shriver-Munsch, Tonya Swanson, Mina Northrup, Kimberly Armantrout, Heidi Price, Mitch Robertson-LeVay, Samantha Uttke, Mithra R. Kumar, Emily J. Fray, Sol Taylor-Brill, Stephen Bondoc, Rebecca Agnor, Stephanie L. Junell, Alfred W. Legasse, Cassandra Moats, Rachele M. Bochart, Joseph Sciurba, Benjamin N. Bimber, Michelle N. Sullivan, Brandy Dozier, Rhonda P. MacAllister, Theodore R. Hobbs, Lauren D. Martin, Angela Panoskaltsis-Mortari, Lois M.A. Colgin, Robert F. Siliciano, Janet D. Siliciano, Jacob D. Estes, Jeremy V. Smedley, Michael K. Axthelm, Gabrielle Meyers, Richard T. Maziarz, Benjamin J. Burwitz, Jeffrey J. Stanton, Jonah B. Sacha
Publikováno v:
Immunity.
Autor:
Alfred W. Legasse, Mina Northrup, Michael K. Axthelm, Tonya Swanson, Cassandra Moats, Whitney C. Weber, Jeremy Smedley, Kimberly Armantrout, Lauren D. Martin, Christine Shriver-Munsch, Helen L. Wu, Katherine B. Bateman, Justin M. Greene, Richard T. Maziarz, Benjamin J. Burwitz, Theodore R. Hobbs, Jonah B. Sacha, Nicholas Maier
Publikováno v:
J Clin Apher
Macaques are physiologically relevant animal models of human immunology and infectious disease that have provided key insights and advanced clinical treatment in transplantation, vaccinology, and HIV/AIDS. However, the small size of macaques is a stu
Autor:
Emily Ainslie, Romas Geleziunas, Yuan Li, Joseph Hesselgesser, Yoshinori Fukazawa, Randy Fast, Paul T. Edlefsen, Bhavesh Borate, Scott G. Hansen, Louis J. Picker, Alfred W. Legasse, Derick M. Duell, Mukta Vaidya, Abigail B. Ventura, Afam A. Okoye, Roxanne M. Gilbride, Richard Lum, Haesun Park, Michael K. Axthelm, Julia C. Ford, William J. Bosche, Jeffrey D. Lifson, Colette M. Hughes, Rebecca Shoemaker, David Morrow, Kelli Oswald
Publikováno v:
Nature Medicine. 24:1430-1440
Prophylactic vaccination of rhesus macaques with rhesus cytomegalovirus (RhCMV) vectors expressing simian immunodeficiency virus (SIV) antigens (RhCMV/SIV) elicits immune responses that stringently control highly pathogenic SIV infection, with subseq
Autor:
Emily Ainslie, Colette M. Hughes, Alan Aderem, Louis J. Picker, Scott G. Hansen, Thomas G. Evans, Michele Stone, Shannon L. Planer, Abigail B. Ventura, Daniel Malouli, Smitha Shankar, Guangwu Xu, Daniel E. Zak, Aurelio Bonavia, Roxanne M. Gilbride, Parker Rundstrom, Alfred W. Legasse, Lynn M. Amon, Christina Armstrong, Lauren Herlache, Kurt T. Randall, Robert C. Zweig, Martin Messerle, Dominick Laddy, John M. Turner, Klaus Früh, Haesun Park, Michael A. Jarvis, Emily E. Marshall, Andrea N. Selseth, Miranda Fischer, Joseph Valvo, Jackie Braun, Andrew W. Sylwester, Galit Alter, Michael K. Axthelm, Julia C. Ford, Lenette L. Lu, Paul T. Edlefsen, Matthew S. Lewis
Publikováno v:
Nature Medicine. 24:130-143
Despite widespread use of the bacille Calmette-Guerin (BCG) vaccine, tuberculosis (TB) remains a leading cause of global mortality from a single infectious agent (Mycobacterium tuberculosis or Mtb). Here, over two independent Mtb challenge studies, w