Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alfred Simkin"'
High-throughput genotyping of Plasmodium vivax in the Peruvian Amazon via molecular inversion probes
Autor:
Zachary R. Popkin-Hall, Karamoko Niaré, Rebecca Crudale, Alfred Simkin, Abebe A. Fola, Juan F. Sanchez, Danielle L. Pannebaker, David J. Giesbrecht, Isaac E. Kim, Özkan Aydemir, Jeffrey A. Bailey, Hugo O. Valdivia, Jonathan J. Juliano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Plasmodium vivax transmission occurs throughout the tropics and is an emerging threat in areas of Plasmodium falciparum decline, causing relapse infections that complicate treatment and control. Targeted sequencing for P. falciparum has been
Externí odkaz:
https://doaj.org/article/1b39464e805c493facfa4c51b116776b
Autor:
Kelly Carey-Ewend, Zachary R. Popkin-Hall, Alfred Simkin, Meredith Muller, Chris Hennelly, Wenqiao He, Kara A. Moser, Claudia Gaither, Karamoko Niaré, Farhang Aghakanian, Sindew Feleke, Bokretsion G. Brhane, Fernandine Phanzu, Melchior Mwandagalirwa Kashamuka, Ozkan Aydemir, Colin J. Sutherland, Deus S. Ishengoma, Innocent M. Ali, Billy Ngasala, Albert Kalonji, Antoinette Tshefu, Jonathan B. Parr, Jeffrey A. Bailey, Jonathan J. Juliano, Jessica T. Lin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Plasmodium ovale curtisi (Poc) and Plasmodium ovale wallikeri (Pow) are relapsing malaria parasites endemic to Africa and Asia that were previously thought to represent a single species. Amid increasing detection of ovale malaria in sub-Saha
Externí odkaz:
https://doaj.org/article/29132de2891747e2b0b623ecdeb93afc
Publikováno v:
PLoS Genetics, Vol 16, Iss 2, p e1008285 (2020)
MicroRNAs (miRNAs) control the abundance of the majority of the vertebrate transcriptome. The recognition sequences, or target sites, for bilaterian miRNAs are found predominantly in the 3' untranslated regions (3'UTRs) of mRNAs, and are amongst the
Externí odkaz:
https://doaj.org/article/f51c468e3af2431198f0813e862eff0e
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 2, p e1008285 (2020)
PLoS Genetics, Vol 16, Iss 2, p e1008285 (2020)
MicroRNAs (miRNAs) control the abundance of the majority of the vertebrate transcriptome. The recognition sequences, or target sites, for bilaterian miRNAs are found predominantly in the 3′ untranslated regions (3′UTRs) of mRNAs, and are amongst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7a144941eb9c8cf207bf4960326657
http://europepmc.org/articles/PMC7018135
http://europepmc.org/articles/PMC7018135
Publikováno v:
Evolution. 67:1081-1090
Uncontrolled transposable element (TE) insertions and excisions can cause chromosome breaks and mutations with dramatic deleterious effects. The PIWI interacting RNA (piRNA) pathway functions as an adaptive TE silencing system during germline develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0969ac44f3a8b2e9facfe920d267045
https://doi.org/10.1111/evo.12011
https://doi.org/10.1111/evo.12011
Autor:
Doreen M. Floss, Rene Geissler, Jürgen Scheller, Alfred Simkin, Andrew Grimson, Ravi K. Patel, Elizabeth A. Fogarty
Publikováno v:
Genesdevelopment. 30(9)
3′-untranslated regions (UTRs) specify post-transcriptional fates of mammalian messenger RNAs (mRNAs), yet knowledge of the underlying sequences and mechanisms is largely incomplete. Here, we identify two related novel 3′ UTR motifs in mammals th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4e3ce5ff094bba141d7b7f3e553753
https://pubmed.ncbi.nlm.nih.gov/27151978
https://pubmed.ncbi.nlm.nih.gov/27151978
Publikováno v:
Molecular biology and evolution. 31(7)
The first microRNAs (miRNAs) were identified as essential, conserved regulators of gene expression, targeting the same genes across nearly all bilaterians. However, there are also prominent examples of conserved miRNAs whose functions appear to have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b9bc57fa9fa4d636652e752119c7f7
https://pubmed.ncbi.nlm.nih.gov/24723422
https://pubmed.ncbi.nlm.nih.gov/24723422
Publikováno v:
The Journal of heredity. 103(2)
The recent availability of whole-genome sequencing data affords tremendous power for statistical inference. With this, there has been great interest in the development of polymorphism-based approaches for the estimation of population genetic paramete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e367c0ab5691ae0f958ce98d05ebfa
https://pubmed.ncbi.nlm.nih.gov/22246406
https://pubmed.ncbi.nlm.nih.gov/22246406
Publikováno v:
RNA biology. 8(4)
The functional significance of microRNA-9 (miR-9) during evolution is evidenced by its conservation at the nucleotide level from flies to humans but not its diverse expression patterns. Recent studies in several model systems reveal that miR-9 can re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192022f23c66b84f36f3343e04d0f7c6
https://pubmed.ncbi.nlm.nih.gov/21697652
https://pubmed.ncbi.nlm.nih.gov/21697652