Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Alfred M, Cohen"'
Publikováno v:
Journal of Biological Chemistry. 293:18770-18778
Cancer is a set of diseases characterized by uncontrolled cell growth. In certain cancers of the gastrointestinal tract, the adenomatous polyposis coli (APC) tumor suppressor gene is altered in either germline or somatic cells and causes formation of
Autor:
N. Jewel Samadder, Alfred M. Cohen, Robert Hüneburg, Eric Van Cutsem, Elizabeth Bruckheimer, Francesc Balaguer, Paul E. Wise, James M. Church, Elena M. Stoffel, Ramona M. Lim, Carol A. Burke, Patrick M. Lynch, Evelien Dekker, Michelle Boytim, Wei Du
Publikováno v:
American Journal of Gastroenterology. 115:S129-S129
Autor:
N. Jewel Samadder, Elena M. Stoffel, Alfred M. Cohen, Francesc Balaguer, Robert Hüneburg, Patrick M. Lynch, Steven Gallinger, Christian P. Strassburg, Ramona M. Lim, Carol A. Burke, Samir Gupta, Evelien Dekker
Publikováno v:
Gastroenterology. 156:S-79
Publikováno v:
Expert Review of Gastroenterology & Hepatology. 6:507-517
To reduce the morbidity and mortality from colorectal cancer, current clinical practice focuses on screening for early detection and polypectomy as a form of secondary prevention, complemented with surgical interventions when appropriate. No pharmace
Publikováno v:
Clinical Colorectal Cancer. 11:88-92
This review explores the current available literature regarding the role of neoadjuvant therapy for upper locally advanced rectal cancers (≥10 cm-15 cm). Although there is a paucity of data evaluating the outcomes of preoperative chemoradiation for
Autor:
Mark Gimbel, Francis Barany, Philip B. Paty, Jurg Ott, Zhaoshi Zeng, Garrett M. Nash, Mackevin I. Ndubuisi, Alfred M. Cohen, Daniel R. Nathanson
Publikováno v:
Annals of Surgical Oncology. 17:416-424
We examined two genetic markers established early in colorectal tumor development, microsatellite instability (MSI) and mutation of the KRAS proto-oncogene, to see if these genetic changes influence metastatic disease progression and survival.MSI and
Autor:
W. Douglas Wong, Axel Hoos, Jose G. Guillem, Bruce D. Minsky, Philip B. Paty, Jinru Shia, David S. Klimstra, Alfred M. Cohen, Aviram Nissan, Alexander Stojadinovic
Publikováno v:
Journal of Clinical Oncology. 24:4078-4084
Purpose Treatment of rectal cancer with neoadjuvant radiotherapy has been shown to reduce local recurrence and improve overall survival. The role of chemoradiotherapy in patients with T2, N0 and early T3, N0 rectal cancer, treated by radical surgery
Autor:
Paul S Dudrick, Alexander Stojadinovic, Philip B. Paty, Nancy E. Kemeny, Antonio I. Picon, Yuman Fong, Peter J. Allen, Aviram Nissan, Alfred M. Cohen, Joseph Espat, Leah Ben-Porat
Publikováno v:
Journal of the American College of Surgeons. 201:57-65
Hepatic arterial infusion pump chemotherapy is an important component in the treatment of patients with hepatic metastases. Successful use of a hepatic arterial infusion pump requires a low technical complication rate. We evaluated the complications
Autor:
Warren E. Enker, Philip B. Paty, W. Douglas Wong, Martin R. Weiser, David B. Chessin, Bruce D. Minsky, Leonard B. Saltz, Jose G. Guillem, Alfred M. Cohen
Publikováno v:
Journal of the American College of Surgeons. 200:876-882
Background Preoperative combined modality therapy followed by total mesorectal excision has emerged as the optimal treatment paradigm for locally advanced rectal cancer (T3 to 4, N1, or both). But its impact on postoperative complications has not bee
Autor:
Philip B. Paty, Wilbur B. Bowne, Alfred M. Cohen, Byrne Lee, Warren E. Enker, Martin R. Weiser, W. Douglas Wong, Jose G. Guillem, Leah Ben-Porat, Jinru Shia
Publikováno v:
Diseases of the Colon & Rectum. 48:897-909
Locoregional recurrence after resection of colon carcinoma is an uncommon and difficult clinical problem. Outcome data to guide surgical management are limited. This investigation was undertaken to review our experience with surgical resection for pa