Výsledky vyhledávání - "Alfred L, Fisher"

Akademický článek

Pyoverdine, a siderophore from Pseudomonas aeruginosa, translocates into C. elegans, removes iron, and activates a distinct host response

Autor: Donghoon Kang, Daniel R. Kirienko, Phillip Webster, Alfred L. Fisher, Natalia V. Kirienko

Publikováno v: Virulence, Vol 9, Iss 1, Pp 804-817 (2018)

Pseudomonas aeruginosa, a re-emerging, opportunistic human pathogen, encodes a variety of virulence determinants. Pyoverdine, a siderophore produced by this bacterium, is essential for pathogenesis in mammalian infections. This observation is general

Externí odkaz: https://doaj.org/article/b8be3977d5f84589be2fd41d4fd975ed

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Akademický článek

CRISPR-mediated genome editing and human diseases

Autor: Liquan Cai, Alfred L. Fisher, Haochu Huang, Zijian Xie

Publikováno v: Genes and Diseases, Vol 3, Iss 4, Pp 244-251 (2016)

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has emerged as a powerful technology for genome editing and is now widely used in basic biomedical research to explore gene function. More recently, this technology has bee

Externí odkaz: https://doaj.org/article/5d227910294f418db065169bf02006e8

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The HEART Camp Exercise Intervention Improves Exercise Adherence, Physical Function, and Patient-Reported Outcomes in Adults With Preserved Ejection Fraction Heart Failure

Autor: Merry L. Lindsey, Kevin A. Kupzyk, Scott Lundgren, Joseph F. Norman, Bunny Pozehl, Alfred L. Fisher, Steven J. Keteyian, Windy Alonso

Publikováno v: J Card Fail

Background Despite exercise being one of few strategies to improve outcomes for individuals with heart failure with preserved ejection fraction (HFpEF), exercise clinical trials in HFpEF are plagued by poor interventional adherence. Over the last 2 d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c746cffb268f6843a0061c698e602f
https://doi.org/10.1016/j.cardfail.2021.09.003

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Data from Atg5 Regulates Phenethyl Isothiocyanate–Induced Autophagic and Apoptotic Cell Death in Human Prostate Cancer Cells

Autor: Shivendra V. Singh, Yu Jiang, Alfred L. Fisher, Anna A. Powolny, Dong Xiao, Eun-Ryeong Hahm, Ajay Bommareddy

Phenethyl isothiocyanate (PEITC) is a promising cancer chemopreventive agent but the mechanism of its anticancer effect is not fully understood. We now show, for the first time, that PEITC treatment triggers Atg5-dependent autophagic and apoptotic ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::075376465a6c3bb31526d5623153bea5
https://doi.org/10.1158/0008-5472.c.6499620.v1

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HspB1 Overexpression Improves Life Span and Stress Resistance in an Invertebrate Model

Autor: Erin Munkáscy, Alfred L. Fisher, Tali Gidalevitz, James D. Lechleiter, Maruf Khan, Courtney Carroll Alexander, Tamara Fraker, Karl A. Rodriguez, Haven Tillmon, Habil Zare, Jessica Scheirer, Damian Lozano, Deborah M. Holstein

Publikováno v: The Journals of Gerontology: Series A. 77:268-275

To explore the role of the small heat shock protein beta 1 (HspB1, also known as Hsp25 in rodents and Hsp27 in humans) in longevity, we created a Caenorhabiditis elegans model with a high level of ubiquitous expression of the naked mole-rat HspB1 pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10a64be53632d9f04297168d41993c6
https://doi.org/10.1093/gerona/glab296

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