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pro vyhledávání: '"Alfred G. George"'
Autor:
Sneha Adusumilli, Hope Woods, Charles R. Sanders, Jens Meiler, Georg Kuenze, Carlos G. Vanoye, Reshma R. Desai, Eli Fritz McDonald, Alfred G. George, Kathryn R. Brewer
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
The function of the voltage-gated KCNQ1 potassium channel is regulated by co-assembly with KCNE auxiliary subunits. KCNQ1-KCNE1 channels generate the slow delayed rectifier current, IKs, which contributes to the repolarization phase of the cardiac ac
Publikováno v:
Biophysical Journal. (2):311a
Mutations in ATP1A3 have been identified as the genetic cause of alternating hemiplegia of childhood (AHC). Loss of Na/K-ATPase activity has been proposed as the likely functional consequence of mutations, but specific mechanisms have not been demons