Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Alfred G Knudson"'
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76746 (2013)
OBJECTIVE:To determine the expression patterns of NF-κB regulators and target genes in clear cell renal cell carcinoma (ccRCC), their correlation with von Hippel Lindau (VHL) mutational status, and their association with survival outcomes. METHODS:M
Externí odkaz:
https://doaj.org/article/7aa75c666b5346caaf6d3008e6454414
Autor:
Alfred G. Knudson, Levy Kopelovich, Eric Ross, Henry T. Lynch, James A. Crowell, Margie L. Clapper, Anthony T. Yeung, Emmanuelle Nicolas, Kerry S. Campbell, Sharon Howard, Mary Daly, Yan Zhou, Carolyn Slater, Betsy Bove, Lisa Vanderveer, Elena Caretti, Karthik Devarajan, Suraj Peri, Andrew K. Godwin, Alfonso Bellacosa
We hypothesized that cells bearing a single inherited “hit” in a tumor suppressor gene express an altered mRNA repertoire that may identify targets for measures that could delay or even prevent progression to carcinoma. We report here on the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f028d0affc83af02d79b29ac06cda94
https://doi.org/10.1158/1940-6207.c.6544698.v1
https://doi.org/10.1158/1940-6207.c.6544698.v1
Autor:
Alfred G. Knudson, Levy Kopelovich, Eric Ross, Henry T. Lynch, James A. Crowell, Margie L. Clapper, Anthony T. Yeung, Emmanuelle Nicolas, Kerry S. Campbell, Sharon Howard, Mary Daly, Yan Zhou, Carolyn Slater, Betsy Bove, Lisa Vanderveer, Elena Caretti, Karthik Devarajan, Suraj Peri, Andrew K. Godwin, Alfonso Bellacosa
Perspective on this Article from Altered Gene Expression in Morphologically Normal Epithelial Cells from Heterozygous Carriers of BRCA1 or BRCA2 Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321a5a3ec1c10e98ac9d026d8ac1cbdf
https://doi.org/10.1158/1940-6207.22525347
https://doi.org/10.1158/1940-6207.22525347
Autor:
Alfred G. Knudson, Levy Kopelovich, Eric Ross, Henry T. Lynch, James A. Crowell, Margie L. Clapper, Anthony T. Yeung, Emmanuelle Nicolas, Kerry S. Campbell, Sharon Howard, Mary Daly, Yan Zhou, Carolyn Slater, Betsy Bove, Lisa Vanderveer, Elena Caretti, Karthik Devarajan, Suraj Peri, Andrew K. Godwin, Alfonso Bellacosa
Supplementary Methods, Tables 1-3, Figure 1 from Altered Gene Expression in Morphologically Normal Epithelial Cells from Heterozygous Carriers of BRCA1 or BRCA2 Mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4002f5049475c5c1c10bf559d42b76f0
https://doi.org/10.1158/1940-6207.22525344
https://doi.org/10.1158/1940-6207.22525344
Autor:
Emmanuelle Nicolas, Cathy D. Vocke, Joseph R. Testa, Craig W. Menges, Eric A. Ross, Robert G. Uzzo, Suraj Peri, Kerry S. Campbell, Karthik Devarajan, Christopher J. Ricketts, Eleonora Sementino, James A. Crowell, Rossella Tricarico, Alfonso Bellacosa, Mitchell Cheung, Elena Caretti, Peggy Conrad, Sharon Howard, Lisa Vanderveer, Elizabeth P. Henske, Andrew K. Godwin, W. Marston Linehan, Alfred G. Knudson, Levy Kopelovich, Margie L. Clapper, Anthony T. Yeung
Publikováno v:
Oncotarget
// Suraj Peri 1 , Elena Caretti 2 , Rossella Tricarico 2 , Karthik Devarajan 1 , Mitchell Cheung 3 , Eleonora Sementino 3 , Craig W. Menges 3 , Emmanuelle Nicolas 3 , Lisa A. Vanderveer 4 , Sharon Howard 5 , Peggy Conrad 6 , James A. Crowell 7 , Kerr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3019690a2ab8180bf4a2b3044b29f657
https://pubmed.ncbi.nlm.nih.gov/27682873
https://pubmed.ncbi.nlm.nih.gov/27682873
Autor:
Alfred G. Knudson, Harry S. Cooper, Yin A. He, Anthony T. Yeung, Steven H. Seeholzer, Renata A. Coudry, James A. Crowell, David Cheng, Bruce M. Boman, Sharon Howard, Levy Kopelovich, Elena L. Blagoi, Alfonso Bellacosa, Dawn M. Riddle, Emmanuelle Nicolas, Bhavinkumar B. Patel, Xin-Ming Li, Maketa P. Dixon, Peggy Conrad
Publikováno v:
Oncotarget
Here we compared the proteomes of primary fibroblast cultures derived from morphologically normal colonic mucosa of familial adenomatous polyposis (FAP) patients with those obtained from unaffected controls. The expression signature of about 19% of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3231a779ec73123b30b956e1bc3ca500
http://europepmc.org/articles/PMC3195363
http://europepmc.org/articles/PMC3195363
Autor:
Andrew K. Godwin, Henry T. Lynch, Mary B. Daly, Levy Kopelovich, Lisa Vanderveer, James A. Crowell, Betsy Bove, Karthik Devarajan, Carolyn M. Slater, Alfred G. Knudson, Elena Caretti, Eric A. Ross, Suraj Peri, Kerry S. Campbell, Yan Zhou, Margie L. Clapper, Anthony T. Yeung, Emmanuelle Nicolas, Alfonso Bellacosa, Sharon Howard
Publikováno v:
Cancer Prevention Research. 3:48-61
We hypothesized that cells bearing a single inherited “hit” in a tumor suppressor gene express an altered mRNA repertoire that may identify targets for measures that could delay or even prevent progression to carcinoma. We report here on the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1199866c0684479ca91aa9acb8c151
https://doi.org/10.1158/1940-6207.capr-09-0078
https://doi.org/10.1158/1940-6207.capr-09-0078
Autor:
John M. Maris, Alfred G. Knudson
Publikováno v:
Nature reviews. Cancer. 15(2)
Heritable germline mutations in major cancer genes generally lead to a restricted pattern of tissue-specific malignancies, yet many of the same mutations frequently occur somatically in a broad range of spontaneous neoplasms affecting different organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d24c53cbad32b5422527be2e3c93129
https://pubmed.ncbi.nlm.nih.gov/25688405
https://pubmed.ncbi.nlm.nih.gov/25688405
Publikováno v:
Proceedings of the National Academy of Sciences. 103:17874-17879
We previously concluded, from our analysis of the published data of other investigators, that the yield of germ-line and somatic mutations after exposure to ionizing radiation is parabolically related to the logarithm of the dose-rate at which a give
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8184f26db6ab8e91c8b88633f8659012
https://doi.org/10.1073/pnas.0607995103
https://doi.org/10.1073/pnas.0607995103
Autor:
Harry S. Cooper, Eric Ross, Alfonso Bellacosa, Christos Patriotis, Margie L. Clapper, Radka Stoyanova, John J. Upson, Alfred G. Knudson, Bruce M. Boman
Publikováno v:
Journal of Cellular Physiology. 201:366-373
Analysis of cell-specific gene expression patterns using microarrays can reveal genes that are differentially expressed in diseased and normal tissue, as well as identify genes associated with specialized cellular functions. However, the cellular het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61597c7a4785d3212d4c05d8a38423cf
https://doi.org/10.1002/jcp.20073
https://doi.org/10.1002/jcp.20073