Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Alfred F. Michael"'
Autor:
N. Gunnar Westberg, Alfred F. Michael
Publikováno v:
Acta Medica Scandinavica. 194:39-47
Autor:
Clifford E. Kashtan, Elizabeth A. Wayner, Bing Zhou, Youngki Kim, Wei-Wei Fan, Effie C. Tsilibary, Uma Krishnamurti, Alfred F. Michael
Publikováno v:
Journal of the American Society of Nephrology. 12:758-766
Puromycin aminonucleoside (PAN)-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, but the mechanism of PAN's effect is not completely understood. Because PAN injection into rats results in retraction of glomerular ep
Autor:
Aristidis S. Charonis, Bill Gleason, Bing Zhou, Todd R. Nelson, Metaxia Vlassi, Alfred F. Michael, Clifford E. Kashtan
Publikováno v:
Journal of the American Society of Nephrology. 11:658-668
Tubulointerstitial nephritis antigen (TIN-Ag) is a recently described basement membrane glycoprotein reactive with autoantibodies in some forms of immunologically mediated human tubulointerstitial nephritis. This report presents the complete cDNA and
Autor:
Curtis L. Atkin, Joyce C. Denison, Yoav Segal, Yoshikazu Sado, Satoshi Sasaki, Yoshifumi Ninomiya, Clifford E. Kashtan, David F. Barker, Martin C. Gregory, Jing Zhou, Youngki Kim, Bing Zhou, Alfred F. Michael, Wei Wei Fan
Publikováno v:
Matrix Biology. 17:279-291
COL4A5 mutations causing X-linked Alport syndrome (XLAS) are frequently associated with absence of the alpha3, alpha4,alpha5 and alpha6 chains of type IV collagen from basement membranes and increased amounts of the alpha1(IV) and alpha2(IV) chains i
Publikováno v:
Connective Tissue Research. 37:53-60
Tubulointerstitial nephritis antigen (TIN-ag) is a 58 kDa glycoprotein restricted within the kidney to basement membranes underlying the epithelium of Bowman's capsule and proximal and distal tubules. Autoantibody formation against this component has
Immunochemical and biochemical evidence for distinct basement membrane heparan sulfate proteoglycans
Publikováno v:
Journal of Biological Chemistry. 268:7261-7269
Two antigenically and structurally related heparan sulfate proteoglycans (HSPG), with masses of 200 and 350 kDa, have been isolated and characterized from bovine renal tubular basement membranes (BTBM) using DEAE-Sephacel, octyl-Sepharose CL-4B, and
Publikováno v:
Kidney International. 41:1629-1637
Immunochemical studies of the Alport antigen. The Alport antigen, a component of normal glomerular basement membranes (GBM) which is absent in Alport familial nephritis, is characterized as a 26 kD non-collagenous (NCI) peptide identified by a monocl
Publikováno v:
Kidney International. 38:925-930
Gene mapping in Alport families with different basement membrane antigenic phenotypes. The present study was undertaken to determine whether differences among Alport kindreds in the antigenic phenotypes of their basement membranes result from defects
Publikováno v:
Pediatric Nephrology. 4:523-532
Alport syndrome, an inherited disorder of the kidney, eye and ear, has fascinated nephrologists, pathologists, and geneticists for nearly a century. With the recent application of molecular biochemical and genetic techniques, this mysterious disease
Autor:
Bing Zhou, Paraskevi V. Kitsiou, Alfred F. Michael, Effie C. Tsilibary, William G. Stetler-Stevenson, Wei Wei Fan, Athina K. Tzinia
Publikováno v:
American journal of physiology. Renal physiology. 284(4)
In cultured human glomerular epithelial cells (HGEC), 25 mM glucose resulted in decreased expression of α3-, α2-, and β1-integrins and increased expression of α5- and αvβ3-integrins. This change was accompanied by decreased binding of HGEC to t