Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alfred E Slanetz"'
Autor:
Walter Barry, Farzonai Muzaffar, Sriram Srivatsa, Ground Entrance, Ryan Campbell, Abenezer Abera, Alfred E Slanetz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/f9557055f72e43849d28d81cfbe5a628
Publikováno v:
Cancer Research. 83:4067-4067
Immune checkpoint inhibitors, such as anti-PD1 antibodies, have revolutionized cancer immunotherapy. Their success demonstrates that a patient’s own T cells recognize and treat cancer. However, anti-PD1 therapy is most effective in the treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40aa1e053c5aa6e016a66b3a09fa56a8
https://doi.org/10.1158/1538-7445.am2023-4067
https://doi.org/10.1158/1538-7445.am2023-4067
Autor:
Stephen E. Maher, Alfred E. Slanetz, Marie T. Jelonek, Maripat Corr, Sergei Khilko, Alfred L. M. Bothwell, Basel K. al-Ramadi, Lisa F. Boyd, Young Sang Kim, David H. Margulies
Publikováno v:
Science. 268:115-117
The critical discriminatory event in the activation of T lymphocytes bearing alpha beta T cell receptors (TCRs) is their interaction with a molecular complex consisting of a peptide bound to a major histocompatibility complex (MHC)-encoded class I or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731a6d14ed475e8d4871a76edb45444e
https://doi.org/10.1126/science.7701331
https://doi.org/10.1126/science.7701331
Publikováno v:
European journal of immunology. 21(1)
Structural and functional analysis of T cell receptor (TcR)-ligand binding would be greatly advanced by the availability of an intact, assembled TcR in soluble form. We have produced such a molecule, by splicing the extracellular domains of a TcR to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925f5b3e7ec0f3c8b60eaad00b32aff5
https://pubmed.ncbi.nlm.nih.gov/1671358
https://pubmed.ncbi.nlm.nih.gov/1671358
Autor:
Ralph L. Brinster, Donal B. Murphy, Charles A. Janeway, Alfred E. Slanetz, David Lo, Richard A. Flavell, Satyajit Rath
Publikováno v:
Nature. 338:765-768
THE repertoire of receptors expressed by peripheral T cells is the result of two selective events that occur during intrathymic development. Positive selection expands cells able to recognize foreign peptides presented by self MHC molecules, and nega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14365e7059e01d856a2e9505d95c7d86
https://doi.org/10.1038/338765a0
https://doi.org/10.1038/338765a0