Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Alfred E, Chang"'
Autor:
Elizabeth Gensterblum-Miller, Qiao Li, Alfred E Chang, Ying Xin, Andrew C Chang, Assel Issabekova, Dyke McEwen, J Chad Brenner, Hannah Dobson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/61f95c153ea349e4a55eb68b312046ee
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Controversial views regarding the roles of B cells in tumor immunity have existed for several decades. However, more recent studies have focused on its positive properties in antitumor immunity. Many studies have demonstrated a close association of t
Externí odkaz:
https://doaj.org/article/914d1a9be40848ef9d4e1b428f64af01
Autor:
Kunle Odunsi, Takaaki Oba, Hans Minderman, Kenichi Makino, Ryutaro Kajihara, Toshihiro Yokoi, Ryoko Araki, Masumi Abe, Alfred E Chang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Background Dendritic cells (DCs) are a promising therapeutic target in cancer immunotherapy given their ability to prime antigen-specific T cells, and initiate antitumor immune response. A major obstacle for DC-based immunotherapy is the difficulty t
Externí odkaz:
https://doaj.org/article/b0b53910545d499abfe3d46f4a5b5925
Autor:
Marisa E, Aikins, You, Qin, Hannah E, Dobson, Alireza Hassani, Najafabadi, Kexing, Lyu, Yao, Xu, Ying, Xin, Anna, Schwendeman, Max S, Wicha, Alfred E, Chang, Qiao, Li, James J, Moon
Publikováno v:
Journal of Controlled Release. 351:872-882
One of the major reasons for poor cancer outcomes is the existence of cancer stem cells (CSCs). CSCs are a small subpopulation of tumor cells that can self-renew, differentiate into the majority of tumor cells, and maintain tumorigenicity. As CSCs ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a879b08e947765880a78f86b4c5ec067
https://doi.org/10.1016/j.jconrel.2022.09.061
https://doi.org/10.1016/j.jconrel.2022.09.061
Autor:
Jessica L. Thompson, Brandy R. Sinco, Rachel L. McCaffrey, Alfred E. Chang, Michael S. Sabel, Lesly A. Dossett, Tasha M. Hughes, Jacqueline S. Jeruss
Publikováno v:
Journal of Surgical Oncology. 127:18-27
Sentinel node biopsy (SLNB) is not routinely recommended for patients undergoing prophylactic mastectomy (PM), yet omission remains a subject of debate among surgeons. A modern patient cohort was examined to determine occult malignancy (OM) incidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19aed4057ebd120a5acc265ddc31bf93
https://doi.org/10.1002/jso.27088
https://doi.org/10.1002/jso.27088
Autor:
Qiao Li, Max S. Wicha, Alfred E. Chang, Elaine M. Hurt, Shiang Huang, Yangyang Hu, Yalei Zhang, Wenlong Shao, Runming Jin, Archana Thakur, Lawrence Lum, Yong Zhu, Ming Lin, Shasha Ruan
Figure S1 indicated that ITGB4-targeted cancer immunotherapies did not cause severe immunotherapy-related toxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e615494d0eea9ac4c3b9f405c7e5aef2
https://doi.org/10.1158/0008-5472.22425139.v1
https://doi.org/10.1158/0008-5472.22425139.v1
Autor:
Sami N. Malek, Daniel J. Klionsky, Alfred E. Chang, Mark S. Kaminski, Shaomeng Wang, Mehmet Yildiz, Kamlai Saiya-Cork, Denzil Bernard, Luke F. Peterson, Meiyan Jin, Zhang Xiao Ying
Table S1. Yeast strains; Table S2. Primers used for yeasts mutagenesis; Table S3: B-factor for GTP/GDP during MD simulations with WT RRAGC or with point Mutations; Table S4: Energy contribution of each residue (kcal/mol) to GTP and GDP binding; Figur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fe19f670e032adf0c68c9ab0a5776f
https://doi.org/10.1158/1078-0432.22462820
https://doi.org/10.1158/1078-0432.22462820
Autor:
Sami N. Malek, Daniel J. Klionsky, Alfred E. Chang, Mark S. Kaminski, Shaomeng Wang, Mehmet Yildiz, Kamlai Saiya-Cork, Denzil Bernard, Luke F. Peterson, Meiyan Jin, Zhang Xiao Ying
Purpose: This study was performed to further our understanding of the biological and genetic basis of follicular lymphoma and to identify potential novel therapy targets.Experimental Design: We analyzed previously generated whole exome sequencing dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ba15e2bb2ce65b3101efebf5a36bb6
https://doi.org/10.1158/1078-0432.c.6525221.v1
https://doi.org/10.1158/1078-0432.c.6525221.v1
Autor:
Qiao Li, Max S. Wicha, Alfred E. Chang, Elaine M. Hurt, Shiang Huang, Yangyang Hu, Yalei Zhang, Wenlong Shao, Runming Jin, Archana Thakur, Lawrence Lum, Yong Zhu, Ming Lin, Shasha Ruan
Table S1 demonstrated that ITGB4-targeted immunotherapies with or without anti-PD-L1 did not significantly affect hematopoiesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040df3b6f3460ea656a7ea8d6fe3a34d
https://doi.org/10.1158/0008-5472.22425136.v1
https://doi.org/10.1158/0008-5472.22425136.v1
Autor:
Qiao Li, Max S. Wicha, Alfred E. Chang, Elaine M. Hurt, Shiang Huang, Yangyang Hu, Yalei Zhang, Wenlong Shao, Runming Jin, Archana Thakur, Lawrence Lum, Yong Zhu, Ming Lin, Shasha Ruan
Integrin β4 (ITGB4) has been shown to play an important role in the regulation of cancer stem cells (CSC). Immune targeting of ITGB4 represents a novel approach to target this cell population, with potential clinical benefit. We developed two immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a99e2fdcd82575ad7450cd88202c566
https://doi.org/10.1158/0008-5472.c.6511954.v1
https://doi.org/10.1158/0008-5472.c.6511954.v1