Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alfred D. Lakeman"'
Autor:
Richard J. Whitley, John B. Fiveash, L. Burt Nabors, Alfred D. Lakeman, Matthias Karrasch, Cheryl A. Palmer, Hui-Chien Kuo, Jacqueline N. Parker, Alan B. Cantor, James M. Markert, Jennifer M. Coleman, Michael Markiewicz, G. Yancey Gillespie, Bonita S. Agee, Ralph R. Weichselbaum, Shantanu N Razdan, Anette Knoll
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 22(5)
G207, a mutant herpes simplex virus (HSV) type 1, is safe when inoculated into recurrent malignant glioma. We conducted a phase 1 trial of G207 to demonstrate the safety of stereotactic intratumoral administration when given 24 hours prior to a singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18033397865a3512f3131db808f2c297
https://pubmed.ncbi.nlm.nih.gov/24572293
https://pubmed.ncbi.nlm.nih.gov/24572293
Autor:
James J. Cody, E. R. Kern, George Yancey Gillespie, Jennifer M. Coleman, S. C. Cartner, Richard J. Whitley, Debra C. Quenelle, Trenton R. Schoeb, Kathleen H. Price, Parker Jn, Cheryl A. Palmer, James M. Markert, Alfred D. Lakeman
Herpes simplex virus 1 (HSV-1) mutants that lack the γ 1 34.5 gene are unable to replicate in the central nervous system but maintain replication competence in dividing cell populations, such as those found in brain tumors. We have previously demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2beeb8eb03bc2cf0b803716dae085a
https://europepmc.org/articles/PMC3347348/
https://europepmc.org/articles/PMC3347348/
Autor:
Eunice Braz, Wenquan Wang, Richard J. Whitley, Jacqueline N. Parker, George Yancey Gillespie, Louis B. Nabors, Peter Liechty, Matthias Karrasch, Michael Markiewicz, Cheryl A. Palmer, Shanna Gaston, James M. Markert, Alfred D. Lakeman
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 17(1)
We have previously demonstrated safety of G207, a doubly mutated (deletion of both gamma(1)34.5 loci, insertional inactivation of U(L)39) herpes simplex virus (HSV) for patients stereotactically inoculated in enhancing portions of recurrent malignant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b4990827ffcc2775311c673d3b43bc
https://pubmed.ncbi.nlm.nih.gov/19116635
https://pubmed.ncbi.nlm.nih.gov/19116635
Autor:
Pablo J. Sánchez, Seng-Jaw Soong, Gail J. Demmler, Richard J. Whitley, David W. Kimberlin, Richard F. Jacobs, Russell D. Bradford, Alfred D. Lakeman, Suresh B. Boppana, William J. Britt, Gretchen A. Cloud
Publikováno v:
The Journal of infectious diseases. 191(2)
Objective The study sought to determine the relationship between cytomegalovirus (CMV) viremia during early infancy and clinical and laboratory outcome events, particularly hearing loss in infants with symptomatic congenital CMV infection involving t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9062b4367414a772531fba6e68e4769
https://pubmed.ncbi.nlm.nih.gov/15609232
https://pubmed.ncbi.nlm.nih.gov/15609232
Autor:
Russell W. Steele, S. Burchett, Yvonne J. Bryson, Mobeen H. Rathore, D. Powell, Wendy Vaudry, Alfred D. Lakeman, Ann M. Arvin, R. B. Van Dyke, Russell B. Van Dyke, Sergio Stagno, John S. Bradley, S. J. Soong, Ross E. McKinney, William C. Gruber, M. Shelton, Peter D. Reuman, J. Kinney, Charles G. Prober, Gail J. Demmler, Stuart P. Adler, J. Gross, A. Lakeman, S. Laudert, C. Laughlin, Leonard B. Weiner, W. Gruber, P. Diaz, Pamela S. Diaz, Stuart E. Starr, C. Sander, A. Arvin, Tasnee Chonmaitree, Harry L. Keyserling, Joan L. Robinson, Richard J. Whitley, Mary L. Kumar, Charles T. Leach, R. Whitley, John F. Modlin, Sandra K. Burchett, R. Jacobs, Andrea Kovacs, Gregory A. Storch, L. Stanberry, Dwight A. Powell, Stephen A. Spector, E. Leistikow, David W. Kimberlin, Richard F. Jacobs, Seng Jaw Soong, James F. Bale, Lawrence Corey, Cody Meissner, M. De Sierra, D. Kimberlin, M. Kumar, Robert F. Pass
Publikováno v:
The Pediatric infectious disease journal. 15(3)
Background. Neonatal herpes simplex virus (HSV) infections limited to the skin, eyes and mouth (SEM) can result in neurologic impairment. A direct correlation exists between the development of neurologic deficits and the frequency of cutaneous HSV re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c751cd13d2be5d7147a9ffc19bbce0e3
https://pubmed.ncbi.nlm.nih.gov/8852914
https://pubmed.ncbi.nlm.nih.gov/8852914
Autor:
M. A. Pfaller, Donald Nicholson, Trish M. Perl, Richard J. Hollis, Alfred D. Lakeman, Gloria A. Hunter, Thomas H. Haugen, Richard P. Wenzel, Richard J. Whitley
Publikováno v:
Annals of internal medicine. 117(7)
Excerpt Herpes simplex virus type 1 (HSV-1) infection has reportedly been transmitted via contaminated secretions from an infected patient to susceptible health care workers, producing a finger inf...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480124840c468636a5604ffdac3b4657
https://pubmed.ncbi.nlm.nih.gov/1524332
https://pubmed.ncbi.nlm.nih.gov/1524332
Autor:
Alfred D. Lakeman, Matthias Karrasch, George Yancey Gillespie, Richard J. Whitley, James M. Markert, Cheryl A. Palmer, Peter Liechty, Louis B. Nabors, E. Braz, Parker Jn
Publikováno v:
Journal of Clinical Oncology. 27:2042-2042
2042 Background: G207 is a doubly mutated (deletion of both γ134.5 loci, insertional inactivation of UL39) herpes simplex virus (HSV)-1. Safety and efficacy of intracerebral inoculations of G207 to patients suffering from recurrent malignant gliomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57eb0b9bc35d11ad394c65e81dd2dbae
https://doi.org/10.1200/jco.2009.27.15_suppl.2042
https://doi.org/10.1200/jco.2009.27.15_suppl.2042
Autor:
Charles A. Alford, Stanley A. Plotkin, Dwight A. Powell, C Laughlin, G Caddell, Sandra K. Burchett, Alfred D. Lakeman, C V Sumaya, Richard J. Whitley, Lawrence Corey, J Benton, Andre J. Nahmias, Kathryn M. Edwards, Soong Sj, Stuart E. Starr, Ann M. Arvin, Sergio Stagno, Richard F. Jacobs, Charles G. Prober
Publikováno v:
International Journal of Gynecology & Obstetrics. 37:68-69
Background. In a controlled trial comparing acyclovir with vidarabine in the treatment of neonatal herpes simplex virus (HSV) infection, we found no significant difference between the treatments in adjusted mortality and morbidity. Hence, we sought t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92560560c54deafcdf24e565fa3169af
https://doi.org/10.1016/0020-7292(92)90998-x
https://doi.org/10.1016/0020-7292(92)90998-x
Autor:
Stuart E. Starr, J Benton, Richard J. Whitley, James D. Connor, Sandra K. Burchett, Soong Sj, Alfred D. Lakeman, Charles A. Alford, C Laughlin, Dwight A. Powell, Andre J. Nahmias, Stanley A. Plotkin, Richard F. Jacobs, Lawrence Corey, N Watson, Ann M. Arvin, G Caddell, Sergio Stagno, Charles G. Prober
Publikováno v:
International Journal of Gynecology & Obstetrics. 37:68-68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24af4d29f30dbb84a2f89eeb76240b7f
https://doi.org/10.1016/0020-7292(92)90997-w
https://doi.org/10.1016/0020-7292(92)90997-w
Autor:
Stephen M. Nigida Jr., Lauren G. Wolfe, Charles A. Alford, Lawrence A. Falk, Friedrich Deinhardt, Alfred D. Lakeman
Publikováno v:
Journal of Infectious Diseases. 132:582-586
Two adult and two neonatal cotton-topped marmosets and two neonatal white-lipped marmosets (Saguinus species) were inoculated with 10(7) plaque-forming units of cytomegalovirus (Colburn strain). No overt clinical disease developed in four marmosets d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9fb8383057134655d5a92e1d0751337
https://doi.org/10.1093/infdis/132.5.582
https://doi.org/10.1093/infdis/132.5.582