Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alfred, Legasse"'
Autor:
Rebecca Broeckel, Julie M Fox, Nicole Haese, Craig N Kreklywich, Soila Sukulpovi-Petty, Alfred Legasse, Patricia P Smith, Michael Denton, Carsten Corvey, Shiv Krishnan, Lois M A Colgin, Rebecca M Ducore, Anne D Lewis, Michael K Axthelm, Marie Mandron, Pierre Cortez, Jonathan Rothblatt, Ercole Rao, Ingo Focken, Kara Carter, Gopal Sapparapau, James E Crowe, Michael S Diamond, Daniel N Streblow
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005637 (2017)
Chikungunya virus (CHIKV) is a mosquito-borne virus that causes a febrile syndrome in humans associated with acute and chronic debilitating joint and muscle pain. Currently no licensed vaccines or therapeutics are available to prevent or treat CHIKV
Externí odkaz:
https://doaj.org/article/5f7ecbe755064591abb3daf909919650
Autor:
Dina Alzhanova, Erika Hammarlund, Jason Reed, Erin Meermeier, Stephanie Rawlings, Caroline A Ray, David M Edwards, Ben Bimber, Alfred Legasse, Shannon Planer, Jerald Sprague, Michael K Axthelm, David J Pickup, David M Lewinsohn, Marielle C Gold, Scott W Wong, Jonah B Sacha, Mark K Slifka, Klaus Früh
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004123 (2014)
Infections with monkeypox, cowpox and weaponized variola virus remain a threat to the increasingly unvaccinated human population, but little is known about their mechanisms of virulence and immune evasion. We now demonstrate that B22 proteins, encode
Externí odkaz:
https://doaj.org/article/5f6338d6e0b9485384bf5d3133f00bd8
Autor:
Kristen Haberthur, Flora Engelmann, Byng Park, Alex Barron, Alfred Legasse, Jesse Dewane, Miranda Fischer, Amelia Kerns, Monica Brown, Ilhem Messaoudi
Publikováno v:
PLoS Pathogens, Vol 7, Iss 11, p e1002367 (2011)
Primary infection with varicella zoster virus (VZV) results in varicella (more commonly known as chickenpox) after which VZV establishes latency in sensory ganglia. VZV can reactivate to cause herpes zoster (shingles), a debilitating disease that aff
Externí odkaz:
https://doaj.org/article/19f6022c83e14d1991f0477e163b6533
Autor:
Anne M Wertheimer, Jennifer L Uhrlaub, Alec Hirsch, Guruprasad Medigeshi, Jerald Sprague, Alfred Legasse, Jennifer Wilk, Clayton A Wiley, Peter Didier, Robert B Tesh, Kristy O Murray, Michael K Axthelm, Scott W Wong, Janko Nikolich-Žugich
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15514 (2010)
BACKGROUND:Risk of encephalitis from West Nile virus (WNV) infection increases dramatically with age. Understanding the basis of this susceptibility requires development of suitable animal models. Here, we investigated the immune response to WNV in o
Externí odkaz:
https://doaj.org/article/89d397768c9b4975998f3eb8b82d6c4a
Autor:
Ilhem Messaoudi, Alexander Barron, Mary Wellish, Flora Engelmann, Alfred Legasse, Shannon Planer, Don Gilden, Janko Nikolich-Zugich, Ravi Mahalingam
Publikováno v:
PLoS Pathogens, Vol 5, Iss 11, p e1000657 (2009)
Simian varicella virus (SVV), the etiologic agent of naturally occurring varicella in primates, is genetically and antigenically closely related to human varicella zoster virus (VZV). Early attempts to develop a model of VZV pathogenesis and latency
Externí odkaz:
https://doaj.org/article/0a7a555f3a094d2ba632ff0f06902415
Autor:
Luka, Cicin-Sain, Susan, Smyk-Pearson, Sue, Smyk-Paerson, Noreen, Currier, Laura, Byrd, Caroline, Koudelka, Tammie, Robinson, Gwendolyn, Swarbrick, Shane, Tackitt, Alfred, Legasse, Miranda, Fischer, Dragana, Nikolich-Zugich, Byung, Park, Theodore, Hobbs, Cynthia J, Doane, Motomi, Mori, Michael K, Axthelm, Michael T, Axthelm, Deborah A, Lewinsohn, Janko, Nikolich-Zugich
Publikováno v:
The Journal of Immunology. 184:6739-6745
Aging is usually accompanied by diminished immune protection upon infection or vaccination. Although aging results in well-characterized changes in the T cell compartment of long-lived, outbred, and pathogen-exposed organisms, their relevance for pri
Autor:
Nicole Haese, Craig Kreklywich, Alfred Legasse, Mark Heise, Michael Axthelm, Ilhelm Messoudi, Daniel N Streblow
Publikováno v:
The Journal of Immunology. 196:80.7-80.7
Chikungunya virus (CHIKV) is a positive-sense RNA, arthropod-borne Alphavirus. In recent years the largest recorded outbreak of CHIKV occurred in the Islands of the Indian Ocean and India. CHIKV has continued to spread causing millions of cases acros